本文選題：慢性萎縮性胃炎 + 健脾疏肝清熱化瘀法　； 參考：《南京中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:觀察健脾疏肝清熱化瘀法治療慢性萎縮性胃炎(Chronic atrophic gastritis,CAG)脾虛肝郁夾瘀證的臨床療效,探討健脾疏肝清熱化瘀法治療CAG的臨床價值。方法:將符合西醫(yī)和中醫(yī)納入標(biāo)準(zhǔn)的60例CAG患者,隨機(jī)分為對照組和治療組,每組30例,治療組口服健脾疏肝清熱化瘀方,對照組僅服用胃復(fù)春片,共治療6個月,觀察記錄兩組在治療前后主要癥狀、次要癥狀、內(nèi)鏡病理變化,療程結(jié)束后匯總、評估療效、分析結(jié)果。結(jié)果:兩組患者運用不同治療方案后將其綜合療效對比,治療組30例中,治愈5例,顯效9例,有效12例,無效4例,總有效率86.67%;對照組30例中,治愈2例,顯效6例,有效9例,無效13例,總有效率56.67%。兩組綜合療效分析,治療組的臨床療效優(yōu)于對照組(P0.05)。兩組單個臨床癥狀積分對比,在胃脘疼痛、口苦口干、食少納差方面,治療組的臨床療效優(yōu)于對照組(P0.05),對于胃胺及(或)脅肋部痞脹、嘈雜、心煩易怒、倦怠乏力、大便稀溏癥狀,兩組治療效果明顯,同時兩組療效相當(dāng)(P0.05)。病理療效比較,兩組均有好轉(zhuǎn),在治療粘膜萎縮方面,治療組療效優(yōu)于對照組(P0.05),在治療腸化、異型增生方面,兩組療效相當(dāng)(P0.05)。療程中,所有患者均未出現(xiàn)不良反應(yīng)。結(jié)論:健脾疏肝清熱化瘀法治療CAG效果明確,可顯著改善患者不適癥狀,提高患者生活質(zhì)量;同時可有效阻止CAG的進(jìn)展,使萎縮的腺體恢復(fù)正常或者減輕其萎縮的程度。
[Abstract]:Objective: to observe the clinical effect of invigorating spleen and soothing liver and clearing away heat and removing blood stasis in treating chronic atrophic gastritis with chronic atrophic gastritis (chronic atrophic gastritis) and to explore the clinical value of strengthening spleen and soothing liver and clearing away heat and removing blood stasis in treating CAG. Methods: sixty patients with CAG were randomly divided into control group and treatment group, 30 cases in each group. The treatment group was treated with Jianpi Shugan Qiehuayu decoction, while the control group was treated with Weifuchun tablet for 6 months. The main symptoms secondary symptoms endoscopy pathological changes were observed and recorded before and after treatment the curative effect was evaluated and the results were analyzed. Results: the comprehensive curative effects of the two groups were compared after using different treatment schemes. In the treatment group, 5 cases were cured, 9 cases were markedly effective, 12 cases were effective, 4 cases were ineffective, and the total effective rate was 86.67%, while in the control group, 2 cases were cured, 6 cases marked effect. The total effective rate was 56.67. The clinical efficacy of the treatment group was better than that of the control group (P 0.05). The clinical effect of the treatment group was better than that of the control group in terms of epigastric pain, dry mouth, and poor appetite. The clinical efficacy of the treatment group was better than that of the control group (P 0.05). For stomach amine and / or hypochondrial distension, noise, irritability, tiredness and fatigue, the treatment group was more effective than the control group. The symptoms of loose stool were obvious in the two groups, and the curative effect of the two groups was similar to that of P0.05. In the treatment of mucosal atrophy, the therapeutic effect of the treatment group was better than that of the control group (P 0.05), and the curative effect of the two groups in the treatment of intestinal metaplasia and dysplasia was similar to that in the treatment of intestinal metaplasia and dysplasia. During the course of treatment, no adverse reactions were found in all patients. Conclusion: the method of invigorating spleen, soothing liver and clearing away heat and removing blood stasis is effective in the treatment of CAG, which can significantly improve the symptoms of discomfort and improve the quality of life of the patients, at the same time, it can effectively prevent the progress of CAG, restore the atrophic glands to normal or reduce the degree of atrophy.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259

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