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慢性便秘患者報(bào)告臨床結(jié)局(CC-PRO)評(píng)估量表在中醫(yī)治療中的應(yīng)用

發(fā)布時(shí)間:2018-09-09 08:47
【摘要】:目的:慢性便秘患者報(bào)告臨床結(jié)局(CC-PRO)量表,為南京市中醫(yī)院盆底中心自制量表。此研究通過(guò)在臨床中使用,評(píng)價(jià)CC-PRO量表和便秘患者生活質(zhì)量自評(píng)問(wèn)卷(PAC-QOL)的相關(guān)性,以及研究?jī)闪勘韺?duì)慢性便秘患者生活質(zhì)量的評(píng)價(jià)比較。通過(guò)兩量表進(jìn)行對(duì)比,對(duì)CC-PRO量表在中醫(yī)臨床中的作用進(jìn)行評(píng)價(jià)。方法:在盆底診療中心專(zhuān)病門(mén)診收集慢性便秘患者,共104例納入研究;颊咧委熐昂蠓謩e填寫(xiě)CC-PRO和PAC-QOL量表,并同時(shí)填寫(xiě)便秘嚴(yán)重度評(píng)分(CSS)量表做基線。治療根據(jù)患者的便秘分型及病情,由醫(yī)生選擇合適的治療方法,包括中藥、針灸、生物反饋治療。統(tǒng)計(jì)量表的結(jié)果,用SPSS軟件進(jìn)行數(shù)據(jù)分析。結(jié)果:①對(duì)不同分型的便秘患者,臨床上優(yōu)先選擇不同的治療方案,其中功能性排便障礙患者61例,占比59%。93%的功能性排便障礙患者行針灸配合生物反饋治療;慢傳輸型便秘患者25例,占比24%,88%的慢傳輸型便秘患者進(jìn)中藥治療;功能性排便障礙合并慢傳輸型便秘患者17例,占比16%,其中60%的行中藥配合針灸和生物反饋治療。②104例患者治療前的量表得分:CC-PRO治療前vs治療后:190.6±53.1vs131.4±79.3, P0.05; PAC-QOL治療前vs治療后:55.3±20.7vs55.3±20.7,P0.05; CSS治療前vs治療后:14.9±3.7vs9.0±4.7,P0.05;三個(gè)量表治療前后的得分均有統(tǒng)計(jì)學(xué)差異。③三個(gè)量表間均有相關(guān)性,CC-PRO量表和PAC-QOL量表的相關(guān)系數(shù)r=0.855; CC-PRO與CSS的相關(guān)系數(shù)r=0.629; PAC-QOL與CSS的相關(guān)系數(shù)r=0.520。CC-PRO量表的各維度(生理維度、心理維度、社會(huì)維度和滿意度)和PAC-QOL量表各維度(軀體不適、心理社會(huì)不適、擔(dān)憂、滿意度)間也具有相關(guān)性。④據(jù)治療方案的不同,將104名患者分為兩組:中藥組,包括主要采取中藥治療的患者,共42名。非中藥組,包括針灸和生物反饋治療的患者,共62名。兩組治療前基線均無(wú)統(tǒng)計(jì)學(xué)差異,治療后CSS量表和1PAC-QO L量表得分無(wú)統(tǒng)計(jì)學(xué)差異,CC-PRO量表的總分及CC-PRO的生理維度有統(tǒng)計(jì)學(xué)差異。結(jié)論:CC-PRO量表和PAC-QOL量表有較好相關(guān)性,在臨床中可以全面反映出患者的疾病嚴(yán)重程度和生活質(zhì)量狀況,在比較中醫(yī)藥治療方法的時(shí)候,CC-PRO可以反映出中醫(yī)藥治療對(duì)患者生理維度改善的優(yōu)勢(shì)。
[Abstract]:Objective: to report the clinical outcome (CC-PRO) of patients with chronic constipation. The purpose of this study was to evaluate the correlation between CC-PRO scale and self-rating quality of life (PAC-QOL) questionnaire for patients with constipation and to compare the two scales in evaluating the quality of life of patients with chronic constipation. Through the comparison of the two scales, the function of CC-PRO scale in TCM clinic was evaluated. Methods: 104 patients with chronic constipation were collected in pelvic floor clinic. CC-PRO and PAC-QOL were completed before and after treatment, and constipation severity score (CSS) was used as baseline. According to the patient's constipation type and condition, the treatment is selected by the doctor, including Chinese medicine, acupuncture, biofeedback therapy. The results of the statistical scale were analyzed by SPSS software. Results for the patients with different types of constipation, different treatment schemes were given priority clinically. Among them, 61 patients with functional defecation disorder (59.93%) were treated with acupuncture and biofeedback therapy. Twenty-five patients with slow transit constipation, accounting for 24% of the patients with slow transit constipation, were treated with traditional Chinese medicine, 17 patients with functional defecation with slow transit constipation, 17 patients with functional defecation and slow transit constipation, 60% of them received traditional Chinese medicine combined with acupuncture and biofeedback therapy. The scores of 20% of them before and after vs treatment were 190.6 鹵53.1vs131.4 鹵79.3, P0.05; before and after PAC-QOL, vs was 55.3 鹵20.7vs55.3 鹵20.7 P0.05; before and after vs treatment, vs was 0.14.9 鹵3.7vs9.0 鹵4.7P 0.05; There were significant differences in the scores of the three scales before and after treatment. 3 the correlation coefficients of CC-PRO scale and PAC-QOL scale was 0.855; the correlation coefficient between CC-PRO and CSS was 0.629; the correlation coefficient between PAC-QOL and CSS was every dimension of r=0.520.CC-PRO scale (physiological dimension, P < 0.05). There was also correlation between psychological dimension, social dimension and satisfaction degree and PAC-QOL scale dimension (somatic discomfort, psychosocial discomfort, worry, satisfaction degree). According to the difference of treatment plan, 104 patients were divided into two groups: traditional Chinese medicine group. Including the main treatment of traditional Chinese medicine patients, a total of 42. There were 62 patients in non-TCM group, including acupuncture and biofeedback therapy. There was no statistical difference in baseline before treatment between the two groups, but there was no statistical difference in the scores of CSS scale and 1PAC-QO L scale after treatment. The total score of CC-PRO scale and the physiological dimension of CC-PRO were statistically different. Conclusion the ratio of CC-PRO scale to PAC-QOL scale has a good correlation, and it can reflect the severity of disease and quality of life of patients in clinic. CC-PRO can reflect the advantages of traditional Chinese medicine in improving the physiological dimension of patients.
【學(xué)位授予單位】:南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類(lèi)號(hào)】:R256.35

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