疏肝解郁安神法治療心臟神經(jīng)癥（氣滯濕阻證）的臨床研究
發(fā)布時(shí)間：2018-07-17 07:40
【摘要】：目的:通過臨床病例分析,觀察疏肝解郁安神法治療心臟神經(jīng)癥(氣滯濕阻證)的臨床療效。方法:采用臨床隨機(jī)、對照觀察的方法,對2014年4月至2015年10月在長春中醫(yī)藥大學(xué)第一附屬醫(yī)院心內(nèi)科姜麗紅教授門診就診,并明確診斷為心臟神經(jīng)癥(氣滯濕阻證)的患者72例,剔除脫落者作為臨床觀察對象,隨機(jī)分成2組,實(shí)驗(yàn)組36例給予疏肝解郁安神法中藥湯劑口服,對照組36例給予逍遙散湯劑口服。以14天為一個(gè)療程,連續(xù)治療2個(gè)療程,隨訪一個(gè)月,觀察并采集治療前、后每個(gè)患者詳細(xì)的臨床癥狀、HAMA評分等變化,之后采用SPSS16.0軟件將各個(gè)研究對象的評分?jǐn)?shù)據(jù)錄入數(shù)據(jù)庫,采用統(tǒng)計(jì)描述,t檢驗(yàn)等方法,評價(jià)疏肝解郁安神法對心臟神經(jīng)癥的臨床療效。結(jié)果:兩組患者用藥前年齡、性別、病程、肝腎功能基數(shù)比較,P0.05,組間無差異,無統(tǒng)計(jì)學(xué)意義,具有可比性;用藥前2組HAMA評分比較,經(jīng)t檢驗(yàn)P=0.5350.05,無統(tǒng)計(jì)學(xué)意義,具有可比性;用藥前心臟神經(jīng)癥軀體化量表SSS評分比較,經(jīng)卡方檢驗(yàn),P=0.990.05,無統(tǒng)計(jì)學(xué)意義,具有可比性;用藥前2組中醫(yī)證候評分比較,經(jīng)t檢驗(yàn)P=0.4250.05,無統(tǒng)計(jì)學(xué)意義,具有可比性;用藥后2組HAMA評分明顯下降,用藥后組內(nèi)比較P=0.000.05,兩組組內(nèi)比較均有顯著差異,有統(tǒng)計(jì)學(xué)意義,用藥后均明顯優(yōu)于用藥前;用藥后組間比較,P=0.0190.05,存在顯著差異,有統(tǒng)計(jì)學(xué)意義,治療組明顯優(yōu)于對照組;用藥后兩組中醫(yī)證候評分組間與組內(nèi)比較,P0.05,均有顯著差異,有統(tǒng)計(jì)學(xué)意義,用藥后明顯優(yōu)于用藥前、治療組明顯優(yōu)于對照組;用藥后兩組心臟神經(jīng)癥SSS評分比較,P=0.0130.05,存在顯著差異,有統(tǒng)計(jì)學(xué)意義。綜上,疏肝解郁安神法治療心臟神經(jīng)癥(氣滯濕阻證)在臨床上療效顯著,用藥前后比較、用藥后組間比較均有差異(P0.05),其治療組臨床療效明顯優(yōu)于對照組。結(jié)論:采用疏肝解郁安神法治療心臟神經(jīng)癥,能明顯降低HAMA評分、中醫(yī)癥候療效評分以及軀體化量表SSS評分;疏肝解郁安神法對心臟神經(jīng)癥(氣滯濕阻證)的臨床療效顯著,治療組明顯優(yōu)于對照組,此臨床研究有意義。
[Abstract]:Objective: to observe the clinical effect of soothing the liver and relieving depression and soothing the mind in treating cardiac neurosis (qi stagnation and dampness obstruction syndrome) by clinical case analysis. Methods: from April 2014 to October 2015, Professor Jiang Lihong, Department of Cardiology, first affiliated Hospital of Changchun University of traditional Chinese Medicine, was enrolled in this study. 72 cases of cardiac neurosis (Qi stagnation and dampness obstruction syndrome) were definitely diagnosed and were randomly divided into 2 groups. 36 cases in the experimental group were treated with traditional Chinese medicine decoction of soothing the liver and relieving depression and tranquilizing the spirit. 36 cases of control group were given Xiaoyao Powder decoction orally. After 14 days as a course of treatment, 2 consecutive courses of treatment were followed up for one month, the changes of Hama scores of each patient were observed and collected before and after the treatment, and then the score data of each patient were entered into the database by SPSS 16.0 software. To evaluate the clinical efficacy of the method of soothing liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis by means of statistical description test. Results: there was no difference between the two groups in age, sex, course of disease, liver and kidney function cardinal number (P0.05), there was no difference between the two groups, there was no significant difference in Hama score between the two groups before medication, and there was no statistical significance and comparability between the two groups after t test (P0. 5350.05). The comparison of SSS score of cardiac neurosis somatization scale before medication was not statistically significant and comparable by chi-square test (P0. 990.05), and the comparison of TCM syndromes score between the two groups before medication was not statistically significant and comparable by t test (P0. 4250. 05). The Hama score of the two groups decreased obviously after the treatment, and the comparison between the two groups was 0.000.05. there was significant difference between the two groups, there was significant difference between the two groups, and the difference between the two groups was obviously better than that before the treatment, and there was a significant difference between the two groups after the use of the drug, there was significant difference between the two groups, and there was a significant difference between the two groups. The treatment group was significantly better than the control group, the two groups after the treatment of TCM syndrome scores between the group and the group compared with P0.05, there was significant difference, there was statistical significance, the treatment group was significantly better than before medication, the treatment group was significantly better than the control group. The SSS score of cardiac neurosis in the two groups was significantly higher than that in the control group (P < 0. 0130. 05). To sum up, the method of soothing the liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) has a significant clinical effect, the comparison before and after the treatment, the comparison between the groups after medication have differences (P0.05), the clinical efficacy of the treatment group is significantly better than that of the control group. Conclusion: the treatment of cardiac neurosis with the method of soothing the liver and relieving the depression and tranquilizing the mind can obviously reduce the score of Hama, the curative effect of TCM and the score of SSS of somatization, and the clinical effect of the method of soothing the liver and relieving the depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) is remarkable. The treatment group is obviously superior to the control group, this clinical study is meaningful.
【學(xué)位授予單位】：長春中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R277.7
本文編號：2129634
[Abstract]:Objective: to observe the clinical effect of soothing the liver and relieving depression and soothing the mind in treating cardiac neurosis (qi stagnation and dampness obstruction syndrome) by clinical case analysis. Methods: from April 2014 to October 2015, Professor Jiang Lihong, Department of Cardiology, first affiliated Hospital of Changchun University of traditional Chinese Medicine, was enrolled in this study. 72 cases of cardiac neurosis (Qi stagnation and dampness obstruction syndrome) were definitely diagnosed and were randomly divided into 2 groups. 36 cases in the experimental group were treated with traditional Chinese medicine decoction of soothing the liver and relieving depression and tranquilizing the spirit. 36 cases of control group were given Xiaoyao Powder decoction orally. After 14 days as a course of treatment, 2 consecutive courses of treatment were followed up for one month, the changes of Hama scores of each patient were observed and collected before and after the treatment, and then the score data of each patient were entered into the database by SPSS 16.0 software. To evaluate the clinical efficacy of the method of soothing liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis by means of statistical description test. Results: there was no difference between the two groups in age, sex, course of disease, liver and kidney function cardinal number (P0.05), there was no difference between the two groups, there was no significant difference in Hama score between the two groups before medication, and there was no statistical significance and comparability between the two groups after t test (P0. 5350.05). The comparison of SSS score of cardiac neurosis somatization scale before medication was not statistically significant and comparable by chi-square test (P0. 990.05), and the comparison of TCM syndromes score between the two groups before medication was not statistically significant and comparable by t test (P0. 4250. 05). The Hama score of the two groups decreased obviously after the treatment, and the comparison between the two groups was 0.000.05. there was significant difference between the two groups, there was significant difference between the two groups, and the difference between the two groups was obviously better than that before the treatment, and there was a significant difference between the two groups after the use of the drug, there was significant difference between the two groups, and there was a significant difference between the two groups. The treatment group was significantly better than the control group, the two groups after the treatment of TCM syndrome scores between the group and the group compared with P0.05, there was significant difference, there was statistical significance, the treatment group was significantly better than before medication, the treatment group was significantly better than the control group. The SSS score of cardiac neurosis in the two groups was significantly higher than that in the control group (P < 0. 0130. 05). To sum up, the method of soothing the liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) has a significant clinical effect, the comparison before and after the treatment, the comparison between the groups after medication have differences (P0.05), the clinical efficacy of the treatment group is significantly better than that of the control group. Conclusion: the treatment of cardiac neurosis with the method of soothing the liver and relieving the depression and tranquilizing the mind can obviously reduce the score of Hama, the curative effect of TCM and the score of SSS of somatization, and the clinical effect of the method of soothing the liver and relieving the depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) is remarkable. The treatment group is obviously superior to the control group, this clinical study is meaningful.
【學(xué)位授予單位】：長春中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R277.7
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