【摘要】：目的:通過觀察柴平湯加減治療功能性消化不良餐后不適綜合征的臨床療效,探討柴平湯的作用機(jī)理,為臨床治療提供參考。方法:收集功能性消化不良餐后不適綜合征患者60例,隨機(jī)分為治療組和對(duì)照組,每組30例。兩組患者均要求調(diào)節(jié)情志,清淡易消化飲食,停用所有可能影響療效判定的藥物,記錄所有患者在用藥前后的癥狀積分。治療組予柴平湯加減治療,對(duì)照組予達(dá)利通顆粒治療,療程均為4周,治療結(jié)束后,比較兩組治療前后的癥狀積分及綜合療效。采用SPSS17.0統(tǒng)計(jì)軟件對(duì)所有數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。結(jié)果:1、治療組30例,痊愈8例,顯效11例,好轉(zhuǎn)9例,無效2例,總有效率93.3%;對(duì)照組30例,痊愈2例,顯效4例,好轉(zhuǎn)18例,無效6例,總有效率80.0%;提示治療組臨床綜合療效優(yōu)于對(duì)照組,總有效率優(yōu)于對(duì)照組(P0.01)。2、兩組患者的癥狀總積分、單癥積分,治療前后相比均有好轉(zhuǎn),治療后與治療前比較有差異(P0.05),其中在腹脹、早飽、噯氣、煩躁、精神疲憊、肢體疲乏、上腹痛、納食減少癥狀改善方面,治療組效果優(yōu)于對(duì)照組(P0.05)。在咽部梗阻感、上腹灼熱癥狀改善上,兩組結(jié)果無顯著差異(P0.05)。3、兩組患者在治療期間均未發(fā)生明顯的不良反應(yīng),其治療前后實(shí)驗(yàn)室檢查血、尿、便常規(guī)、肝功及腎功均未發(fā)現(xiàn)明顯異常。相關(guān)數(shù)據(jù)經(jīng)統(tǒng)計(jì)學(xué)分析,無統(tǒng)計(jì)學(xué)意義(P0.05),兩組藥物治療PDS,無毒副作用,安全可靠。結(jié)論:柴平湯加減治療功能性消化不良餐后不適綜合征療效顯著,其總有效率高于對(duì)照組,在改善患者腹脹、早飽、噯氣等癥狀及臨床綜合療效方面,優(yōu)于對(duì)照組,未發(fā)生明顯的不良反應(yīng)。
[Abstract]:Objective: to observe the clinical effect of Qaiping decoction on functional dyspepsia postprandial discomfort syndrome and to explore the mechanism of Qaiping decoction. Methods: 60 patients with functional dyspepsia were randomly divided into treatment group (n = 30) and control group (n = 30). The patients in both groups were required to adjust their emotions, to digest their diet easily, to stop all drugs that might affect the evaluation of curative effect, and to record the symptom scores of all patients before and after the treatment. The treatment group was treated with Qaiping decoction and the control group was treated with Dalitong granule for 4 weeks. After the treatment, the symptom score and the comprehensive curative effect of the two groups before and after treatment were compared. All the data were analyzed by SPSS17.0 software. Results: 1. In the treatment group, 30 cases were cured, 8 cases were cured, 11 cases were improved, 9 cases were improved, 2 cases were ineffective, the total effective rate was 93.3 cases, in the control group, 30 cases were cured, 2 cases were cured, 4 cases were markedly effective, 18 cases were improved, 6 cases were ineffective, the total effective rate was 80.0g. It is suggested that the clinical comprehensive curative effect of the treatment group is better than that of the control group, and the total effective rate is better than that of the control group (P0.01). After treatment compared with the treatment before the difference (P0.05), which in abdominal distension, early satiety, belching, irritability, mental fatigue, limb fatigue, upper abdominal pain, reducing symptoms of food intake improvement, the treatment group was better than the control group (P0.05). There was no significant difference between the two groups in the improvement of pharyngeal obstruction and the symptoms of upper abdominal burning (P0.05). 3. There was no significant adverse reaction between the two groups during the treatment, and the blood, urine, and routine tests were performed in the laboratory before and after treatment. No obvious abnormality was found in liver function and renal function. Related data were statistically analyzed, no statistical significance (P0.05), the two groups of drug treatment PDS, no side effects, safe and reliable. Conclusion: Qaiping decoction has a significant curative effect on functional dyspepsia postprandial discomfort syndrome, and its total effective rate is higher than that of control group. It is superior to the control group in improving abdominal distension, early satiety, belching and other symptoms and clinical comprehensive curative effect. There was no obvious adverse reaction.
【學(xué)位授予單位】：山西中醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 劉晶;李峰;唐旭東;馬捷;白世敬;劉艷陽;;功能性消化不良的中醫(yī)學(xué)機(jī)制研究探討[J];河北中醫(yī);2014年11期

2 劉佳;曾青山;;周福生辨治功能性消化不良舉隅[J];遼寧中醫(yī)雜志;2014年09期

3 戚建芬;;中西醫(yī)結(jié)合治療功能性消化不良療效觀察[J];山西中醫(yī);2014年08期

4 張殿華;;多種藥物聯(lián)合應(yīng)用治療功能性消化不良[J];中外醫(yī)療;2014年17期

5 曾靜;;辨證分型治療功能性消化不良52例臨床觀察[J];醫(yī)學(xué)理論與實(shí)踐;2014年11期

6 祁家和;孫建立;;多潘立酮配合小劑量奧美拉唑治療功能性消化不良的療效觀察[J];當(dāng)代醫(yī)學(xué);2014年13期

7 曹揚(yáng);梁志濤;張善舉;;張善舉教授治療功能性消化不良臨證經(jīng)驗(yàn)[J];中醫(yī)臨床研究;2014年02期

8 周方園;張照蘭;;張照蘭教授治療功能性消化不良經(jīng)驗(yàn)[J];中醫(yī)臨床研究;2013年24期

9 馮云萍;;柴平湯加減治療功能性消化不良臨床觀察[J];山西中醫(yī);2013年08期

10 仝甲釗;曲波;王蓓蓓;白梅;;功能性消化不良的發(fā)病機(jī)制[J];世界華人消化雜志;2013年09期

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