【摘要】：目的：探究老年人低密度脂蛋白基線水平并做中醫(yī)證候分析,了解老年人低密度脂蛋白基線水平以及中醫(yī)證型分布情況,為優(yōu)化中國老年人降脂方案提供一定的依據(jù)。方法：隨機收集562例住院的老年患者,以望、聞、問、切為原則,通過刻下癥及其舌脈,并參考《中藥新藥臨床研究指導原則(試行)》(2002年)進行中醫(yī)辨證分型,記錄其入院LDL檢查結果。所有數(shù)據(jù)采用SPSS20.0統(tǒng)計軟件進行統(tǒng)計,采用的方法有卡方檢驗、單因素方差分析、相關性分析等。結果：562例老年患者中最小60歲,最大94歲,平均年齡72.61±9.462歲,年齡分組60～69歲,70～79歲,≥80歲。LDL平均值為2.9076±0.74492 mmol／L,本研究以LDL平均值為低密度脂蛋白基線水平,LDL水平與年齡呈負相關,相關性檢驗P0.05,呈顯著相關。說明伴隨年齡遞增LDL水平呈現(xiàn)明顯遞減趨勢,這可能與飲食攝入情況有一定聯(lián)系。痰濕阻遏型有270例,脾腎陽虛型有78例,肝腎陰虛型有95例,陰虛陽亢型有48例,氣滯血瘀型有71例。各證型平均年齡的分布總趨勢為：痰濕阻遏型陰虛陽亢型脾腎陽虛型肝腎陰虛型氣滯血瘀型。痰濕阻遏型患者無論是在數(shù)量上還是平均年齡上都超過其余證型,可能是因為老年患者正氣虧虛,臟腑功能衰退,水液輸布障礙,不能化氣生津,而致痰濁。肝腎陰虛和陰虛陽亢的患者LDL平均值較其他證型高,但通過統(tǒng)計學分析各中醫(yī)證型LDL水平的分布無明顯的不同,這可能是由于本調(diào)查研究的樣本量較少,不能說明LDL水平與中醫(yī)證候之間的相關性。結論：1.562例老年患者LDL平均值為2.9076±0.74492mmol/L,這與國內(nèi)部分地區(qū)老年患者LDL基線水平的研究調(diào)查結果基本相似,與美國及部分歐洲國家老年患者LDL基線水平的調(diào)查結果相比較低,因此這個結果對于完善安全有效的老年人降脂治療方案有一定意義。2.本研究發(fā)現(xiàn)60～69歲老年患者低密度脂蛋白平均值較70歲以上老年人的要高,隨著年齡的增長,LDL平均值呈遞減趨勢,根據(jù)本研究LDL在各年齡段分布情況可發(fā)現(xiàn)隨著年齡遞增LDL水平也呈現(xiàn)明顯遞減趨勢。3.老年患者中痰濕阻遏證較為常見,可能由于老年人正氣虧虛,臟腑功能衰退,水液輸布障礙,化氣生津不利,易生痰濁。
[Abstract]:Objective: to explore the baseline level of low density lipoprotein (LDL) in the elderly and to analyze the TCM syndromes in order to find out the baseline level of LDL and the distribution of TCM syndromes in order to provide a basis for optimizing the program of lipid reduction in the elderly in China. Methods: 562 elderly inpatients were randomly collected. According to the principle of looking, hearing, asking and cutting, TCM syndrome differentiation was carried out by engraving the syndrome and tongue pulse, and referring to the guiding principles of Clinical Research of New Chinese Medicine (trial) (2002). The results of LDL examination were recorded. All the data are counted by SPSS20.0 software. The methods used are chi-square test, single factor analysis of variance, correlation analysis and so on. Results among the 562 elderly patients, the youngest was 60 years old, the oldest was 94 years old, the average age was 72.61 鹵9.462 years, and the age group was 6069 years old and 70 to 79 years old. The mean value of LDL 鈮，

本文編號：2146401