基于文獻(xiàn)分析的中藥治療內(nèi)痔用藥規(guī)律及相關(guān)對比研究
發(fā)布時間：2018-09-04 20:22
【摘要】：目的:通過檢索古代醫(yī)籍文獻(xiàn)中以中藥內(nèi)治法、熏洗法、外用藥物治療法來治療內(nèi)痔的相關(guān)文獻(xiàn),探討非手術(shù)療法治療內(nèi)痔的用藥規(guī)律,為臨床治療本病提供理論依據(jù),為治愈或治療本病、減輕患者病痛,獻(xiàn)上新的思路。材料與方法:以《中華醫(yī)典》為研究的主體資料,以“痔”為關(guān)鍵詞進(jìn)行目錄搜索,依照選擇方藥的標(biāo)準(zhǔn)進(jìn)行篩選,對符合標(biāo)準(zhǔn)的用藥進(jìn)行相關(guān)統(tǒng)計研究。結(jié)果:1.古代內(nèi)治方藥中符合錄入標(biāo)準(zhǔn)的方劑316首,其中最大方劑用藥23味,最小方劑用藥僅1味,共涉及用藥392味,符合計入頻次統(tǒng)計的藥物206味,其他藥物187味,藥物出現(xiàn)總頻次1653次。2.古代內(nèi)治藥物中使用頻次位于前三位的藥物依次為:槐花、枳殼、當(dāng)歸;槐花用藥96頻次,相對頻次5.8%;枳殼與當(dāng)歸二者用藥均為86頻次,相對頻次5.2%。3.古代內(nèi)治藥物中使用頻次居前三位的藥物功效依次為:補(bǔ)虛藥、清熱藥及止血藥。補(bǔ)虛藥用藥總頻次317次,占用藥總頻數(shù)的19.2%,其中,補(bǔ)氣藥與補(bǔ)血藥的應(yīng)用共占補(bǔ)虛藥的85.5%,補(bǔ)氣藥以148味次居補(bǔ)虛藥首位;清熱藥以總191味次居補(bǔ)虛藥之后,占用藥總頻數(shù)的11.6%,其中,清熱燥濕藥、清熱解毒藥、清熱涼血藥三種類型以總頻次178味次占清熱藥用藥總頻數(shù)的93.2%;止血藥以總154味次居第三位,占用藥總頻次的9.3%,其中,涼血止血藥以總頻次124味次占止血藥用藥總頻數(shù)的80.5%。4.古代外用熏洗藥中符合錄入標(biāo)準(zhǔn)的方劑92首,其中最大方劑用藥17味,最小方劑用藥僅1味,共涉及用藥196味,符合計入頻次統(tǒng)計的藥物78味,其他藥物118味,藥物出現(xiàn)總頻次263次。5.古代熏洗藥物中使用頻次位于前三位的藥物依次為:荊芥、芒硝、白礬;其中,荊芥用藥25頻次,相對頻次9.5%;芒硝用藥23頻次,相對頻次8.7%;白礬用藥17頻次,相對頻次6.5%,二者分居二、三位。6.古代熏洗藥物中使用頻次位居前三位的藥物功效依次為:解表藥、清熱藥、以及同居第三位的瀉下藥與攻毒殺蟲止癢藥;現(xiàn)代熏洗藥中使用頻次位居前三位的藥物功效依次為:清熱藥、瀉下藥、攻毒殺蟲止癢藥。7.古代外用符合標(biāo)準(zhǔn)的方劑182首,其中最大方劑用藥10味,最小方劑用藥僅1味,共涉及用藥272味,符合計入頻次統(tǒng)計的藥物100味,其他藥物172味,藥物出現(xiàn)總頻次435次。8.古代外用藥物中使用頻次位于前三位的藥物依次為:白礬、冰片、麝香;白礬用藥44頻次,相對頻次10.1%;冰片用藥31頻次,相對頻次7.1%;麝香用藥22頻次,相對頻次5.1%。9.古代外用藥物中使用頻次位居前三位的藥物功效依次為:攻毒殺蟲止癢藥、清熱藥及開竅藥。結(jié)論:1.古代醫(yī)家治療內(nèi)痔,以口服用藥治療為主。2.古代醫(yī)家以內(nèi)治法治療內(nèi)痔重在以清熱涼血、止血、氣血同補(bǔ)為主要的治療方法。3.古代醫(yī)家以熏洗法治療內(nèi)痔時注重以祛風(fēng)解表、清熱軟堅、燥濕殺蟲止癢為主要的治療方法;現(xiàn)代醫(yī)家對內(nèi)痔的治療思想同古代醫(yī)家基本一致,而古代更注重解表,現(xiàn)代更注重燥濕。4.古代醫(yī)家以外用藥物治療內(nèi)痔時注重以殺蟲止癢、清熱、消腫生肌為主要的治療方法。5.古代內(nèi)治、熏洗、外用三類藥物中排名前三位的藥物各有異同,三者均包括清熱藥,治療時取清熱之意;內(nèi)治藥中同時注重補(bǔ)虛藥與止血藥的使用,意在清熱止血與調(diào)補(bǔ)氣血并行;熏洗藥與外用藥物二者均含有攻毒殺蟲止癢藥,意在殺蟲解毒、燥濕止癢;其中熏洗藥中除清熱外,還注重解表藥與瀉下藥的應(yīng)用,意在解表、軟堅;而外用藥物治療同時注重生肌、消腫、止痛療法。
[Abstract]:OBJECTIVE: To explore the medication regularity of non-operative therapy for internal hemorrhoids by searching the ancient medical literature on internal treatment of traditional Chinese medicine, fumigation and washing, and external drug therapy, so as to provide theoretical basis for clinical treatment of internal hemorrhoids, and provide new ideas for curing or treating the disease and alleviating the pain of patients. Results: 1. There were 316 prescriptions in ancient internal medicine prescriptions which met the entry criteria, of which 23 were the largest prescriptions and only 1 was the smallest prescription. 392 kinds of medicines accorded with the statistics of frequency, 206 kinds of medicines accorded with the statistics, 187 kinds of other medicines, the total frequency of drug occurrence was 1653.2. The first three medicines used in ancient internal medicine were: Sophora japonica, Fructus aurantii, Angelica sinensis; Sophora japonica 96 times, the relative frequency was 5.8%; Fructus aurantii and Angelica sinensis were 86 times, the relative frequency was 5.2%. Among them, 85.5% of the drugs were used for invigorating qi, 148 for invigorating qi, 191 for clearing away heat and 19.2% for invigorating qi, and 148 for invigorating qi. The total frequency was 11.6%. Among them, 178 times of the total frequency of the three types of antipyretic drugs accounted for 93.2% of the total frequency of antipyretic drugs; 154 times of the total number of hemostatic drugs accounted for the third place, accounting for 9.3% of the total frequency of drugs, of which, 124 times of the total frequency of cold blood hemostatic drugs accounted for 80.5% of the total frequency of hemostatic drugs in ancient times. Among the 92 prescriptions that met the entry criteria, 17 were the largest prescriptions and only 1 was the smallest prescription. There were 196 prescriptions involved, 78 were the medicines that accorded with the frequency statistics, and 118 were the other medicines. The total frequency of occurrence of the medicines was 263. Among them, there were 25 times, 9.5% relative frequency, 23 times, 8.7% relative frequency of mirabilite, 17 times, 6.5% relative frequency of alum, which were in the second and third place respectively. Among the 182 prescriptions used for external use in ancient times, 10 prescriptions were the largest and only 1 prescription was the smallest, involving 272 medicines, 100 medicines accorded with the statistics of frequency, 172 other medicines, and drugs. The frequencies of the first three drugs used in ancient external medicines were alum, borneol and musk, 44 times used in alum, 10.1% in relative frequencies, 31 times used in borneol, 7.1% in relative frequencies, 22 times used in musk, 5.1% in relative frequencies. Conclusion: 1. Ancient physicians treated internal hemorrhoids mainly by oral medication. 2. Ancient physicians treated internal hemorrhoids mainly by internal treatment with the methods of clearing away heat and cooling blood, stopping bleeding, reinforcing qi and blood. 3. Ancient physicians treated internal hemorrhoids by fumigation and washing, focusing on dispelling wind and relieving superficial symptoms, clearing away heat, softening firmness, drying dampness and killing. Ancient physicians pay more attention to relieving itching, clearing away heat, detumescence and muscle growth. 5. Ancient internal treatment, fumigation and washing, external use of three drugs in the treatment of internal hemorrhoids. The top three drugs have their own similarities and differences, all of them include antipyretic drugs, take the meaning of clearing away heat while treating; internal medicine at the same time pay attention to the use of tonifying deficiency drugs and hemostatic drugs, intended to clear away heat and hemostasis and regulating qi and blood at the same time; fumigation and lotion drugs and external medicine both contain poisonous insecticidal and itching drugs, intended to insecticidal detoxification, dryness and dampness; fumigation and washing drugs in which the elimination of Qingqing. In addition to heat, it also pays attention to the application of antiphlogistic and diarrheal drugs, intended to relieve the surface, soft and firm; while external medicine treatment at the same time pay attention to muscle, swelling, analgesic therapy.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R266
本文編號：2223229
[Abstract]:OBJECTIVE: To explore the medication regularity of non-operative therapy for internal hemorrhoids by searching the ancient medical literature on internal treatment of traditional Chinese medicine, fumigation and washing, and external drug therapy, so as to provide theoretical basis for clinical treatment of internal hemorrhoids, and provide new ideas for curing or treating the disease and alleviating the pain of patients. Results: 1. There were 316 prescriptions in ancient internal medicine prescriptions which met the entry criteria, of which 23 were the largest prescriptions and only 1 was the smallest prescription. 392 kinds of medicines accorded with the statistics of frequency, 206 kinds of medicines accorded with the statistics, 187 kinds of other medicines, the total frequency of drug occurrence was 1653.2. The first three medicines used in ancient internal medicine were: Sophora japonica, Fructus aurantii, Angelica sinensis; Sophora japonica 96 times, the relative frequency was 5.8%; Fructus aurantii and Angelica sinensis were 86 times, the relative frequency was 5.2%. Among them, 85.5% of the drugs were used for invigorating qi, 148 for invigorating qi, 191 for clearing away heat and 19.2% for invigorating qi, and 148 for invigorating qi. The total frequency was 11.6%. Among them, 178 times of the total frequency of the three types of antipyretic drugs accounted for 93.2% of the total frequency of antipyretic drugs; 154 times of the total number of hemostatic drugs accounted for the third place, accounting for 9.3% of the total frequency of drugs, of which, 124 times of the total frequency of cold blood hemostatic drugs accounted for 80.5% of the total frequency of hemostatic drugs in ancient times. Among the 92 prescriptions that met the entry criteria, 17 were the largest prescriptions and only 1 was the smallest prescription. There were 196 prescriptions involved, 78 were the medicines that accorded with the frequency statistics, and 118 were the other medicines. The total frequency of occurrence of the medicines was 263. Among them, there were 25 times, 9.5% relative frequency, 23 times, 8.7% relative frequency of mirabilite, 17 times, 6.5% relative frequency of alum, which were in the second and third place respectively. Among the 182 prescriptions used for external use in ancient times, 10 prescriptions were the largest and only 1 prescription was the smallest, involving 272 medicines, 100 medicines accorded with the statistics of frequency, 172 other medicines, and drugs. The frequencies of the first three drugs used in ancient external medicines were alum, borneol and musk, 44 times used in alum, 10.1% in relative frequencies, 31 times used in borneol, 7.1% in relative frequencies, 22 times used in musk, 5.1% in relative frequencies. Conclusion: 1. Ancient physicians treated internal hemorrhoids mainly by oral medication. 2. Ancient physicians treated internal hemorrhoids mainly by internal treatment with the methods of clearing away heat and cooling blood, stopping bleeding, reinforcing qi and blood. 3. Ancient physicians treated internal hemorrhoids by fumigation and washing, focusing on dispelling wind and relieving superficial symptoms, clearing away heat, softening firmness, drying dampness and killing. Ancient physicians pay more attention to relieving itching, clearing away heat, detumescence and muscle growth. 5. Ancient internal treatment, fumigation and washing, external use of three drugs in the treatment of internal hemorrhoids. The top three drugs have their own similarities and differences, all of them include antipyretic drugs, take the meaning of clearing away heat while treating; internal medicine at the same time pay attention to the use of tonifying deficiency drugs and hemostatic drugs, intended to clear away heat and hemostasis and regulating qi and blood at the same time; fumigation and lotion drugs and external medicine both contain poisonous insecticidal and itching drugs, intended to insecticidal detoxification, dryness and dampness; fumigation and washing drugs in which the elimination of Qingqing. In addition to heat, it also pays attention to the application of antiphlogistic and diarrheal drugs, intended to relieve the surface, soft and firm; while external medicine treatment at the same time pay attention to muscle, swelling, analgesic therapy.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R266
【參考文獻(xiàn)】
相關(guān)會議論文 前3條
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2 吳莉娟;賀平;;痔手術(shù)治療研究進(jìn)展[A];第十五屆中國中西醫(yī)結(jié)合大腸肛門病學(xué)術(shù)交流會議論文集萃[C];2012年
3 劉訪;王福磊;曹波;;痔的認(rèn)識及治療進(jìn)展[A];貴州省中西醫(yī)結(jié)合學(xué)會肛腸學(xué)會第五屆學(xué)術(shù)交流會暨新技術(shù)新進(jìn)展學(xué)習(xí)班論文匯編[C];2012年
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