本文選題：慢性腎衰竭 + 高磷血癥　； 參考：《成都中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：本研究旨在探索慢性腎衰竭合并高磷血癥的非透析患者的中醫(yī)證候分布情況,并研究其中醫(yī)證型與實驗室指標(biāo)有無相關(guān)性,為慢性腎衰竭合并高磷血癥的非透析患者提供客觀中醫(yī)辨證依據(jù)。方法：本研究以慢性腎衰竭合并高磷血癥的非透析患者為研究對象,采用橫斷面調(diào)查的試驗設(shè)計,收集132例患者一般情況,按照中醫(yī)證候標(biāo)準(zhǔn)分為不同證型,同時收集血肌酐、血鈣、血磷、估算腎小球濾過率、血紅蛋白、血清白蛋白、促甲狀旁腺激素等實驗室檢查結(jié)果,對慢性腎衰竭中醫(yī)證型分布情況及中醫(yī)證型與以上實驗室結(jié)果的相關(guān)性進(jìn)行統(tǒng)計學(xué)分析。結(jié)果：1.慢性腎衰竭合并高磷血癥非透析患者中醫(yī)證候分布以本虛證為主,本虛諸證中氣虛證最多,占52.27%,其次是陰虛證、陽虛證,血虛證較少見；標(biāo)實兼證以水濕證多見,占33.33%,其次是血瘀證、濕熱證,溺毒證較少見,部分無兼證。2.隨著腎功能的下降,慢性腎衰竭合并高磷血癥非透析患者血磷水平呈升高趨勢,當(dāng)CKD達(dá)到4期后血磷水平出現(xiàn)明顯升高。3.慢性腎衰竭合并高磷血癥非透析患者不同本虛證型之間,血磷水平血虛證陰虛證陽虛證氣虛證,但差異無統(tǒng)計學(xué)意義。4.慢性腎衰竭合并高磷血癥非透析患者中血虛證的血肌酐、估算腎小球濾過率、血紅蛋白、血鈣都與其他證型有統(tǒng)計學(xué)差異,因此在臨床辨證可將以上指標(biāo)作為血虛證的參考指標(biāo)。結(jié)論：慢性腎衰竭合并高磷血癥非透析患者本虛諸證中氣虛證最多見。慢性腎衰竭合并高磷血癥非透析患者血虛證與血肌酐、估算腎小球濾過率、血紅蛋白、血鈣、甲狀旁腺激素、血清白蛋白等實驗室指標(biāo)之間存在一定的相關(guān)性。
[Abstract]:Objective: to explore the distribution of TCM syndromes in non-dialysis patients with chronic renal failure and hyperphosphatemia, and to study the correlation between TCM syndromes and laboratory indexes. To provide objective TCM syndrome differentiation basis for non-dialysis patients with chronic renal failure and hyperphosphatemia. Methods: in this study, 132 patients with chronic renal failure complicated with hyperphosphatemia were divided into different syndromes, and blood creatinine was collected according to TCM syndrome standard, using a cross-sectional investigation of the experimental design, 132 patients were divided into different syndromes according to the criteria of TCM syndromes, and blood creatinine was collected at the same time. Blood calcium, blood phosphorus, estimated glomerular filtration rate, hemoglobin, serum albumin, parathyroid hormone and other laboratory results, The distribution of TCM syndromes of chronic renal failure (CRF) and the correlation between TCM syndromes and the above laboratory results were analyzed statistically. The result is 1: 1. In patients with chronic renal failure and hyperphosphatemia, the distribution of TCM syndromes was mainly based on the syndrome of deficiency of essence, the most of which was deficiency of qi (52.27), followed by deficiency of yin, deficiency of yang, and deficiency of blood. Accounted for 33. 33, followed by blood stasis syndrome, damp-heat syndrome, drug addiction syndrome is rare, some without a concurrent syndrome. 2. With the decline of renal function, the level of blood phosphorus in patients with chronic renal failure and hyperphosphatemia showed an increasing trend. When CKD reached 4 stages, the level of serum phosphorus increased significantly. 3. Chronic renal failure combined with hyperphosphatemia non-dialysis patients with different types of deficiency of blood phosphorus level of blood deficiency of yin and yang deficiency of qi syndrome, but the difference is not statistically significant. 4. The blood creatinine, glomerular filtration rate, hemoglobin and serum calcium in patients with chronic renal failure and hyperphosphatemia were significantly different from those of other syndrome types. Therefore, in clinical syndrome differentiation, the above indexes can be taken as the reference index of blood deficiency syndrome. Conclusion: deficiency of Qi syndrome is most common in patients with chronic renal failure and hyperphosphatemia. There was a certain correlation between blood deficiency and serum creatinine in patients with chronic renal failure and hyperphosphatemia, estimating glomerular filtration rate, hemoglobin, serum calcium, parathyroid hormone, serum albumin and other laboratory indexes.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R277.5

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