本文選題：冠心病 + 阿司匹林抵抗�。� 參考：《中華中醫(yī)藥學刊》2017年05期

【摘要】：目的:探討丹紅注射液對冠心病合并阿司匹林抵抗患者阿司匹林反應單位(aspirin reaction units,ARU)和臨床預后的影響。方法:自2012年1月—2014年1月,前瞻性收集冠心病合并阿司匹林抵抗患者100例,將患者隨機分為研究組(n=50)和對照組(n=50)。研究組在常規(guī)治療的基礎上,聯(lián)合使用丹紅注射液治療;對照組僅采用常規(guī)治療。主要觀察指標為兩組患者ARU和臨床預后。結(jié)果:兩組患者入院時ARU和血小板聚集率差異無統(tǒng)計學意義(P0.05)。與對照組比較,治療后研究組ARU水平顯著降低(540.39±54.39 vs.654.49±39.48,P=00);血小板聚集率顯著降低[(49.59±9.48)%vs.(64.39±8.89)%,P=00)];再次入院率顯著降低(20%vs.40%,P=29)。死亡率、非致死性心梗、卒中和出血發(fā)生率等均無統(tǒng)計學意義(P0.05)。結(jié)論:丹紅注射液有助于降低阿司匹林抵抗患者ARU,降低再入院率。
[Abstract]:Objective: To investigate the effect of Danhong Injection on aspirin reaction units (ARU) and clinical prognosis in patients with coronary heart disease and aspirin resistance. Methods: from January 2012 to January 2014, 100 patients with coronary heart disease combined with aspirin resistance were prospectively collected, and the patients were randomly divided into study group (n=50) and control group (n=50). The study group was treated with Danhong Injection on the basis of routine treatment. The control group was only treated with routine treatment. The main observation index was two groups of patients with ARU and clinical prognosis. Results: there was no significant difference in the ARU and platelet aggregation rate in the two groups (P0.05). Compared with the group, the level of ARU in the study group was significantly lower (54). 0.39 + 54.39 vs.654.49 + 39.48, P=00), platelet aggregation rate decreased significantly [(49.59 + 9.48)%vs. (64.39 + 8.89)%, P=00)], and the readmission rate was significantly decreased (20%vs.40%, P=29). Mortality, non lethal myocardial infarction, stroke and bleeding incidence were not statistically significant (P0.05). Conclusion: Danhong injection helps to reduce ARU in aspirin resistance patients. Reduce reentry rate.
【作者單位】： 寧波市第一醫(yī)院心血管內(nèi)科;寧波市中醫(yī)院心血管內(nèi)科;
【基金】：浙江省中醫(yī)藥科學研究基金計劃項目(2010ZB127)
【分類號】：R259

【相似文獻】

相關(guān)期刊論文 前1條

1 張瑞德;蔡奎;那杰;馬曉玲;劉淑珍;王歡;滕國璽;;中腦導水管周圍灰質(zhì)對貓丘腦后核內(nèi)臟大神經(jīng)誘發(fā)放電的影響[J];針刺研究;1989年Z1期

，

本文編號：2008180