陳秋教授自擬代綜方聯(lián)合穴位埋線治療脾虛濕阻型肥胖癥的臨床療效研究
發(fā)布時間：2018-08-28 07:14
【摘要】：目的探討陳秋教授自擬代綜方聯(lián)合穴位埋線治療脾虛濕阻型肥胖癥的臨床療效。方法選取2014年11月—2015年11月在成都中醫(yī)藥大學(xué)附屬醫(yī)院內(nèi)分泌科門診和肥胖門診就診的脾虛濕阻型肥胖癥患者74例,采用隨機(jī)數(shù)字表法分為對照組(n=38)和觀察組(n=36)。在接受基礎(chǔ)治療的同時,對照組患者采用代綜方+二甲雙胍治療,觀察組患者采用代綜方+穴位埋線治療,藥物治療周期均為12周。比較兩組患者治療前后的體格檢查指標(biāo)、相關(guān)實(shí)驗(yàn)室檢測指標(biāo)、中醫(yī)證候積分及臨床療效。結(jié)果治療前兩組患者身高、體質(zhì)量、腰圍、臀圍、大腿圍、BMI、腰高比比較,差異無統(tǒng)計學(xué)意義(P0.05)。治療后觀察組患者體質(zhì)量、腰圍、BMI、腰高比低于對照組,差異有統(tǒng)計學(xué)意義(P0.05);而兩組患者臀圍、大腿圍比較,差異無統(tǒng)計學(xué)意義(P0.05)。治療前兩組患者總膽固醇(TC)、三酰甘油(TG)、低密度脂蛋白膽固醇(LDL-C)、高密度脂蛋白膽固醇(HDL-C)比較,差異無統(tǒng)計學(xué)意義(P0.05)。治療后觀察組患者TG低于對照組,LDL-C高于對照組,差異有統(tǒng)計學(xué)意義(P0.05);而兩組患者TC、HDL-C比較,差異無統(tǒng)計學(xué)意義(P0.05)。治療前和治療后,兩組患者胰島素(Ins)比較,差異均無統(tǒng)計學(xué)意義(P0.05);不同時間點(diǎn)比較,差異有統(tǒng)計學(xué)意義(P0.05);治療方法與時間在Ins上不存在交互作用(P0.05)。治療后兩組患者Ins與治療前比較,差異均有統(tǒng)計學(xué)意義(P0.05);不同時間點(diǎn)比較,差異有統(tǒng)計學(xué)意義(P0.05);治療方法與時間在Ins上存在交互作用(P0.05)。治療前兩組患者胰島素抵抗指數(shù)(HOMA-IR)、胰島素敏感指數(shù)(ISI)、胰島β細(xì)胞功能(HOMA-β)比較,差異無統(tǒng)計學(xué)意義(P0.05)。治療后兩組患者HOMA-IR、ISI比較,差異無統(tǒng)計學(xué)意義(P0.05);觀察組患者HOMA-β低于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。治療前兩組患者中醫(yī)證候積分比較,差異無統(tǒng)計學(xué)意義(P0.05);治療后觀察組患者中醫(yī)證候積分低于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。觀察組患者西醫(yī)臨床療效、中醫(yī)證候療效均優(yōu)于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。治療前和治療后,兩組患者紅細(xì)胞計數(shù)(RBC)、白細(xì)胞計數(shù)(WBC)、血紅蛋白(Hb)、血小板計數(shù)(PLT)、ALT、AST、血肌酐(SCr)、血尿素氮(BUN)、尿酸(UA)比較,差異均無統(tǒng)計學(xué)意義(P0.05)。結(jié)論代綜方聯(lián)合穴位埋線治療可明顯改善脾虛濕阻型肥胖癥患者的臨床癥狀,減輕體質(zhì)量,增加胰島素敏感性,改善胰島素抵抗,療效顯著。
[Abstract]:Objective to investigate the clinical effect of Professor Chen Qiu's self-made comprehensive prescription combined with acupoint embedding on spleen deficiency dampness obstruction obesity. Methods from November 2014 to November 2015, 74 obese patients with spleen deficiency and dampness obstruction were selected from the Endocrinology Department and Obesity outpatient Clinic of affiliated Hospital of Chengdu University of traditional Chinese Medicine. They were randomly divided into control group (n = 38) and observation group (n = 36). At the same time, the patients in the control group were treated with metformin, while the patients in the observation group were treated with catgut embedding at the acupoint of the treatment group. The treatment period was 12 weeks. The physical examination indexes, laboratory indexes, TCM syndromes score and clinical efficacy were compared between the two groups before and after treatment. Results there was no significant difference in height, body mass, waist circumference, hip circumference, thigh circumference and waist height ratio between the two groups before treatment (P0.05). After treatment, the observation group patients' body weight, waist circumference, waist height ratio was lower than the control group, the difference was statistically significant (P0.05), while the two groups of patients hip circumference, thigh circumference, the difference was not statistically significant (P0.05). There was no significant difference in total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) between the two groups before treatment (P0.05). After treatment, the TG of the observation group was lower than that of the control group, and the difference was statistically significant (P0.05), while the TC,HDL-C of the two groups had no statistical significance (P0.05). Before and after treatment, there was no significant difference in insulin (Ins) between the two groups (P0.05); at different time points, the difference was statistically significant (P0.05); there was no interaction between treatment methods and time on Ins (P0.05). After treatment, the difference of Ins between the two groups was statistically significant (P0.05); at different time points, the difference was statistically significant (P0.05); the treatment method and time had interaction on Ins (P0.05). There was no significant difference in insulin resistance index (HOMA-IR), insulin sensitivity index (ISI),) 尾 cell function (HOMA- 尾) between the two groups before treatment (P0.05). There was no significant difference in HOMA-IR,ISI between the two groups after treatment (P0.05), while the HOMA- 尾 in the observation group was lower than that in the control group (P0.05). Before treatment, there was no significant difference in TCM syndrome score between the two groups (P0.05); after treatment, the TCM syndrome score of the observation group was lower than that of the control group, and the difference was statistically significant (P0.05). The clinical curative effect of western medicine and syndromes of TCM in the observation group were better than those in the control group, the difference was statistically significant (P0.05). Before and after treatment, there was no significant difference in erythrocyte count, (RBC), leukocyte count, (WBC), hemoglobin, (Hb), platelet count, (PLT) alt AST, serum creatinine, (SCr), urea nitrogen, (BUN), uric acid (UA) between the two groups (P0.05). Conclusion the clinical symptoms, body weight, insulin sensitivity and insulin resistance of obesity patients with spleen deficiency and dampness obstruction can be obviously improved by the combination of Daizhuangfang and acupoint embedding therapy.
【作者單位】： 成都中醫(yī)藥大學(xué)臨床醫(yī)學(xué)院;成都中醫(yī)藥大學(xué)附屬醫(yī)院內(nèi)分泌科;
【基金】：國家中醫(yī)藥管理局中醫(yī)藥標(biāo)準(zhǔn)化項(xiàng)目(SATCM-2015-BZ[204])——代謝綜合征中醫(yī)臨床診療指南的修訂
【分類號】：R249;R259
[Abstract]:Objective to investigate the clinical effect of Professor Chen Qiu's self-made comprehensive prescription combined with acupoint embedding on spleen deficiency dampness obstruction obesity. Methods from November 2014 to November 2015, 74 obese patients with spleen deficiency and dampness obstruction were selected from the Endocrinology Department and Obesity outpatient Clinic of affiliated Hospital of Chengdu University of traditional Chinese Medicine. They were randomly divided into control group (n = 38) and observation group (n = 36). At the same time, the patients in the control group were treated with metformin, while the patients in the observation group were treated with catgut embedding at the acupoint of the treatment group. The treatment period was 12 weeks. The physical examination indexes, laboratory indexes, TCM syndromes score and clinical efficacy were compared between the two groups before and after treatment. Results there was no significant difference in height, body mass, waist circumference, hip circumference, thigh circumference and waist height ratio between the two groups before treatment (P0.05). After treatment, the observation group patients' body weight, waist circumference, waist height ratio was lower than the control group, the difference was statistically significant (P0.05), while the two groups of patients hip circumference, thigh circumference, the difference was not statistically significant (P0.05). There was no significant difference in total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) between the two groups before treatment (P0.05). After treatment, the TG of the observation group was lower than that of the control group, and the difference was statistically significant (P0.05), while the TC,HDL-C of the two groups had no statistical significance (P0.05). Before and after treatment, there was no significant difference in insulin (Ins) between the two groups (P0.05); at different time points, the difference was statistically significant (P0.05); there was no interaction between treatment methods and time on Ins (P0.05). After treatment, the difference of Ins between the two groups was statistically significant (P0.05); at different time points, the difference was statistically significant (P0.05); the treatment method and time had interaction on Ins (P0.05). There was no significant difference in insulin resistance index (HOMA-IR), insulin sensitivity index (ISI),) 尾 cell function (HOMA- 尾) between the two groups before treatment (P0.05). There was no significant difference in HOMA-IR,ISI between the two groups after treatment (P0.05), while the HOMA- 尾 in the observation group was lower than that in the control group (P0.05). Before treatment, there was no significant difference in TCM syndrome score between the two groups (P0.05); after treatment, the TCM syndrome score of the observation group was lower than that of the control group, and the difference was statistically significant (P0.05). The clinical curative effect of western medicine and syndromes of TCM in the observation group were better than those in the control group, the difference was statistically significant (P0.05). Before and after treatment, there was no significant difference in erythrocyte count, (RBC), leukocyte count, (WBC), hemoglobin, (Hb), platelet count, (PLT) alt AST, serum creatinine, (SCr), urea nitrogen, (BUN), uric acid (UA) between the two groups (P0.05). Conclusion the clinical symptoms, body weight, insulin sensitivity and insulin resistance of obesity patients with spleen deficiency and dampness obstruction can be obviously improved by the combination of Daizhuangfang and acupoint embedding therapy.
【作者單位】： 成都中醫(yī)藥大學(xué)臨床醫(yī)學(xué)院;成都中醫(yī)藥大學(xué)附屬醫(yī)院內(nèi)分泌科;
【基金】：國家中醫(yī)藥管理局中醫(yī)藥標(biāo)準(zhǔn)化項(xiàng)目(SATCM-2015-BZ[204])——代謝綜合征中醫(yī)臨床診療指南的修訂
【分類號】：R249;R259
【相似文獻(xiàn)】
相關(guān)期刊論文 前10條
1 鄒本桂;穴位埋線治療痤瘡86例[J];中國鄉(xiāng)村醫(yī)生;2000年12期
2 馬向明;穴位埋線治療遺精36例[J];針灸臨床雜志;2000年06期
3 吳緒平,張道敬;穴位埋線治療癲癇54例[J];中國民間療法;2000年04期
4 王增;穴位埋線治療便秘[J];中國針灸;2002年08期
5 肖波;穴位埋線治療胃及十二指腸潰瘍218例[J];上海針灸雜志;2002年02期
6 龍煌;穴位埋線治療癲癇1例[J];上海針灸雜志;2003年04期
7 孟軍紅;穴位埋線治療矮身材98例[J];中國中醫(yī)藥科技;2003年05期
8 王素玲;;穴位埋線治療肥胖100例觀察[J];實(shí)用中醫(yī)內(nèi)科雜志;2006年01期
9 宋永紅;;穴位埋線治療癲癇2例[J];上海針灸雜志;2006年02期
10 張靜;莊禮興;;穴位埋線治療癲癇[J];針灸臨床雜志;2006年02期
相關(guān)會議論文 前10條
1 王光安;;推拿結(jié)合穴位埋線治療2型糖尿病28例[A];2011中國針灸學(xué)會年會論文集（摘要）[C];2011年
2 朱在卿;;穴位埋線治療偏頭痛療效觀察[A];山東省2013年神經(jīng)內(nèi)科學(xué)學(xué)術(shù)會議暨中國神經(jīng)免疫大會2013論文匯編[C];2013年
3 楊佩蘭;湯杰;沈毅韻;李t，
本文編號：2208674
本文鏈接：http://sikaile.net/zhongyixuelunwen/2208674.html
最近更新
教材專著
