發(fā)布時(shí)間：2018-06-25 23:39

  本文選題：出血性中風(fēng)后輕度認(rèn)知功能損害 + 破血化瘀、填精補(bǔ)髓　； 參考：《長(zhǎng)春中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:通過臨床研究,評(píng)價(jià)破血化瘀、填精補(bǔ)髓法治療出血性中風(fēng)后輕度認(rèn)知功能損害的臨床療效。方法:篩選符合出血性中風(fēng)后輕度認(rèn)知功能損害診斷的患者72例,隨機(jī)分為兩組,治療組采用中藥治療方案,對(duì)照組給予尼莫地平片,療程均為3個(gè)月。應(yīng)用認(rèn)知評(píng)定量表和中醫(yī)核心癥狀觀察量表評(píng)價(jià)兩組治療效果。結(jié)果:1.治療3個(gè)月后,中藥治療組與對(duì)照組總療效(ADAS-cog、中醫(yī)核心癥狀)在總有效率和顯效率方面,兩組比較具有明顯差異(P0.05)。2.在改善ADAS-cog積分比較上,治療組組內(nèi)比較有顯著性差異(P0.05),對(duì)照組有明顯差異(P0.05),兩組組間比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。3.在中醫(yī)核心癥狀總積分比較上,治療組組內(nèi)比較有顯著性差異(P0.05),對(duì)照組無(wú)明顯差異(P0.05),兩組組間比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。提示中藥治療組在改善患者ADAS-cog與中醫(yī)核心癥狀積分方面均有療效,明顯優(yōu)于對(duì)照組。結(jié)論:1.破血化瘀填精補(bǔ)髓法能夠有效改善出血性中風(fēng)后輕度認(rèn)知功能損害患者的認(rèn)知水平。2.破血化瘀填精補(bǔ)髓法能夠有效改善出血性中風(fēng)后輕度認(rèn)知功能損害患者的臨床癥狀,其中主要包括記憶力障礙(言談不知首尾,轉(zhuǎn)盼遺忘,思量不能等)、言語(yǔ)障礙(言善誤,言語(yǔ)懶,多言不定,言語(yǔ)如凝、言語(yǔ)重復(fù)等)、情感障礙(居暗避人,興趣索然,憂愁思慮等)及肢體障礙(肢體笨拙,步履遲重)。
[Abstract]:Objective: to evaluate the clinical effect of breaking blood and removing blood stasis and filling essence and reinforcing marrow in the treatment of mild cognitive impairment after hemorrhagic apoplexy. Methods: a total of 72 patients with mild cognitive impairment after hemorrhagic stroke were selected and randomly divided into two groups: the treatment group was treated with traditional Chinese medicine and the control group was given nimodipine tablets for 3 months. The therapeutic effects of the two groups were evaluated by using the cognitive rating scale and the observation scale of the core symptoms of traditional Chinese medicine. The result is 1: 1. After 3 months of treatment, the total efficacy (ADAS-cog) of the Chinese medicine treatment group and the control group (ADAS-cog) in the total effective rate and effective rate, there was significant difference between the two groups (P0.05). 2. In improving ADAS-cog score comparison, the treatment group has significant difference (P0.05), the control group has a significant difference (P0.05), the comparison between the two groups has statistical significance (P0.05). 3. On the total integral comparison of TCM core symptoms, the treatment group had significant difference (P0.05), the control group had no significant difference (P0.05), the difference between the two groups was statistically significant (P0.05). The results suggest that the treatment group has better effect than the control group in improving ADAS-cog and the score of core symptoms of TCM. Conclusion 1. The method of breaking blood and removing blood stasis and filling up marrow can effectively improve the cognitive level of patients with mild cognitive impairment after hemorrhagic apoplexy. The method of breaking blood and removing blood stasis and filling essence and nourishing marrow can effectively improve the clinical symptoms of patients with mild cognitive impairment after hemorrhagic stroke, which mainly include memory disorder (talking without knowing the beginning and end, turning to oblivion, thinking, etc.), speech disorder (good speech, false speech, etc.) Sloth, indeterminacy, speech, repetition, etc.), emotional disorders (avoidance, lack of interest, anxiety, etc.) and physical disorders (clumsy limbs, late steps).
【學(xué)位授予單位】：長(zhǎng)春中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R277.7

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 韓征宇;李光來;;丁苯酞對(duì)血管性認(rèn)知障礙患者認(rèn)知功能的改善作用[J];臨床醫(yī)藥實(shí)踐;2016年02期

2 李萌;王宏;王茂松;;血清Aβ1-42濃度與缺血性卒中后認(rèn)知障礙的相關(guān)性研究[J];中國(guó)現(xiàn)代醫(yī)藥雜志;2016年01期

3 劉霄霄;鄭健剛;劉濤;;針?biāo)幗Y(jié)合治療瘀血阻絡(luò)型腦梗死后輕度認(rèn)知障礙的臨床觀察[J];針灸臨床雜志;2015年12期

4 劉石梅;吳小慧;蔡思敏;李顯q;段新;趙敖;;血管性癡呆患者認(rèn)知功能與血漿同型半胱氨酸水平的關(guān)系[J];中國(guó)臨床新醫(yī)學(xué);2015年11期

5 馮曉強(qiáng);夏從羊;張峰;湯群峰;;出血性血管性癡呆患者磁敏感成像[J];中國(guó)老年學(xué)雜志;2015年10期

6 張憲忠;高磊;焦靜;隋曉琳;宋衛(wèi);牟善茂;馬汝華;張?jiān)蕩X;;復(fù)方蓯蓉益智膠囊對(duì)中風(fēng)后輕度認(rèn)知障礙患者腦血流及血管內(nèi)皮功能的影響研究[J];世界中西醫(yī)結(jié)合雜志;2015年04期

7 趙奕;許能貴;孫健;徐振華;邸富榮;黃康柏;;通督調(diào)神針刺法治療血管性輕度認(rèn)知障礙的臨床療效[J];中國(guó)老年學(xué)雜志;2014年23期

8 毛高峰;李朝武;聶海嶺;黎逢光;成勇;林培s，

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