本文選題：原發(fā)性膽汁反流性胃炎 + 肝氣犯胃證　； 參考：《黑龍江中醫(yī)藥大學》2017年碩士論文

【摘要】：研究目的:通過運用疏肝和胃降逆法對原發(fā)性膽汁反流性胃炎(肝氣犯胃證)的治療,探討其臨床療效。研究方法:選擇符合原發(fā)性膽汁反流性胃炎(肝氣犯胃證型)患者50例,均在2016年1月至2017年1月就診于黑龍江中醫(yī)藥大學附屬第一醫(yī)院門診,入選50例患者給予疏肝和胃降逆法(主要藥物組成:醋炙柴胡、枳殼、炒白術(shù)、厚樸、金錢草等)進行治療,將藥物加水約400毫升,浸泡1小時,煎15-20分鐘,取汁;二煎加水400毫升,取汁;二煎混合,分早晚飯前兩次溫服,連服8周。8周后進行治療前后對照,觀察患者的臨床療效、癥狀積分、胃鏡的變化,對結(jié)果進行統(tǒng)計學分析。結(jié)果:疏肝和胃降逆法對原發(fā)性膽汁反流性胃炎(肝氣犯胃證)的治療,臨床總有效率為91.49%,治療胃黏膜相的總有效率是93.61%,治療膽汁返流的總有效率是95.74%,中醫(yī)證候總有效率是91.49%。在中醫(yī)證候總積分方面,治療后較治療前顯著下降(P0.01)。在中醫(yī)證候單項積分方面,治療后在患者胃痛或痛竄兩脅;胃脘痞滿;情志不暢;反酸、燒心;口苦、口臭;惡心、嘔吐;噯氣、善太息;厭油膩;脘悶;大便干結(jié)方面,積分均較治療前有所下降,有統(tǒng)計學差異(P0.01)。結(jié)論:1、疏肝和胃降逆法能夠改善原發(fā)性膽汁反流性胃炎(肝氣犯胃證型)患者的中醫(yī)證候表現(xiàn)。2、疏肝和胃降逆法能夠改善原發(fā)性膽汁反流性胃炎(肝氣犯胃證型)患者的胃鏡下炎癥病變和膽汁反流情況。
[Abstract]:Objective: to investigate the clinical effect of primary bile reflux gastritis (GG) by using the method of soothing the liver and lowering the stomach. Methods: a total of 50 patients with primary bile reflux gastritis (liver qi and stomach syndrome) were selected from January 2016 to January 2017 in the outpatient clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. 50 patients were treated with the methods of soothing the liver and lowering the inverse of stomach (the main drug composition: Chaihu, Fructus Aurantii, Atractylodes macrocephala, Magnolia officinalis, Atractylodes macrocephala, etc.). The drug was added with water for about 400 ml, soaked for 1 hour, fried for 15-20 minutes, and the juice was taken. Two decoction plus water 400 ml, two decoction mixed, two times warm clothes before early supper, 8 weeks after 8 weeks of treatment, observed the clinical efficacy, symptom score, changes of gastroscope, statistical analysis of the results. Results: the clinical effective rate of primary bile reflux gastritis was 91.49, the total effective rate of treating gastric mucosa was 93.61, the total effective rate of treating bile regurgitation was 95.74 and the total effective rate of TCM syndrome was 91.49. In TCM syndromes total integral, after treatment than before treatment significantly decreased (P0.01). In the single integral of TCM syndromes, after treatment, there are two sides in the patients' stomach pain or pain channeling; epigastric fullness; unobstructed mood; regurgitation, heartburn; bitter mouth, bad breath; nausea, vomiting; belching, good breath; anaerobic greasy; epigastric tightness; stool dryness; The scores were significantly lower than those before treatment (P 0.01). Conclusion the methods of relieving liver and lowering stomach inversion can improve the symptoms of traditional Chinese medicine syndrome of primary bile reflux gastritis (liver qi invading stomach syndrome type), and soothing liver and stomach descending method can improve primary bile reflux gastritis (liver qi invading stomach syndrome type). Inflammation and bile regurgitation under gastroscopy.
【學位授予單位】：黑龍江中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R259

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