《中醫(yī)方劑大辭典》治療消渴病用藥經(jīng)驗(yàn)研究
[Abstract]:Objective to analyze the prescription of the treatment of thirst in the Dictionary of traditional Chinese Medicine (TCM prescription Dictionary), and to use the system software of "traditional Chinese Medicine inheritance and assist platform", combined with the knowledge of traditional Chinese medicine, to explore the characteristics of drugs used in the treatment of thirst, and to guide the clinical practice. Methods the prescription screening was carried out to obtain the prescription for the treatment of thirst, to standardize its prescription, to count the high frequency drugs for the treatment of thirst elimination by statistical analysis of frequency, and to sum up the properties of the high frequency drugs on the basis of this. Rules analysis and entropy clustering of complex systems are used to analyze the relationship between drugs and discover new prescriptions. The relationship between drugs and drugs can be clearly displayed through the network display function. Results (1) 514 prescriptions for the treatment of diabetes were obtained by screening. (2) the results of frequency analysis showed that the Chinese herbs with frequency above 20 were: Ophiopogon japonicus (179), trichosanthin (150), ginseng (147), Coptis chinensis (139). Poria cocos (119), grilled licorice (115), Zhimu (94), Radix Rehmanniae (88), Astragalus membranaceus (73), Schisandra chinensis (72), Glycyrrhiza (67), Pueraria (60), Gypsum (59), Radix Rehmanniae (56), Scutellaria baicalensis (55), alisma orientalis (54), Oyster (51), ground bone skin (41), cinnamon (40), Angelica sinensis (39), Cornus officinalis (35), black plum (33), chicken inner gold (32), Sophora flavescens (32), keel (29), cuttlebone (29), potato root (28), peony (28), Trichosanthes (27), Phellodendron (27), Cuscuta chinensis (27), lead (26), yam (26), Cistanche deserticola (25), mulberry skin (24), peony skin (23), Baizhu (23), ginger (23), Poria god (22), antler (22), Asparagus (22), cimicium (21), Xuanshen (21), Gardenia (20). 3 on the basis of statistical analysis of frequency, the high-frequency drugs were analyzed. The results showed that the main ingredients used were "sweet" and "bitter". It is mainly attributed to kidney (21), lung (20), spleen channel (20), stomach channel (18) and liver channel (16). The results showed that there were 112 drug combinations, and the main drug pairs appeared in the top 10 were: Ophiopogon japonicus, Trichosanthin (83); Ophiopogon japonicus, Ginseng (79), Rhizoma Coptidis (71), Rhizoma Coptidis (63), Ophiopogon japonicus, Poria cocos (59), Ginseng, Poria cocos (59), Fried Glycyrrhiza uralensis, Radix Ophiopogonis (55), Radix Glycyrrhizae, Ginseng (52), Ophiopogon japonicus, Zhimu (51); Trichosanthin and Ginseng (51) .5 evolved 40 core drug combinations based on complex system entropy clustering algorithm. 6 16 core combinations were obtained by using unsupervised entropy hierarchical clustering method. There are 8 new prescriptions for the treatment of diabetes. Conclusion the prescription of TCM prescription Dictionary is mainly based on tonifying deficiency and clearing heat, tonifying deficiency from many aspects of qi, blood, yin and yang, using ginseng, astragalus, etc., to replenish qi and lift the body, and make use of Rehmannia Rehmanniae, which is known as Radix Rehmanniae, and makes use of Radix Rehmanniae. Angelica such as blood tonifying blood nourishing yin, using wheat winter, asparagus and other Yin-tonifying drugs to nourish yin and nourish Jin, using antler deer, Cistanche deserticola and other Yang-tonifying medicine tonifying kidney tonifying essence; Pay attention to the organic combination of sexual taste and menstruation in the treatment of thirst, the use of warm drugs in the treatment of thirst, in order to "lead to fire to the original", "Yang seeking Yin" effect; The application of traditional Chinese medicine inheritance assistant system software to multi-level analysis of ancient prescription and testing prescription to explore the relationship between potential drugs provides a new way for the research of traditional Chinese medicine in the future.
【學(xué)位授予單位】:華北理工大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R255.4
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