【摘要】：目的:本研究通過觀察患者的相關(guān)臨床指標,探究2型糖尿病血瘀證型微血管并發(fā)癥的發(fā)生與血細胞參數(shù)之間的關(guān)系。為2型糖尿病血瘀證的辨證提供客觀指標,并提供早期預防、治療糖尿病及微血管并發(fā)癥的思路。材料與方法:選用與納入標準相符的2型糖尿病血瘀證患者178例,依據(jù)排除標準及剔除標準除去19例,最終研究病例159例。以是否存在微血管并發(fā)癥的發(fā)生為依據(jù)進行分組,即微血管并發(fā)癥組和無并發(fā)癥組。搜集并記錄患者的基本情況,如性別、年齡、病程。入院后第一次的血常規(guī)(紅細胞壓積、紅細胞平均體積、紅細胞分布寬度、血小板計數(shù)、血小板壓積、血小板平均體積)。選用SPSS17.0軟件進行統(tǒng)計解析,計數(shù)資料采用X2檢驗,計量資料采用單因素方差分析檢驗。進行初步相關(guān)性分析。結(jié)果:1.在收集的159個病例中,微血管并發(fā)癥組與無并發(fā)癥組相對照,兩組年齡、病程有差異(P0.05),具有可比性;性別無差異(P0.05)。2.在紅細胞參數(shù)方面,微血管并發(fā)癥組紅細胞壓積(HCT)較高,與無并發(fā)癥組相對照,具有統(tǒng)計學意義(P0.05);紅細胞平均體積(MCV)、紅細胞分布寬度(RDW)均比無并發(fā)癥組高,且差異具有統(tǒng)計學意義(P0.05)。3.在血小板參數(shù)方面,微血管并發(fā)癥組的血小板計數(shù)(PLT)和血小板壓積(PCT)較無并發(fā)癥組降低,但兩者相比較沒有統(tǒng)計學差異(P0.05);并發(fā)癥組的血小板平均體積(MPV)與無并發(fā)癥組相比較有所升高,且具有統(tǒng)計學意義(P0.05)。結(jié)論:1.2型糖尿病血瘀證微血管并發(fā)癥的發(fā)生與年齡、病程相關(guān)聯(lián);與性別無關(guān)聯(lián)。2.2型糖尿病血瘀證微血管并發(fā)癥的發(fā)生與紅細胞壓積、紅細胞平均體積、紅細胞分布寬度具有相關(guān)性。3.2型糖尿病血瘀證微血管并發(fā)癥的發(fā)生與血小板平均體積有關(guān);與血小板壓積、血小板計數(shù)無關(guān)聯(lián)。
[Abstract]:Objective: to investigate the relationship between blood cell parameters and microvascular complications in type 2 diabetes mellitus. To provide objective indexes for differentiation of blood stasis syndrome in type 2 diabetes mellitus, and to provide early prevention and treatment of diabetes mellitus and microvascular complications. Materials and methods: 178 cases of type 2 diabetes mellitus with blood stasis syndrome were selected according to the inclusion criteria. 19 cases were removed according to the exclusion criteria and the exclusion criteria. 159 cases were finally studied. According to the occurrence of microvascular complications, they were divided into two groups: microvascular complication group and no complication group. Collect and record the patient's basic information, such as gender, age, course of disease. The first blood routine after admission (hematocrit, mean erythrocyte volume, erythrocyte distribution width, platelet count, platelet hematocrit, mean platelet volume). SPSS 17.0 software was used for statistical analysis, X2 test was used for counting data, and single factor analysis of variance test was used for measurement data. Preliminary correlation analysis was carried out. The result is 1: 1. In 159 cases collected, microvascular complications group and no complications group compared, the two groups of age, course of disease were different (P0.05), comparable; gender no difference (P0.05). 2. In terms of erythrocyte parameters, hematocrit (HCT) in microvascular complication group was higher than that in no complication group (P0.05), mean erythrocyte volume (MCV) and erythrocyte distribution width (RDW) were higher than those in no complication group. The difference was statistically significant (P0.05). Platelet count (PLT) and platelet pressure-product (PCT) in microvascular complications group were lower than those in non-complication group. However, there was no statistical difference between the two groups (P0.05); the mean platelet volume (MPV) in the complication group was higher than that in the non-complication group (P0.05). Conclusion the occurrence of microvascular complications in type 1.2 diabetes mellitus with blood stasis syndrome is related to age and course of disease, and there is no correlation between microvascular complications and hematocrit and mean volume of erythrocyte in type 2.2 diabetes mellitus with blood stasis syndrome. The occurrence of microvascular complications in type 3.2 diabetic blood stasis syndrome was related to the mean volume of platelets, but not to platelet compactness and platelet count.
【學位授予單位】：遼寧中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R259
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本文編號：2130064