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大接經(jīng)針法與常規(guī)針刺治療肝氣郁結(jié)型輕中度抑郁癥的臨床療效比較研究

發(fā)布時(shí)間:2019-01-06 20:40
【摘要】:目的:比較運(yùn)用大接經(jīng)針法與常規(guī)針刺治療肝氣郁結(jié)型輕中度抑郁癥的臨床療效差異,由此驗(yàn)證大接經(jīng)針法治療肝氣郁結(jié)型輕中度抑郁癥的可行性及優(yōu)越性。方法:選取自2014年12月至2016年12月大連醫(yī)科大學(xué)附屬第二醫(yī)院針灸門診確診為肝氣郁結(jié)型輕中度抑郁癥患者共計(jì)72例,根據(jù)治療方法的不同,隨機(jī)分為常規(guī)針刺組(A)、電針組(B)、大接經(jīng)組(C)三組進(jìn)行治療,每組均為24例,其中常規(guī)針刺組(A)入組為24例,脫落1例,共計(jì)23例;電針組(B)入組為24例,脫落3例,共計(jì)21例;大接經(jīng)組(C)入組為24例,脫落2例,共計(jì)22例。常規(guī)針刺組取基本穴位:百會(huì)、印堂、四神聰、太陽、風(fēng)池、內(nèi)關(guān)、足三里、三陰交、陰陵泉、太沖,其中百會(huì)、四神聰、印堂、太陽以及風(fēng)池穴應(yīng)用平補(bǔ)平瀉手法,內(nèi)關(guān)、足三里、三陰交、陰陵泉以及太沖穴應(yīng)用迎隨補(bǔ)瀉手法;電針組則在常規(guī)針刺組取穴及補(bǔ)瀉方法的基礎(chǔ)上在百會(huì)、印堂穴連接電針;大接經(jīng)組取穴及補(bǔ)瀉方法同常規(guī)針刺組,起針后在十二經(jīng)井穴應(yīng)用大接經(jīng)針法,即按照少商到大敦的順序,依次點(diǎn)刺不留針,每日一次,兩側(cè)交替進(jìn)行。三組患者每日針刺一次,7次為一療程,連續(xù)治療6個(gè)療程。隨訪觀察三組患者治療前以及治療后抑郁量表(HAMD17項(xiàng)版本)評(píng)分、抑郁自評(píng)量表(SDS)評(píng)分、中醫(yī)證候量化表評(píng)分及三種量表評(píng)分的變化。所有患者均知情同意并且符合入組標(biāo)準(zhǔn),能夠耐受所有檢查以及針灸治療。將收集的患者數(shù)據(jù)建立數(shù)據(jù)庫,使用SPSS 22.0統(tǒng)計(jì)學(xué)軟件對(duì)數(shù)據(jù)分析。計(jì)數(shù)資料采用x2檢驗(yàn);計(jì)量資料均數(shù)用?X±S表示,三組間均數(shù)比較使用單因素方差分析,兩兩比較則使用獨(dú)立樣本t檢驗(yàn),組內(nèi)前后比較采用配對(duì)樣本t檢驗(yàn),均以P0.05認(rèn)為有統(tǒng)計(jì)學(xué)意義。結(jié)果:1.HAMD總分均值比較:(1)組內(nèi)比較:三組治療后HAMD總分均值均比治療前降低,C組(大接經(jīng)組)P0.01,有顯著性差異,A、B組P0.05,差異有統(tǒng)計(jì)學(xué)意義。(2)組間比較:A(常規(guī)針刺組)、B(電針組)比較P=0.618(P0.05),差異無統(tǒng)計(jì)學(xué)意義;A組(常規(guī)針刺組)、C組(大接經(jīng)組)P=0.005(P0.01),有顯著性差異;B組(電針組)、C組(大接經(jīng)組)P=0.02(P0.05),差異有統(tǒng)計(jì)學(xué)意義。2.SDS總分均值比較:(1)組內(nèi)比較:三組治療后SDS總分均值均較治療以前降低,A、B、C組P均小于0.05,差異有統(tǒng)計(jì)學(xué)意義。(2)組間比較:A(常規(guī)針刺組)、B(電針組)P=0.008(P0.01),有顯著性差異;A(常規(guī)針刺組)、C(大接經(jīng)組)P=0.001(P0.01),有顯著性差異;B組(電針組)、C組(大接經(jīng)組)P=0.306(P0.05),差異無統(tǒng)計(jì)學(xué)意義。3.中醫(yī)證候量化表總分比較:(1)組內(nèi)比較:三組治療后中醫(yī)證候量化表總分均值均較治療前降低,三組P均小于0.05,差異有統(tǒng)計(jì)學(xué)意義。(2)組間比較:A(常規(guī)針刺組)、B(電針組)P=0.029(P0.05),差異有統(tǒng)計(jì)學(xué)意義;A(常規(guī)針刺組)、C(大接經(jīng)組)P=0.001(P0.01),有顯著性差異;B組(電針組)、C組(大接經(jīng)組)P=0.046(P0.05),差異有統(tǒng)計(jì)學(xué)意義。4.總有效率比較:大接經(jīng)組總有效率是81.82%;電針組總有效率是71.43%;常規(guī)針刺組總有效率是65.22%,大接經(jīng)組總有效率高于電針組和常規(guī)針刺組,差異具有統(tǒng)計(jì)學(xué)意義。結(jié)論:1.大接經(jīng)結(jié)合常規(guī)針刺治療肝氣郁結(jié)型輕中度抑郁癥療效明顯優(yōu)于電針及常規(guī)針刺治療,顯著改善了患者心境低落、思維遲緩、睡眠障礙等癥狀。2.大接經(jīng)針法通過針刺井穴以激發(fā)經(jīng)氣的起始狀態(tài),調(diào)整全身經(jīng)絡(luò)的虛實(shí),調(diào)節(jié)機(jī)體陰陽平衡,從而達(dá)到疏肝解郁、醒腦開竅的作用,充分證明了大接經(jīng)針法在抑郁癥臨床治療中的作用。
[Abstract]:Objective: To compare the clinical curative effect of the traditional acupuncture on the treatment of mild and moderate depression of the liver-qi depression, and to verify the feasibility and the superiority of the large-joint needle method in the treatment of the mild-to-moderate depression of the liver-qi. Methods: A total of 72 patients with mild and moderate depression diagnosed by acupuncture and moxibustion in the second hospital from December 2014 to December 2016 were randomly divided into the conventional acupuncture group (A) and the electroacupuncture group (B) according to the different treatment methods. The group (C) was treated in three groups, each group was 24 cases, in which 24 cases were in the conventional acupuncture group (A), 1 case was dropped, 23 cases were dropped, 24 cases were dropped in the electroacupuncture group (B), 3 cases were dropped, 21 cases were in total, 24 cases of the large-joint group (C) and 2 in the fall-off group. A total of 22 cases were reported. The conventional acupuncture group takes the basic acupuncture points: hundreds of meetings, indents, four-god-cong, the sun, the wind pool, the inner-off, the foot-three, the three-yin, the yin-ling spring and the undershoot, wherein the hundreds, the four-god-cong, the print hall, the sun and the wind-pool point are applied with a flat-and-back-up method, an inner-off, a foot-three, a three-yin, The electroacupuncture group is connected with the electro-acupuncture at hundreds of times on the basis of the conventional acupuncture group and the method of tonifying and purging, and the acupuncture group is connected with the conventional acupuncture group through the group taking point and the reinforcing and discharging method, and the acupuncture point method is applied to the twelve through well holes after the needle is used as the needle, That is, according to the order of the young business to the big town, the needle is not left in sequence, once a day, and the two sides are alternately carried out. The three groups of patients were acupuncture once a day, 7 times a course of treatment, and 6 courses of treatment were treated continuously. All three groups were followed up for three groups: pre-treatment and post-treatment depression scale (HAMD17 version) score, depression self-rating scale (SDS) score, syndrome score of TCM syndrome, and change of three scales. All patients had informed consent and met the enrollment criteria to be able to withstand all examinations and acupuncture and moxibustion. The collected patient data was established in the database and the data was analyzed using the SPSS 10.0 statistical software. x2 test is used for counting data, and the number of measurement data is used? X-S indicated that the two comparisons used single-factor analysis of variance, the two comparisons used independent sample t-test, and the pre-and post-group comparisons were tested with the paired samples t, both of which were considered to be of statistical significance. Results: 1. The mean value of the total score of HAMD was as follows: (1) The mean value of the total score of HAMD after three groups of treatment was lower than that of the treatment before treatment. (2) Compared with group A (conventional acupuncture group) and B (electroacupuncture group), P = 0.618 (P0.05), the difference was not significant; group A (conventional acupuncture group), group C (large group) P = 0. 005 (P0.01), there was significant difference; group B (electroacupuncture group), group C (large group of group) P = 0.02 (P0.05), There was a significant difference in the mean value of SDS total score: (1) The mean value of SDS total score was lower in group A, B and C after three groups of treatment, and that of group A, B and C was less than 0.05, and the difference was significant. (2) In group A (conventional acupuncture group), group B (electroacupuncture group) P = 0. 008 (P0.01), there was a significant difference; in group A (conventional acupuncture group), C (large group of acupuncture group), P = 0.001 (P0.01), there was a significant difference; group B (electroacupuncture group), group C (large group by group) P = 0.306 (P0.05), and the difference was not statistically significant. The total score of the total score of the post-treatment of TCM syndrome in the three groups was lower than that of the pre-treatment group (P <0.05), and the difference was of statistical significance. (2) In group A (conventional acupuncture group), B (electroacupuncture group) P = 0.029 (P0.05), the difference was of statistical significance; group A (conventional acupuncture group), C (large group of acupuncture group) P = 0.001 (P0.01), there was significant difference; group B (electroacupuncture group), group C (large group of group) P = 0.046 (P0.05), the difference was statistically significant. The total effective rate of the electroacupuncture group was 81.82%, the total effective rate of the electroacupuncture group was 71.43%, the total effective rate of the conventional acupuncture group was 65. 22%, the total effective rate of the large-joint group was higher than that of the electroacupuncture group and the conventional acupuncture group, and the difference was of statistical significance. Conclusion: 1. the curative effect of the large-joint combined with the conventional acupuncture for treating the depressed mild-to-moderate depression of the liver-qi is obviously superior to that of the electro-acupuncture and the conventional acupuncture treatment, and the symptoms of depression of the mood of the patient, the delay of the thinking, the sleep disorder and the like are obviously improved. The large-joint needle method is used for stimulating the initial state of the gas through the acupuncture well hole, regulating the deficiency and the excess of the whole body and collaterals, regulating the balance of the yin and yang of the body, so as to achieve the effects of soothing the liver and resolving the depression, and restoring the brain and inducing resuscitation, and fully proves the effect of the large-joint acupuncture method in the clinical treatment of the depression.
【學(xué)位授予單位】:大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R246.6

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