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雙術(shù)湯對腸系膜淋巴結(jié)炎患兒臨床療效的觀察

發(fā)布時(shí)間:2018-06-15 22:48

  本文選題:雙術(shù)湯 + 腸系膜淋巴結(jié)炎; 參考:《廣西中醫(yī)藥大學(xué)》2017年碩士論文


【摘要】:目的:對雙術(shù)湯治療小兒腸系膜淋巴結(jié)炎的臨床療效進(jìn)行客觀評價(jià),為中醫(yī)藥治療該病提供新思路新方法。方法:根據(jù)納入標(biāo)準(zhǔn)選擇符合的腸系膜淋巴結(jié)炎患兒60例,依據(jù)中醫(yī)辨證分型:腹部中寒證,乳食積滯證,胃腸結(jié)熱證,脾胃虛寒證,氣滯血瘀證治療。用雙術(shù)湯辨證加減治療,服藥2個(gè)療程,每個(gè)療程30天。應(yīng)用自身前后對照比較分析,觀察臨床療效,通過比較治療前后五種中醫(yī)證型的中醫(yī)證候積分,五種中醫(yī)證型的中醫(yī)證候療效,腹部彩超提示的腸系膜淋巴結(jié)的數(shù)目和縱橫徑的變化,比較治療前后的主要癥狀體征和次要癥狀,治療前后腹部疼痛緩解情況,腹部壓痛緩解情況及消失率的對比,對臨床療效進(jìn)行評價(jià)。結(jié)果:1.治療前后五種中醫(yī)證型的中醫(yī)證候積分比較,治療后的積分都比治療前顯著下降,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。2.五種中醫(yī)證型的中醫(yī)證候療效比較,差異不具有統(tǒng)計(jì)學(xué)意義(P0.05)。3.復(fù)查腹部彩超顯示腫大的腸系膜淋巴結(jié)數(shù)目與治療前相比減少;縱、橫徑與治療前比較較前縮小,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。4.腹痛及壓痛與治療前相比,治療后患兒腹痛明顯減輕,總有效率為96.67%;腹部壓痛與治療前相比,顯著減輕,總有效率為98.33%,腹痛及腹部壓痛復(fù)發(fā)率低。通過自身前后對照比較,結(jié)果顯示雙術(shù)湯能有效地減輕和消除小兒腸系膜淋巴結(jié)炎引起的腹痛,腹脹,食欲不振,噯氣,嘔吐等癥。治療期間,未見患兒出現(xiàn)汗出過多、惡心等不良反應(yīng),說明雙術(shù)湯治療小兒腸系膜淋巴結(jié)炎安全性較好。結(jié)論:1.雙術(shù)湯能很好地用于不同中醫(yī)證型的腸系膜淋巴結(jié)炎且臨床療效顯著,能很好地改善患兒的臨床癥狀。2.治療后復(fù)查腹部腸系膜淋巴結(jié)彩超,與治療前相比,腫大的腸系膜淋巴結(jié)數(shù)目減少,縱橫徑縮小。3.服藥期間,未見不良反應(yīng),雙術(shù)湯治療本病無毒副作用,用藥安全,值得臨床應(yīng)用和推廣。
[Abstract]:Objective: to evaluate the clinical efficacy of Shuangzhu decoction in the treatment of mesenteric lymphadenitis in children. Methods: according to the inclusive criteria, 60 cases of mesenteric lymphadenitis were selected. According to the differentiation of TCM syndromes: abdominal cold syndrome, milk and food accumulation stagnation syndrome, gastrointestinal knot heat syndrome, spleen and stomach deficiency cold syndrome, qi stagnation and blood stasis syndrome were treated. Add and subtract treatment with Shuangzhu decoction, take medicine for 2 courses, 30 days for each course. The clinical curative effect was observed by comparing and analyzing before and after the treatment. By comparing the TCM syndromes integral of five TCM syndromes before and after treatment, the TCM syndromes of five TCM syndromes were compared and the curative effects of TCM syndromes of five TCM syndrome types were compared. The changes of the number and transverse diameter of mesenteric lymph nodes, the main symptoms, signs and secondary symptoms before and after treatment, the relief of abdominal pain, the relief of abdominal tenderness and the rate of disappearance of abdominal tenderness were compared before and after treatment. To evaluate the clinical effect. The result is 1: 1. The scores of five TCM syndromes before and after treatment were significantly lower than those before and after treatment, and the difference was statistically significant (P 0.05). 2. There was no significant difference in the curative effect of five TCM syndromes. The number of enlarged mesenteric lymph nodes was lower than that before treatment, and the longitudinal and transverse diameter was smaller than that before treatment, and the difference was statistically significant (P 0.05). The abdominal pain and tenderness were significantly alleviated after treatment, the total effective rate was 96.67, and the abdominal tenderness was significantly alleviated, the total effective rate was 98.33, and the recurrence rate of abdominal pain and tenderness was lower. The results showed that Shuangzhu decoction could effectively relieve abdominal pain, abdominal distension, anorexia, belching and vomiting caused by mesenteric lymphadenitis in children. During the treatment, there were no adverse reactions such as excessive sweating and nausea in children, which indicated that Shuangzhoutang was safe in treating mesenteric lymphadenitis in children. Conclusion 1. Shuangzhu decoction can be used in different TCM syndromes of mesenteric lymphadenitis with remarkable clinical efficacy and can improve the clinical symptoms of children. 2. After treatment, the number of enlarged mesenteric lymph nodes was reduced and the transverse and longitudinal diameters were decreased. During the period of taking medicine, there was no adverse reaction. Shuangzhu decoction has no side effects and is safe to use, so it is worthy of clinical application and popularization.
【學(xué)位授予單位】:廣西中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R272

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