本文選題：金水相生 + 更年期綜合癥��； 參考：《廣州中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：背景:更年期綜合征(Climacteric syndrome,CMS)又稱圍絕經(jīng)期綜合征,是女性從中年逐漸進(jìn)入老年期的明顯標(biāo)志,也是婦女生理機(jī)能衰退的標(biāo)志,CMS是由于體內(nèi)性激素水平的波動(dòng)或減少導(dǎo)致的一系列癥狀,主要表現(xiàn)為軀體化癥狀及情志障礙,如月經(jīng)功能失調(diào)、潮熱、心慌心悸、焦躁不安、記憶力降低、少眠、喜怒無常等等,嚴(yán)重影響到廣大更年期婦女的生活質(zhì)量,并可增加心血管、骨質(zhì)疏松等多種并發(fā)癥的風(fēng)險(xiǎn),給社會(huì)增加了較大的負(fù)擔(dān)與壓力。目的:本研究主要觀察金水相生配穴法與普通配穴法治療腎陰虛型更年期婦女的綜合臨床療效,主要通過簡(jiǎn)單隨機(jī)對(duì)照原則,將60例患者分為兩組,治療組取穴如下:主穴(腎俞、肝俞、氣海、三陰交、神門、內(nèi)關(guān)、太沖)加上金水相生配穴(魚際、太淵、太溪、復(fù)溜),對(duì)照組取穴如下:主穴(同治療組)加上常規(guī)配穴(陰谷、照海),以觀察兩組患者的治療效果。研究中采用國(guó)際公認(rèn)的Kupperman Index評(píng)分量表(簡(jiǎn)稱KI指數(shù))及中醫(yī)癥候評(píng)分來記錄兩組患者的治療效果,觀察金水相生配穴法對(duì)比普通配穴方法在治療腎陰虛型圍絕經(jīng)期系列癥狀方面是否更具有優(yōu)越性,以便為臨床上治療本病探索更加高效的治療方法。研究方法:本次實(shí)驗(yàn)運(yùn)用簡(jiǎn)單隨機(jī)對(duì)照的原則,根據(jù)研究目的和受試對(duì)象的各個(gè)標(biāo)準(zhǔn),將符合標(biāo)準(zhǔn)的受試對(duì)象隨機(jī)分配為金水相生配穴法組與普通配穴法組各30例,共60例,每周針刺3次,隔天1次,8周為1療程,經(jīng)治療一療程后分別記錄中西醫(yī)評(píng)分量表,采用SPSS19.0軟件包統(tǒng)計(jì)分析收集數(shù)據(jù)。研究結(jié)果:1、治療前后KI指數(shù)療效評(píng)價(jià):經(jīng)過一療程的治療,兩組患者的KI指數(shù)相比治療之前都有明顯下降,對(duì)比兩組治療之后結(jié)果,P值0.05,兩組治療方法均存在明顯的統(tǒng)計(jì)學(xué)差異,結(jié)合二者的治療前后KI指數(shù)差值,說明治療組療效較對(duì)照組好。2、綜合臨床療效比較:KI指數(shù)經(jīng)過尼莫地平法計(jì)算后得出一下結(jié)果,治療組30例,經(jīng)過8周治療后,痊愈2例(6.7%),顯效21例(70%),有效6例(20%),無效1例(3.33%),總有效率為96.67%。對(duì)照組30例患者,經(jīng)過8周治療之后,痊愈 0 例(0.00%),顯效 21 例(70%),有效 7 例(23.330%),無效 2 例(6.67%),總有效率93.33%。治療組總有效率大于對(duì)照組,但經(jīng)Ridit分析后得出P0.05,無明顯的統(tǒng)計(jì)學(xué)差異。3、中醫(yī)癥候療效評(píng)價(jià):經(jīng)一療程治療,治療組和對(duì)照組各中醫(yī)癥狀積分較前都有所下降,將兩組經(jīng)治療之后評(píng)分各自行組內(nèi)配對(duì)秩和檢驗(yàn)后得出:除治療組陰部干澀癥狀P大于0.05,余各癥狀p值均小于0.05,故兩組治療均有效;將兩組間各癥狀行兩獨(dú)立樣本秩和檢驗(yàn)后得出烘熱汗出、少寐多夢(mèng)、陰部干澀三個(gè)癥狀的P值小于0.05,差異有統(tǒng)計(jì)學(xué)意義,據(jù)治療前后差值可得出結(jié)論:治療組在改善烘熱汗出、少寐多夢(mèng)方面優(yōu)于對(duì)照組,而在改善陰部干澀方面不如對(duì)照組;而腰膝酸痛或足跟痛、頭暈、五心煩熱、心悸、急躁易怒、口干、皮膚瘙癢p值均大于0.05,差異無統(tǒng)計(jì)學(xué)意義。故金水相生配穴法治療腎陰虛型更年期綜合癥,在烘熱汗出、少寐多夢(mèng)方面明顯優(yōu)于對(duì)照組。結(jié)論:金水相生配穴法與普通配穴方法在治療腎陰虛型CMS方面皆存在明顯療效,但在降低KI指數(shù)及中醫(yī)癥候的烘熱汗出、少寐多夢(mèng)兩方面,金水相生配穴法均明顯優(yōu)于普通配穴法,故金水相生配穴法治療腎陰虛型圍絕經(jīng)期綜合癥,尤其是在烘熱汗出、少寐多夢(mèng)明顯的患者更具優(yōu)越性,值得在臨床上進(jìn)一步推廣應(yīng)用。
[Abstract]:Background: Climacteric syndrome (CMS), also known as perimenopausal syndrome, is a marked sign of women's gradual entry into the aged from middle age. It is also a sign of the decline of the physiological function of women. CMS is a series of symptoms caused by the fluctuation or reduction of sex hormone levels in the body, mainly manifested in somatization symptoms and emotional disorders, such as Menstrual dysfunction, hot flashes, palpitation, restlessness, memory reduction, less sleep, and moody, etc., seriously affect the quality of life of the women in the menopause, and increase the risk of many complications such as cardiovascular and osteoporosis, and increase the burden and pressure on the society. Objective: This study mainly observed the combination of golden water and water. The comprehensive clinical effect of the method and the common acupoint method in the treatment of menopause women of kidney yin deficiency type, mainly through the simple random control principle, divided 60 patients into two groups. The treatment group took the following points as following: the main point (Shenshu, Gan Shu, Qi Hai, Sanyinjiao, Shenmen, Neiguan, Taijin) plus golden water matching acupoints (thenar, Taiyuan, Taiyuan, Fu slip), and the control group taking acupoints as follows: The treatment effect of the two groups of patients was observed in the main points (the same treatment group) with the conventional acupoints (Yin Valley and the sea) to observe the therapeutic effect of the two groups. In the study, the therapeutic effect of the two groups of patients was recorded by the internationally recognized Kupperman (abbreviation) scale (abbreviated KI index) and TCM syndrome score, and the golden water phase matching point method was compared with the common acupoint method in the treatment of kidney yin deficiency type circumference. Whether the menopause series of symptoms are more superior in order to explore more efficient treatment methods for the clinical treatment of the disease. There were 30 cases in each group, 60 cases were treated with acupuncture 3 times a week, 1 times a day and 8 weeks as 1 courses. After a course of treatment, the score of Chinese and Western medicine was recorded, and the data were collected by SPSS19.0 software package. The results were 1. After a course of treatment, the KI index of the two groups was compared with the treatment before treatment. Significantly decreased, compared the results of two groups after treatment, P value 0.05, two groups of treatment methods have obvious statistical differences, combined with the KI index difference before and after the treatment of two, indicating that the treatment group is better than the control group.2, comprehensive clinical efficacy comparison: KI index after nimodipine calculation, the result, 30 cases in the treatment group, after 8 weeks of treatment. After that, 2 cases (6.7%), 21 cases (70%), 6 cases (20%) and 1 cases (3.33%) were effective. The total effective rate was 30 patients in 96.67%. control group. After 8 weeks of treatment, 0 cases (0%) were cured, effective 21 cases (0%), invalid cases, total effective efficiency of 93.33%. treatment group were more effective than the control group, but after Ridit analysis, the total effective rate was higher than that of the control group, but after Ridit analysis, the total effective rate was higher than that of the control group. P0.05, there was no significant difference in statistics.3, traditional Chinese medicine syndrome effect evaluation: after a course of treatment, the treatment group and the control group all the symptoms of TCM symptoms were lower than before, the two groups after the treatment scores of each group in the paired rank and test after the treatment group, except for the treatment group of the perineum dry and astringent symptoms P more than 0.05, the remaining symptoms of the p value are less than 0.05, so two Group treatment was effective, the two groups of the symptoms of two independent samples of the rank sum test to get hot sweat out, less sleep dream, the P value of the perineum dry three symptoms less than 0.05, the difference is statistically significant, according to the difference before and after treatment can be concluded that the treatment group is better than the control group in improving the baking sweat, less dream and more dream, and in improving the perineum dry. It is not as good as the control group; while the waist and knee pain or heel pain, dizziness, five heart trouble heat, palpitation, irritability, dry mouth, and skin pruritus p value are more than 0.05, the difference is not statistically significant. Therefore, the golden water matching point method is obviously superior to the control group in the treatment of kidney yin deficiency type menopause syndrome. In the treatment of kidney yin deficiency type CMS, there is a significant effect in the treatment of kidney yin deficiency type, but in the two aspects of reducing the KI index and the hot sweat out of the syndrome of traditional Chinese medicine and less dream, the golden water phase matching acupoint method is obviously superior to the common acupoint method. Therefore, the golden water phase matching acupoint method is used to treat the kidney yin deficiency syndrome, especially in the hot sweat and less dream. Obvious patients have more advantages, which is worthy of further application in clinic.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R246.3

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