本文選題：慢性乙型肝炎 + 脂肪肝�。� 參考：《遼寧中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:通過(guò)對(duì)肝臟內(nèi)部不同病變患者及健康志愿者,肝區(qū)期門(mén)穴彩色多普勒超聲定點(diǎn)檢測(cè)的穴下解剖組織結(jié)構(gòu)的差異性比較研究,從解剖組織形態(tài)學(xué)角度探索肝區(qū)內(nèi)期門(mén)穴反映肝臟病理變化的生物醫(yī)學(xué)基礎(chǔ)。為論證肝募期門(mén)反映病癥效應(yīng)及其相關(guān)的特定穴理論的科學(xué)性提供科學(xué)依據(jù)。材料與方法:對(duì)象及分組:收集病變部位在肝臟的慢乙肝、肝硬化、脂肪肝患者病例114例,健康志愿者資料45例。疾病組采用分層分組的方法,分為慢乙肝組、肝硬化組和脂肪肝組。指標(biāo)檢測(cè)及方法:采用低頻彩色超聲定點(diǎn)垂直超聲檢測(cè)方法,檢測(cè)在肝區(qū)的期門(mén)穴下解剖組織結(jié)構(gòu),以彩超視野中點(diǎn)為原點(diǎn),記錄距離原點(diǎn)最近的肝內(nèi)組織形態(tài)結(jié)構(gòu),總結(jié)并匯總數(shù)據(jù)。分別進(jìn)行肝臟不同疾病狀態(tài)受試者,解剖組織結(jié)構(gòu)檢出率的組間配對(duì)檢驗(yàn),以健康對(duì)照組為基準(zhǔn),探討期門(mén)穴定點(diǎn)超聲所揭示的HBV感染不同病理階段、脂肪肝的肝臟內(nèi)部組織形態(tài)學(xué)的病理變化規(guī)律及特征。使用統(tǒng)計(jì)學(xué)分析軟件SPSS17.0對(duì)采集的數(shù)據(jù)進(jìn)行分析,均值用(?x±s)表示,如檢驗(yàn)結(jié)果P0.05說(shuō)明具有統(tǒng)計(jì)學(xué)意義。結(jié)果:1.健康組與肝內(nèi)病變組配對(duì)檢驗(yàn)結(jié)果(1)慢乙肝、肝硬化肝組織檢出率低于健康組,門(mén)靜脈血管檢出率高于健康組,P0.05(2)脂肪肝矢狀部檢出率高于健康組,P0.05;2.肝內(nèi)病變組間配對(duì)檢驗(yàn)結(jié)果(1)慢乙肝門(mén)靜脈檢出率高于肝硬化、脂肪肝,P0.05,(2)慢乙肝、肝硬化肝組織檢出率小于脂肪肝,P0.05,結(jié)論:1.期門(mén)穴對(duì)應(yīng)的肝臟內(nèi)部解剖組織結(jié)構(gòu)的差異性是影響期門(mén)穴反映病癥效應(yīng)特異性的生物醫(yī)學(xué)基礎(chǔ)。2.慢乙肝、肝硬化不同病理階段門(mén)靜脈干支、矢狀部檢出率增高,符合HBV感染之后,會(huì)出現(xiàn)肝組織纖維化導(dǎo)致門(mén)靜脈高壓,以及有肝臟體積變小的病理演變規(guī)律。體現(xiàn)了“肝以血為用”中醫(yī)理論的科學(xué)性。
[Abstract]:Objective: to compare the differences of anatomical tissue structure of subpoints detected by color Doppler ultrasound at portal acupoints in different liver lesions and healthy volunteers. From the angle of anatomical histomorphology, we explored the biomedical basis of portal point in liver region to reflect the pathological changes of liver. It provides a scientific basis for demonstrating the effect of liver disease and its related theory of specific acupoints. Materials and methods: 114 patients with chronic hepatitis B, liver cirrhosis and fatty liver were collected and 45 healthy volunteers were collected. The disease group was divided into chronic hepatitis B group, liver cirrhosis group and fatty liver group. Indexes and methods: low frequency color ultrasound was used to detect the anatomical structure of liver tissue under the point of stage gate. The middle point of the field of vision of color Doppler ultrasound was used as the origin to record the structure of the liver tissue nearest to the origin. Summarize and summarize data. The detection rate of anatomical tissue structure of different liver diseases in subjects was tested by paired group, and the pathological stages of HBV infection revealed by sentinel ultrasound at portal acupoint were studied by using the healthy control group as the reference. Pathological changes and characteristics of liver histomorphology in fatty liver. The statistical analysis software SPSS 17.0 was used to analyze the collected data, the mean value was expressed by X 鹵s, such as the test results P0.05 showed statistical significance. The result is 1: 1. 1) the detection rate of chronic hepatitis B and liver cirrhosis in liver tissue was lower than that in healthy group, and the detection rate of portal vein was higher than that in healthy group (P0.05 / 2) the sagittal detection rate of fatty liver was higher than that in healthy group. The detection rate of chronic hepatitis B in portal vein was higher than that in liver cirrhosis, and that in fatty liver tissue was lower than that in fatty liver tissue. The difference of the anatomical structure of the liver corresponding to the point gate is the biomedical basis that affects the specificity of the disease effect at the point gate. The detection rate of portal vein dry branch in different pathological stages of chronic hepatitis B and liver cirrhosis was higher than that in sagittal part, which was consistent with the pathological evolution of hepatic fibrosis and portal hypertension after HBV infection. It reflects the scientific nature of traditional Chinese medicine theory of "liver is used by blood".
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R246.1

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本文編號(hào)：2003923