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通絡(luò)解語(yǔ)丸配合針刺治療中風(fēng)后假性球麻痹臨床觀察

發(fā)布時(shí)間:2018-09-17 18:53
【摘要】:目的:觀察通絡(luò)解語(yǔ)丸配合針刺治療中風(fēng)后假性球麻痹的臨床療效。方法:依據(jù)本案已選定的中、西醫(yī)診斷標(biāo)準(zhǔn)、病例納入標(biāo)準(zhǔn)和病例排除標(biāo)準(zhǔn),通過使用隨機(jī)數(shù)字表法,將入選的病例(共計(jì)64例),且辨證為痰瘀阻絡(luò)型假性球麻痹的患者,隨機(jī)分為兩組各32例(分為治療組和對(duì)照組)。在治療方面,對(duì)照組僅使用基礎(chǔ)治療,而治療組則在基礎(chǔ)治療的基礎(chǔ)上,加用通絡(luò)解語(yǔ)丸配合針刺治療。其中入選的64例患者,其入院時(shí)間即為入組第1天,總療程共計(jì)14天。于治療前后,觀察兩組患者在洼田飲水試驗(yàn)、假性球麻痹各項(xiàng)臨床表現(xiàn)和中醫(yī)證候積分以及改良日常生活能力評(píng)分之間的差異性,進(jìn)行相應(yīng)的臨床療效判定。本試驗(yàn)中得到的相關(guān)數(shù)據(jù)資料,采用科學(xué)的統(tǒng)計(jì)學(xué)分析方法,即spss21.0數(shù)據(jù)分析軟件處理。結(jié)果:1.入選的兩組患者,在一般資料(性別、年齡及病程)比較:采用統(tǒng)計(jì)學(xué)中X2檢驗(yàn)及t檢驗(yàn),比較結(jié)果顯示:兩組患者在性別、年齡及病程方面P0.05,表明無明顯差異,有統(tǒng)計(jì)學(xué)意義。2.治療后比較:經(jīng)治,治療組及對(duì)照組患者吞咽飲水功能障礙均得到不同程度的改善(P0.05),但治療組療效明顯優(yōu)于對(duì)照組(P0.05);經(jīng)治,治療組及對(duì)照組假性球麻痹的各項(xiàng)臨床表現(xiàn)均有不同程度的改善(P0.05),但治療組療效明顯優(yōu)于對(duì)照組(P0.05);治療后,兩組改良日常生活能力評(píng)分?jǐn)?shù)值,均可增加(P0.05),但治療組的效果明顯優(yōu)于對(duì)照組(P0.05);經(jīng)治療,治療組、對(duì)照組患者的中醫(yī)證候積分均可降低(P0.05),但治療組療效明顯優(yōu)于對(duì)照組(P0.05)。3.治療組在治療腦卒中后假性球麻痹痰瘀阻絡(luò)型的臨床總有效率達(dá)到83.87%,對(duì)照組為65.63%,經(jīng)卡方檢驗(yàn),P=0.015(P0.05),兩組治療效果具有顯著差異。4.在安全性方面,治療前及治療后常規(guī)檢查血、尿常規(guī),肝、腎功能,比對(duì)前后結(jié)果發(fā)現(xiàn):兩組患者在整個(gè)治療過程中未見明顯肝腎損害及其他不良反應(yīng)。在本試驗(yàn)實(shí)施過程中,治療組1例患者因不能耐受針刺而未能完成實(shí)驗(yàn),自動(dòng)脫出本試驗(yàn),余患者均按要求完成試驗(yàn)。結(jié)論:通絡(luò)解語(yǔ)丸配合針刺治療,可明顯改善中風(fēng)后假性球麻痹(痰瘀阻絡(luò)型)臨床癥狀:能夠安全有效的改善中風(fēng)后假性球麻痹的吞咽、構(gòu)音功能,改良日常生活能力及中醫(yī)癥候積分。中藥聯(lián)合針刺的綜合治療方法確有良效,值得借鑒、學(xué)習(xí)與推廣。
[Abstract]:Objective: to observe the clinical effect of Tongluojieyu pills combined with acupuncture on pseudobulbar paralysis after stroke. Methods: according to the diagnostic criteria of traditional Chinese and western medicine, the criteria of inclusion and exclusion of cases, the selected cases (64 cases in total) were selected according to the method of random digital table, and the syndrome differentiation was the pseudobulbar paralysis of phlegm and blood stasis type. They were randomly divided into two groups, 32 cases in each group (treatment group and control group). In terms of treatment, the control group was treated only with basic therapy, while the treatment group was treated with Tongluojieyu pill combined with acupuncture on the basis of basic treatment. The admission time of 64 patients was the first day and the total course of treatment was 14 days. Before and after treatment, the differences among the clinical manifestations of pseudobulbar paralysis, the score of TCM syndromes and the scores of improved daily living ability were observed in Wata drinking water test, and the corresponding clinical efficacy was evaluated. The relevant data obtained in this experiment are processed by scientific statistical analysis method, I. E. spss21.0 data analysis software. The result is 1: 1. The general data (sex, age and course of disease) were compared between the two groups. The results showed that there was no significant difference between the two groups in sex, age and course of disease (P0.05). There is statistical significance. Comparison after treatment: treatment group and control group patients with dysphagia were improved to varying degrees (P0.05), but the treatment group was significantly better than the control group (P0.05); The clinical manifestations of pseudobulbar paralysis in the treatment group and the control group were improved to varying degrees (P0.05), but the curative effect in the treatment group was significantly better than that in the control group (P0.05). Can increase (P0.05), but the effect of the treatment group is significantly better than the control group (P0.05); after treatment, the treatment group, the control group, the TCM syndrome score can be reduced (P0.05), but the treatment group is significantly better than the control group (P0.05). 3. The total effective rate of the treatment group was 83.87 in treating pseudobulbar paralysis with phlegm and stasis after stroke, while that in the control group was 65.63. The therapeutic effect was significantly different between the two groups by chi-square test (P0.05). In terms of safety, blood, urine, liver and kidney function were examined before and after treatment. The results showed that there were no obvious liver and kidney damage and other adverse reactions in the whole course of treatment between the two groups. During the course of this experiment, one patient in the treatment group was unable to complete the experiment because he could not tolerate acupuncture, and the rest of the patients completed the experiment according to the requirements. Conclusion: Tongluojieyu pills combined with acupuncture therapy can obviously improve the clinical symptoms of pseudobulbar paralysis (phlegm and blood stasis type) after stroke: it can improve the function of swallowing and articulation of pseudobulbar paralysis after stroke. Improve the ability of daily life and TCM symptom score. The comprehensive treatment of traditional Chinese medicine combined with acupuncture has good effect and is worth learning and popularizing.
【學(xué)位授予單位】:河南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類號(hào)】:R255.2

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