【摘要】：冠心病是一種多因性、復雜性疾病,單靶點的治療雖能夠在一定程度上改善某些替代指標,如狹窄的解除、斑塊的穩(wěn)定及脂質(zhì)水平的降低等,但始終存在著指標改善與臨床缺血癥狀及終點心血管事件風險不同步的矛盾。究其原因,在于對疾病認識和治療觀的割裂現(xiàn)象,常常陷入"重結(jié)構(gòu),輕功能""重形病,輕神變"的誤區(qū),把冠心病看成簡單的"血管-血液"病變,而忽略了"血-脈""心-神""神-脈"間的復雜關系,故筆者擬從"血-脈-心-神"共病共調(diào)的整體觀認識來闡釋中醫(yī)藥治療冠心病可能起效的機制。
[Abstract]:Coronary heart disease (CHD) is a multifactorial and complex disease. Although single target therapy can improve some alternative indexes to a certain extent, such as the release of stenosis, the stability of plaque and the decrease of lipid level, and so on. However, there is always a contradiction between the improvement of indexes and the risk of clinical ischemic symptoms and end-point cardiovascular events. The reason lies in the splitting of the understanding and treatment of the disease, which often falls into the misconception of "heavy structure, light function", "serious form disease, light change of mind", and regards coronary heart disease as a simple "vascular-blood" lesion. While ignoring the complicated relationship between "blood-pulse", "heart-spirit" and "spirit-pulse", the author intends to explain the possible mechanism of Chinese medicine in treating coronary heart disease from the holistic view of "blood-pulse-heart-mind-spirit" co-ill consonant with "blood-pulse-heart-spirit".
【作者單位】： 天津中醫(yī)藥大學;天津中醫(yī)藥大學第一附屬醫(yī)院;
【基金】：國家自然科學基金資助項目(81473634)-從滋養(yǎng)血管成熟化探討四妙勇安湯穩(wěn)定動脈粥樣硬化斑塊的機制 國家中醫(yī)藥管理局項目(國醫(yī)大師阮士怡名醫(yī)傳承工作室)
【分類號】：R259
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本文編號：2438425