本文選題：非糜爛性反流病 + 統(tǒng)計學方法��； 參考：《北京中醫(yī)藥大學》2017年碩士論文

【摘要】：研究意義和目的:中醫(yī)在辨證治療非糜爛性反流病具有獨特的優(yōu)勢,而辨證治療的關鍵是對證候?qū)W有明確的認識,因此對本病的證候?qū)W研究就顯得至關重要了。本課題在中醫(yī)理論知識的指導下,通過對本病的文獻研究、流行病學及證候?qū)W調(diào)查,運用多元統(tǒng)計學的方法對本病的證型及證候要素分布特征進行探討,并分析了本病可能的病因病機,為本病的辨證論治及科研提供參考依據(jù)。研究方法:本研究將所收集277例非糜爛性反流病患者的數(shù)據(jù)資料(包括一般資料、中醫(yī)證候信息)錄入Excel表格,建立數(shù)據(jù)庫,使用SPSS21.0軟件進行統(tǒng)計分析;一般資料、疾病危險因素采用描述統(tǒng)計及描述推斷;中醫(yī)證候信息采用多元統(tǒng)計學方法,以研究本病常見的證候分布特征及病因病機。研究結(jié)果:1、一般資料結(jié)果:本次調(diào)查研究共收集277例NERD患者一般資料與四診信息,其中年齡最小者19歲,年齡最大者75歲,平均年齡48.49±13.134歲,中位年齡為51歲;男性93例,女性184例。對所收集數(shù)據(jù)進行統(tǒng)計分析:①發(fā)病年齡段特點:以青年組及中年組發(fā)病率最高,分別占38%和39%;②發(fā)病性別特點:女性發(fā)病率高于男性,男女比例為0.51:1,其中中老年女性發(fā)病率明顯高于男性;③發(fā)病體重特點:以體重正常者居多,約占55%;④發(fā)病職業(yè)特點:離退休及無業(yè)者偏多(44%),其次分別為行政及管理人員、商業(yè)及服務業(yè)、私營及個體工商,發(fā)病率分別為17%、15%和14%;⑤發(fā)病飲食特點:以油膩高脂肪(26%)、濃茶(14%)、辛辣(13%)等食物居多;⑥發(fā)病精神心理狀態(tài)特點:異常心理狀態(tài)患者比例占76%,其中,急躁易怒出現(xiàn)頻率最高,占38.63%;⑦發(fā)病季節(jié)特點:以春季(37%)為主;⑧發(fā)病與HP感染:HP感染陽性的陽性率為82%。2、在中醫(yī)證候方面:①主要癥狀:以反酸(91%)和燒心(84%)為主;②病位:主要在肝與胃,與脾、心、肺、膽等有一定的相關性;③病性:有虛實之分,虛者可見到氣虛、陽虛,實證者可見到痰濁、食積、濕熱、瘀血;④證型分布:可將本病大致分為五型:類濕熱內(nèi)蘊證、類痰瘀內(nèi)阻證、類肝胃郁熱證、類脾胃虛寒證、類肝胃不和證。研究結(jié)論:1、NERD患者以中青年為主;女性發(fā)病高于男性;發(fā)病與情緒、季節(jié)、HP感染等因素有關,與體重、飲食規(guī)律、睡眠質(zhì)量未觀察到明確相關性;2、中醫(yī)證候方面:NERD患者以反酸、燒心為主要癥狀;病位:本病的主要病位證素在肝與胃,與脾、心、肺、膽等有一定的相關性;病性:有虛實之分,虛者可見到氣虛、陽虛;實證者可見到痰濁、食積、濕熱、瘀血;證型分布:可將本病大致分為五型:類濕熱內(nèi)蘊證、類痰瘀內(nèi)阻證、類肝胃郁熱證、類脾胃虛寒證、類肝胃不和證。
[Abstract]:Research significance and objective: TCM has a unique advantage in the treatment of non-erosive reflux disease, and the key of dialectical treatment is to have a clear understanding of syndromes, so it is very important to study the syndromes of this disease. Under the guidance of traditional Chinese medicine theory knowledge, through the literature research, epidemiology and syndromes investigation of the disease, using the method of multivariate statistics to discuss the distribution characteristics of syndrome types and syndromes elements of the disease. The possible etiology and pathogenesis of this disease are analyzed to provide reference for syndrome differentiation and scientific research. Methods: the data of 277 patients with non-erosive reflux disease (including general information, TCM syndrome information) were recorded in Excel form, database was established, and SPSS21.0 software was used for statistical analysis. The disease risk factors were described and inferred, and the information of TCM syndromes were analyzed by multivariate statistical method to study the characteristics of syndromes distribution, etiology and pathogenesis of the disease. Results: in this study, we collected information of 277 NERD patients. The youngest was 19 years old, the oldest was 75 years old, the average age was 48.49 鹵13.134 years, the median age was 51 years old. 184 women. Statistical analysis of the collected data showed that the incidence rate in the youth group and middle age group was the highest, accounting for 38% and 39%, respectively. The incidence rate of female was higher than that of male. The male / female ratio was 0.51: 1, of which the incidence rate of elderly women was significantly higher than that of males. Most of them were of normal weight, accounting for about 55 / 4 of the occupational characteristics of the disease. The number of retired and unemployed persons was 44%, followed by administrative and managerial staff, respectively. In business and service industry, private and individual business, the incidence rate was 17% and 14%, respectively. The most common dietary characteristics were fatty and fatty food (26%), thick tea (14%), spicy tea (13%) and so on. (6) characteristics of psychosomatic state: the proportion of patients with abnormal mental state accounted for 76g. Among them, the frequency of irritability and irritability was the highest, accounting for 38.63% of the onset season: spring was the main part of the disease. (8) the positive rate of HP infection was 82.2in TCM syndrome, the main symptoms of 1: 1 were as follows: regurgitation 91C) and heart-burning 84.The main diseases were liver and stomach, spleen, heart, lung, gallbladder and so on, and there was certain correlation between liver and stomach, heart, lung, gallbladder and so on. 3 the distribution of the four syndrome types: deficiency, deficiency of qi, yang, phlegm, accumulation of food, dampness and heat, and blood stasis: the disease can be divided into five types: dampness and heat accumulation, phlegm and stasis internal obstruction, liver and stomach stagnation, and liver and stomach stagnation, respectively, which are classified into five types: internal dampness and heat accumulation syndrome, phlegm and stasis internal obstruction syndrome, liver and stomach stagnation heat syndrome, and so on. Type spleen and stomach deficiency cold syndrome, like liver and stomach disharmony syndrome. Conclusion the patients with NERD were mainly middle and young people; the incidence of female was higher than that of male; the incidence of disease was related to mood, infection of HP in season and so on, but there was no clear correlation with body weight, diet rule, sleep quality and so on. Heart burning is the main symptom; disease position: the main syndromes of this disease are related to the liver and stomach, spleen, heart, lung, gallbladder, etc.; the disease: there are deficiency, deficiency can see Qi deficiency, Yang deficiency; the positivist can see phlegm turbid, food accumulation, dampness and heat, etc. Blood stasis; Syndrome distribution: the disease can be divided into five types: dampness and heat accumulation syndrome, phlegm and blood stasis syndrome, liver and stomach stagnation syndrome, spleen and stomach deficiency cold syndrome, liver and stomach disharmony syndrome.
【學位授予單位】：北京中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R259

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