基于醫(yī)案數(shù)據(jù)分析的血管性癡呆中醫(yī)證治規(guī)律研究
發(fā)布時(shí)間：2018-09-14 19:44
【摘要】：目的:通過統(tǒng)計(jì)軟件對(duì)中醫(yī)治療血管性癡呆醫(yī)案的證候、治則、藥物進(jìn)行分析,從而探索血管性癡呆的中醫(yī)辨證論治規(guī)律,進(jìn)而更好的指導(dǎo)臨床應(yīng)用,并為進(jìn)一步研究提供參考。方法:1.進(jìn)入“百鏈”網(wǎng)站搜索頁(yè)面,以“血管性癡呆+案”作為檢索的詞組,檢索結(jié)果為611條,篩選符合條件的醫(yī)案78條;以“血管性癡呆+經(jīng)驗(yàn)”為檢索詞,檢索結(jié)果為1194條,篩選符合條件的醫(yī)案35條。以113條血管性癡呆的中醫(yī)醫(yī)案作為研究材料。2.將113條醫(yī)案里記載的中醫(yī)證型、治法、使用藥物逐一輸入中醫(yī)傳承輔助系統(tǒng)軟件,再次校驗(yàn)輸入信息的正確性,并保存?zhèn)溆谩?.運(yùn)用中醫(yī)傳承輔助系統(tǒng)軟件中的統(tǒng)計(jì)報(bào)表系統(tǒng)和數(shù)據(jù)分析系統(tǒng)進(jìn)行相關(guān)數(shù)據(jù)的統(tǒng)計(jì)分析,并將所得的證候、治則、藥物頻次,以及核心藥對(duì)、新處方數(shù)據(jù)導(dǎo)出保存。結(jié)果:1.血管性癡呆醫(yī)案中的主要中醫(yī)辨證類型為痰瘀阻竅證、瘀血阻絡(luò)證、痰濁阻竅證、腎精虧虛證、髓海不足證。2.血管性癡呆醫(yī)案中常用化痰開竅、活血化瘀、補(bǔ)腎益髓、醒腦開竅、益氣活血的治療原則。3.血管性癡呆醫(yī)案共使用中藥224味,其中使用頻率最高的中藥依次為石菖蒲、遠(yuǎn)志、川芎、茯苓、丹參,并確定了藥物的關(guān)聯(lián)規(guī)則及關(guān)聯(lián)程度。4.通過中醫(yī)傳承輔助系統(tǒng)軟件運(yùn)用聚類分析方法對(duì)113條血管性癡呆醫(yī)案挖掘出了12組核心藥對(duì),進(jìn)一步在核心藥對(duì)的基礎(chǔ)上演化出6個(gè)新處方。結(jié)論:1.血管性癡呆的中醫(yī)辨證多為“痰”、“瘀”、“虛”,治療原則、常用中藥與辨證相吻合。2.運(yùn)用數(shù)據(jù)挖據(jù)的方法,把個(gè)別中醫(yī)經(jīng)驗(yàn)與中醫(yī)傳承輔助系統(tǒng)平臺(tái)對(duì)醫(yī)案的集成研究結(jié)合起來,獲得了中醫(yī)治療血管性癡呆的辨證論治規(guī)律。3.通過中醫(yī)傳承輔助系統(tǒng)軟件對(duì)臨床治療經(jīng)驗(yàn)進(jìn)行分析的結(jié)果具有一定的科學(xué)性,對(duì)于指導(dǎo)臨床及基礎(chǔ)應(yīng)用研究具有重要作用。
[Abstract]:Objective: to analyze the syndromes, principles and drugs of traditional Chinese medicine (TCM) in the treatment of vascular dementia by statistical software, so as to explore the law of syndrome differentiation and treatment of vascular dementia, and to guide the clinical application better. It also provides reference for further study. Method 1: 1. Enter the search page of "hundred chain" website, take "vascular dementia case" as the search phrase, search result is 611, screen 78 qualified medical cases, take "vascular dementia experience" as key word, search result is 1194, 35 articles of qualified medical records were screened. 113 cases of vascular dementia were used as the research materials. 2. 2. 113 cases of TCM syndrome type, treatment methods, the use of drugs one by one into the Chinese medicine heritage assistance system software, again check the correctness of input information, and save spare .3. The statistical report system and data analysis system in the software of traditional Chinese medicine heritage assistant system are used to carry on the statistical analysis of relevant data, and the data of syndrome, treatment rule, drug frequency, core drug pair and new prescription are exported and preserved. The result is 1: 1. The main types of TCM syndrome differentiation in vascular dementia cases are phlegm stasis syndrome, blood stasis syndrome, phlegm stagnation syndrome, kidney essence deficiency syndrome, marrow sea deficiency syndrome. Vascular dementia commonly used in the medical records of phlegm resuscitation, blood circulation, tonifying kidney and marrow, waking up the brain and opening the orifices, invigorating qi and activating blood circulation treatment principle. 3. Vascular dementia cases used 224 Chinese medicine, in which the highest frequency of use of traditional Chinese medicine is Acorus calamus, Radix Polygala, Ligusticum chuanxiong, Poria cocos, Salvia miltiorrhiza, and determined the drug association rules and correlation degree. 4. Twelve groups of core drug pairs were excavated from 113 cases of vascular dementia by using the software of traditional Chinese Medicine inheritance Assistance system, and 6 new prescriptions were further developed on the basis of core drug pairs. Conclusion 1. The traditional Chinese medicine differentiation of vascular dementia is mostly "phlegm", "stasis", "deficiency", treatment principle. By using the method of data digging, combining the experience of individual TCM with the integrated research of medical records based on the platform of traditional Chinese Medicine (TCM) inheritance Assistant system, the law of syndrome differentiation and treatment of vascular dementia by TCM was obtained. It is scientific to analyze the clinical experience through the software of traditional Chinese Medicine (TCM) inheritance Assistant system, which is important for guiding clinical and basic application research.
【學(xué)位授予單位】：河北大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R277.7
[Abstract]:Objective: to analyze the syndromes, principles and drugs of traditional Chinese medicine (TCM) in the treatment of vascular dementia by statistical software, so as to explore the law of syndrome differentiation and treatment of vascular dementia, and to guide the clinical application better. It also provides reference for further study. Method 1: 1. Enter the search page of "hundred chain" website, take "vascular dementia case" as the search phrase, search result is 611, screen 78 qualified medical cases, take "vascular dementia experience" as key word, search result is 1194, 35 articles of qualified medical records were screened. 113 cases of vascular dementia were used as the research materials. 2. 2. 113 cases of TCM syndrome type, treatment methods, the use of drugs one by one into the Chinese medicine heritage assistance system software, again check the correctness of input information, and save spare .3. The statistical report system and data analysis system in the software of traditional Chinese medicine heritage assistant system are used to carry on the statistical analysis of relevant data, and the data of syndrome, treatment rule, drug frequency, core drug pair and new prescription are exported and preserved. The result is 1: 1. The main types of TCM syndrome differentiation in vascular dementia cases are phlegm stasis syndrome, blood stasis syndrome, phlegm stagnation syndrome, kidney essence deficiency syndrome, marrow sea deficiency syndrome. Vascular dementia commonly used in the medical records of phlegm resuscitation, blood circulation, tonifying kidney and marrow, waking up the brain and opening the orifices, invigorating qi and activating blood circulation treatment principle. 3. Vascular dementia cases used 224 Chinese medicine, in which the highest frequency of use of traditional Chinese medicine is Acorus calamus, Radix Polygala, Ligusticum chuanxiong, Poria cocos, Salvia miltiorrhiza, and determined the drug association rules and correlation degree. 4. Twelve groups of core drug pairs were excavated from 113 cases of vascular dementia by using the software of traditional Chinese Medicine inheritance Assistance system, and 6 new prescriptions were further developed on the basis of core drug pairs. Conclusion 1. The traditional Chinese medicine differentiation of vascular dementia is mostly "phlegm", "stasis", "deficiency", treatment principle. By using the method of data digging, combining the experience of individual TCM with the integrated research of medical records based on the platform of traditional Chinese Medicine (TCM) inheritance Assistant system, the law of syndrome differentiation and treatment of vascular dementia by TCM was obtained. It is scientific to analyze the clinical experience through the software of traditional Chinese Medicine (TCM) inheritance Assistant system, which is important for guiding clinical and basic application research.
【學(xué)位授予單位】：河北大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R277.7
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