發(fā)布時(shí)間：2018-06-03 12:32

  本文選題：腹部推拿 + 心脾兩虛型廣泛性焦慮癥�。� 參考：《遼寧中醫(yī)雜志》2017年12期

【摘要】：目的:評(píng)價(jià)腹部推拿治療心脾兩虛型廣泛性焦慮癥的臨床療效。方法:將符合心脾兩虛型廣泛性焦慮癥納入標(biāo)準(zhǔn)的60例患者,按隨機(jī)數(shù)字表法分為試驗(yàn)組和對(duì)照組各30例。試驗(yàn)組給予腹部推拿治療,每日治療1次,每次40min;對(duì)照組給予口服丁螺環(huán)酮5 mg,每日3次;兩組均15 d為1個(gè)療程,治療2個(gè)療程。分別對(duì)兩組患者治療前后血漿五羥色胺(5-HT)含量及臨床癥狀進(jìn)行比較,并對(duì)患者的治療前、治療后及隨訪時(shí)(療程結(jié)束后3個(gè)月)的焦慮自評(píng)量表(SAS)和漢密爾頓焦慮量表(HAMA)評(píng)分進(jìn)行比較和評(píng)價(jià)。結(jié)果:試驗(yàn)組總有效率92.59%,愈顯率55.56%;對(duì)照組總有效率86.96%,愈顯率52.2%,兩組比較無顯著性差異(P0.05)。兩組療法對(duì)于改善緊張不安、失眠健忘兩種癥狀的臨床療效無顯著性差異(P0.05),而對(duì)于改善腹脹便溏癥狀方面,試驗(yàn)組則明顯優(yōu)于對(duì)照組(P0.05)。兩組患者治療30 d后,5-HT含量、SAS評(píng)分以及HAMA評(píng)分均較治療前顯著下降(P0.05),且兩組間比較無明顯差異(P0.05)。治療后3個(gè)月隨訪結(jié)果顯示,試驗(yàn)組SAS評(píng)分及HAMA評(píng)分均無明顯上升(P0.05);而對(duì)照組SAS評(píng)分及HAMA評(píng)分較治療前均有明顯反彈(P0.05)。不良反應(yīng)分析方面,試驗(yàn)組患者無不良反應(yīng)出現(xiàn);對(duì)照組4例出現(xiàn)不良反應(yīng),不良反應(yīng)發(fā)生率為13.33%。結(jié)論:腹部推拿可有效治療心脾兩虛型廣泛性焦慮癥,并具有操作簡(jiǎn)便、無創(chuàng)、無不良反應(yīng)、療效穩(wěn)定持久等優(yōu)勢(shì),值得臨床進(jìn)一步研究推廣。
[Abstract]:Objective: to evaluate the clinical effect of abdominal massage on generalized anxiety disorder with deficiency of heart and spleen. Methods: 60 patients with generalized anxiety disorder with deficiency of heart and spleen were divided into two groups according to random digital table: the experimental group (n = 30) and the control group (n = 30). The experimental group was treated with abdominal massage once a day for 40 minutes, while the control group was given oral bupirone 5 mg 3 times a day, both 15 days as a course of treatment, 2 courses of treatment. Plasma serotonin 5-HT levels and clinical symptoms were compared between the two groups before and after treatment. The scores of self-rating anxiety scale (SAS) and Hamilton anxiety scale (Hama) were compared and evaluated after treatment and follow-up (3 months after the end of the course of treatment). Results: the total effective rate of the test group was 92.59%, the more obvious rate was 55.56%, the total effective rate of the control group was 86.96%, the more obvious rate was 52.2%, there was no significant difference between the two groups (P 0.05). There was no significant difference in clinical effect between the two groups in improving tension and restlessness, and there was no significant difference in the clinical effect of insomnia and amnesia. However, the experimental group was better than the control group in improving the symptoms of loose stools. After 30 days of treatment, the scores of 5-HT and HAMA in both groups were significantly lower than those before treatment (P 0.05), and there was no significant difference between the two groups (P 0.05). The results of follow-up 3 months after treatment showed that there was no significant increase in SAS score and HAMA score in the trial group, while the SAS score and HAMA score in the control group were significantly higher than those before treatment. There were no adverse reactions in the test group and 4 cases in the control group, with an adverse reaction rate of 13.33%. Conclusion: abdominal massage can effectively treat generalized anxiety disorder with deficiency of heart and spleen, and has the advantages of simple operation, non-invasive, no adverse reaction, stable and lasting curative effect and so on, which is worthy of further clinical study and promotion.
【作者單位】： 天津中醫(yī)藥大學(xué)第一附屬醫(yī)院;
【基金】：國(guó)家自然科學(xué)基金項(xiàng)目(81473793)
【分類號(hào)】：R277.7

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