本文選題：健脾滲濕止血方 + 中醫(yī)聯(lián)合療法��； 參考：《河北醫(yī)科大學(xué)》2016年碩士論文

【摘要】：據(jù)資料顯示,目前市場(chǎng)上治療潰瘍性結(jié)腸炎(UC)的灌腸制劑較少,特別是純中藥的制劑更少,西藥多以抗生素加激素等灌腸,效果不確切,與中藥相比副作用較大,遠(yuǎn)期效果不確定。本研究采用“健脾滲濕止血方”(木香10g、訶子10g、茯苓10g、白術(shù)10g、白芍10g、甘草6g、山藥20g、當(dāng)歸10g、仙鶴草30g、薏苡仁30g、馬齒莧30g、槐角10g、地榆炭15g、延胡索10g、白頭翁30g、檳榔12g、升麻6g)口服、保留灌腸及耳穴貼壓對(duì)UC進(jìn)行治療,旨在觀察中醫(yī)聯(lián)合療法治療中度潰瘍性結(jié)腸炎的臨床療效。目的:對(duì)“健脾滲濕止血方”口服、保留灌腸及耳穴貼壓治療中度潰瘍性結(jié)腸炎的臨床療效進(jìn)行評(píng)估。方法:依據(jù)就診順序,按照隨機(jī)數(shù)字表納入40例患者,隨機(jī)單盲,分為治療組和對(duì)照組。治療組予以“健脾滲濕止血方”口服、保留灌腸及耳穴貼壓進(jìn)行治療,對(duì)照組服用常規(guī)美沙拉嗪片加甲硝唑葡萄糖和慶大霉素進(jìn)行治療。觀察記錄治療前后兩組患者的臨床癥狀、體征、中醫(yī)癥候及安全性指標(biāo)。結(jié)果:研究結(jié)果表明治療組和對(duì)照組患者的活動(dòng)性評(píng)分、中醫(yī)癥候療效和臨床療效等觀察指標(biāo)在治療后均得到顯著改善,表明“健脾滲濕止血方”口服、保留灌腸及耳穴貼壓中醫(yī)聯(lián)合療法和傳統(tǒng)的美沙拉嗪療法均對(duì)潰瘍性結(jié)腸炎有一定的療效。1.比較治療3個(gè)月的觀察指標(biāo),結(jié)果表明治療組患者的活動(dòng)性評(píng)分、中醫(yī)癥候療效和臨床療效與對(duì)照組均無明顯差異,說明兩組治療方案的短期治療效果無統(tǒng)計(jì)學(xué)差異。2.對(duì)比治療6個(gè)月后的觀察指標(biāo),結(jié)果表明治療組患者的活動(dòng)性評(píng)分、中醫(yī)癥候療效和臨床療效均明顯優(yōu)于對(duì)照組。結(jié)論:“健脾滲濕止血方”口服、保留灌腸及耳穴貼壓中醫(yī)聯(lián)合療法對(duì)治療中度潰瘍性結(jié)腸炎具有良好的臨床療效,具有推廣價(jià)值。
[Abstract]:According to the data, there are fewer enema preparations for the treatment of ulcerative colitis on the market at present, especially the preparation of pure Chinese medicine, and the western medicine is mostly enema with antibiotics and hormones, the effect is not exact, and the side effect is greater than that of traditional Chinese medicine. The long-term effect is uncertain. In this study, "invigorating spleen and oozing dampness and hemostatic prescription" (10 g of wood incense, 10g of chebula, 10g of Poria cocos, 10g of Atractylodes macrocephala, 10g of Paeoniae Alba, 6g of licorice, 20g of yam, 10g of Angelica sinensis, 30g of purslane, 10g of locust angle, 15g of elm charcoal, 10g of Yanhusuo, 30g of Weng Weng, 12g of betel nut, 6g of Shengma) were taken orally. Retention enema and auricular plaster were used to treat UC in order to observe the clinical effect of TCM combined therapy on moderate ulcerative colitis. Objective: to evaluate the clinical effect of "Jianpi Yizhi Zhixue recipe" in treating moderate ulcerative colitis by oral administration, retention enema and ear point plaster. Methods: according to the order of visit, 40 patients were randomly divided into treatment group and control group. The treatment group was treated by oral administration of "Jianpi Yizhi Zhixue recipe", retention enema and auricular point pressing, while the control group was treated with Metronidazole, glucose and gentamicin. The clinical symptoms, signs, TCM symptoms and safety indexes of the two groups were recorded before and after treatment. Results: the results showed that the activity score, the curative effect of traditional Chinese medicine and the clinical curative effect of the patients in the treatment group and the control group were significantly improved after the treatment, indicating that "Jianpi Yizhi Zhixue prescription" was taken orally. Both retention enema and auricular plaster therapy combined with traditional meralazine therapy have a certain curative effect on ulcerative colitis. 1. The results showed that there was no significant difference in activity score, TCM symptom efficacy and clinical efficacy between the two groups and the control group, indicating that there was no significant difference in short-term therapeutic effect between the two groups. 2. The results showed that the activity score, the curative effect of TCM symptom and the clinical effect of the treatment group were better than those of the control group. Conclusion: the traditional Chinese medicine combination therapy of "invigorating spleen and oozing dampness and stopping bleeding", retention enema and ear point plaster has good clinical effect on treating moderate ulcerative colitis, and it is worth popularizing.
【學(xué)位授予單位】：河北醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

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