【摘要】：目的探究清營湯對感染乙肝病毒導(dǎo)致肝硬化的患者體內(nèi)血清生長激素及肝纖維化指標變化的影響。方法選擇2012年5月-2016年5月醫(yī)院治療的104例乙肝病毒感染后肝硬化患者為研究對象,按照隨機數(shù)表法將患者分為試驗組和對照組,每組52例,對照組患者進行注射異甘草酸鎂注射液等保肝治療,試驗組患者在對照組的基礎(chǔ)上給予患者清營湯治療,比較兩組患者治療前后的血清生長激素(GH)和纖維化指標:透明質(zhì)酸(HA)、層粘連蛋白(LN)、Ⅲ型前膠原(PC-Ⅲ)、Ⅳ型膠原(Ⅳ-C),比較兩組患者治療前后肝儲備功能ChildPugh評分。結(jié)果治療后對照組患者血清生長激素為(4.51±4.12)ug/L,透明質(zhì)酸為(141.5±24.7)ug/L,層粘連蛋白(173.6±24.8)ug/L,Ⅲ型前膠原為(119.2±15.4)ug/L,Ⅳ型膠原為(104.4±12.6)ug/L,試驗組患者血清生長激素為(2.98±3.28)ug/L,透明質(zhì)酸為(107.2±14.7)ug/L,層粘連蛋白(139.5±17.1)ug/L,Ⅲ型前膠原為(82.2±10.9)ug/L,Ⅳ型膠原為(67.3±9.1)ug/L,兩組比較差異有統(tǒng)計學意義(P0.05);治療后對照組患者肝臟儲備功能(Child-Pugh)評分為(6.8±1.1)分,試驗組為(5.9±0.8)分,兩組比較差異有統(tǒng)計學意義(P0.05)。結(jié)論清營湯能夠有效降低乙肝病毒感染導(dǎo)致的肝硬化患者體內(nèi)的血清生長激素和纖維化指標水平,有效治療肝硬化患者。
[Abstract]:Objective to investigate the effect of Qingying decoction on serum growth hormone and liver fibrosis index in patients with liver cirrhosis caused by hepatitis B virus. Methods 104 patients with hepatitis B virus posthepatitic cirrhosis treated in hospital from May 2012 to May 2016 were randomly divided into two groups: experimental group (n = 52) and control group (n = 52). The patients in the control group were treated with injection of magnesium isoglycyrrhizinate and other liver protection therapy, while the patients in the experimental group were treated with Qingying decoction on the basis of the control group. Serum growth hormone (GH) and fibrosis indexes before and after treatment were compared between the two groups: (HA), hyaluronic acid (HA), laminin (LN), type 鈪，

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