發(fā)布時(shí)間：2018-06-19 11:47

  本文選題：脊柱結(jié)核 + 抗結(jié)核膠囊��； 參考：《廣西中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:觀察抗結(jié)核膠囊配合一線抗結(jié)核西藥治療寒凝血瘀型脊柱結(jié)核的臨床療效,評(píng)價(jià)中藥抗結(jié)核膠囊的有效性,為在臨床中推廣應(yīng)用提供依據(jù)。方法:研究方法采用隨機(jī)對(duì)照的方法,選擇2014年10月—2015年6月廣西中醫(yī)藥大學(xué)附屬瑞康醫(yī)院和廣西中醫(yī)藥大學(xué)第一附屬醫(yī)院脊柱科收治的門診及住院確診患者60例,采用簡(jiǎn)單隨機(jī)分組方法,病例隨機(jī)分為治療組和對(duì)照組,兩組各30例,治療組選擇口服本院制劑“抗結(jié)核膠囊”,并配合當(dāng)前一線抗結(jié)核西藥治療,對(duì)照組僅選擇當(dāng)前一線抗結(jié)核西藥治療,西藥抗結(jié)核均按照標(biāo)準(zhǔn)療法。分別在治療足療程后進(jìn)行療效評(píng)定,觀察記錄兩組實(shí)驗(yàn)室檢查、視覺(jué)疼痛模擬評(píng)分(VAS)、平均疼痛時(shí)間等結(jié)果,并進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:入選60例確診患者均完成了整個(gè)治療過(guò)程,無(wú)一例脫落。經(jīng)統(tǒng)計(jì)學(xué)分析,治療組和對(duì)照組入選病例中,患者年齡、性別、病情等方面無(wú)明顯統(tǒng)計(jì)學(xué)差異(P0.05),無(wú)統(tǒng)計(jì)學(xué)意義;治療足療程后,治療組在降低紅細(xì)胞血沉率(ESR)、緩解疼痛、縮短疼痛時(shí)間方面,與對(duì)照組相比有明顯差異(P0.05),有統(tǒng)計(jì)學(xué)意義;在藥物對(duì)肝腎功能損傷方面,兩組對(duì)比統(tǒng)計(jì)無(wú)明顯差異(P0.05),無(wú)統(tǒng)計(jì)學(xué)意義。治療組在治療過(guò)程中未出現(xiàn)嚴(yán)重藥物毒副作用。結(jié)論:中藥抗結(jié)核膠囊配合一線抗結(jié)核西藥治療寒凝血瘀型脊柱結(jié)核較單純一線抗結(jié)核西藥治療,在降低血沉、緩解疼痛、減少疼痛時(shí)間方面有更明顯優(yōu)勢(shì),并且追加中醫(yī)藥抗結(jié)核膠囊后,沒(méi)有加重對(duì)肝腎功能的損傷,在治療中患者的依從性比較高,中藥抗結(jié)核膠囊配合一線抗結(jié)核西藥治療是一種在臨床上有效、方便、安全的中西醫(yī)結(jié)合治療方案,值得廣泛推廣和應(yīng)用。
[Abstract]:Objective: to observe the clinical effect of anti-tuberculosis capsule combined with first-line anti-tuberculosis western medicine in treating spinal tuberculosis with cold coagulation and blood stasis, and to evaluate the effectiveness of anti-tuberculosis capsule in order to provide the basis for clinical application. Methods: 60 outpatients and inpatients were selected from Ruikang Hospital affiliated to Guangxi University of traditional Chinese Medicine and Department of Spine of the first affiliated Hospital of Guangxi University of traditional Chinese Medicine from October 2014 to June 2015. The patients were randomly divided into treatment group (n = 30) and control group (n = 30). The control group only selected the current first-line anti-tuberculosis medicine treatment, western medicine anti-tuberculosis treatment according to the standard. The results of laboratory examination visual pain analogue score and average pain time were recorded and statistically analyzed. Results: all the 60 patients completed the whole treatment process, none of them dropped off. After statistical analysis, there was no significant difference in age, sex, condition of the patients between the treatment group and the control group (P 0.05), there was no statistical significance; after treatment, the erythrocyte sedimentation rate (ESR) was reduced and the pain was alleviated in the treatment group. Compared with the control group, there was a significant difference in pain time between the two groups (P 0.05), but there was no significant difference between the two groups in terms of liver and kidney function injury, there was no significant difference between the two groups. No serious side effects were observed in the treatment group. Conclusion: the combination of anti-tuberculosis capsule and first-line antituberculous medicine in the treatment of spinal tuberculosis with cold coagulation and blood stasis has more obvious advantages in reducing erythrocyte sedimentation rate, relieving pain and reducing pain time than that of single first-line anti-tuberculosis western medicine. After adding anti-tuberculosis capsule of traditional Chinese medicine, the injury to liver and kidney function was not aggravated, the compliance of patients was high in treatment. The combination of anti-tuberculosis capsule and first-line anti-tuberculosis medicine was effective and convenient in clinic. Safe treatment of integrated Chinese and western medicine, worthy of extensive promotion and application.
【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

【相似文獻(xiàn)】

相關(guān)期刊論文 前2條

1 張國(guó)棟;朱英斌;;抗結(jié)核膠囊治療難治性肺結(jié)核的研究[J];吉林醫(yī)學(xué);2008年15期

2 ;[J];;年期

相關(guān)碩士學(xué)位論文 前1條

1 張正浩;抗結(jié)核膠囊治療脊柱結(jié)核的療效觀察[D];廣西中醫(yī)藥大學(xué);2016年

，

本文編號(hào)：2039779