本文選題：慢性尿路感染 + 無(wú)比山藥丸加減方��； 參考：《山東中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:觀察無(wú)比山藥丸加減方治療慢性尿路感染脾腎虧虛,濕濁潴留證的臨床療效,評(píng)價(jià)無(wú)比山藥丸加減方治療慢性尿路感染的臨床效果以及安全性,為豐富中醫(yī)藥治療慢性尿路感染提供新的思路、減少抗生素的使用提供理論依據(jù)。方法:將符合納入標(biāo)準(zhǔn)的60例患者,隨機(jī)分為試驗(yàn)組30例,對(duì)照組30例。對(duì)照組予基礎(chǔ)治療加用復(fù)方石韋膠囊治療,試驗(yàn)組在基礎(chǔ)治療的基礎(chǔ)上予無(wú)比山藥丸加減方中藥煎劑。兩組均治療4周。觀察患者治療前后尿白細(xì)胞(WBC)、中段尿細(xì)菌培養(yǎng)及中醫(yī)癥狀和證候積分的變化。所有數(shù)據(jù)處理均在SPSS17.0統(tǒng)計(jì)軟件上進(jìn)行,P0.05為有顯著差異;P0.01為有非常顯著差異;P0.05為無(wú)顯著差異。結(jié)果:(1)中醫(yī)證候療效:試驗(yàn)組治愈率3.33%、顯效率56.67%、有效率40.00%、總有效率100%,對(duì)照組顯效率3.33%、有效率83.33%、無(wú)效率13.33%、總有效率86.67%。試驗(yàn)組用藥前后癥狀積分相比具有非常顯著的統(tǒng)計(jì)學(xué)差異(p0.01)。(2)理化指標(biāo):與對(duì)照組相比,試驗(yàn)組治療后中醫(yī)量化評(píng)分明顯優(yōu)于對(duì)照組(p0.01)、尿白細(xì)胞療效效果優(yōu)于對(duì)照組(p0.05)、中段尿細(xì)菌培養(yǎng)療效效果優(yōu)于對(duì)照組(p0.05)。(3)安全性:試驗(yàn)組治療前后肝腎功能無(wú)顯著改變(p0.05)且均在正常范圍,臨床應(yīng)用安全,無(wú)明顯副作用。結(jié)論:無(wú)比山藥丸加減方治療慢性尿路感染(勞淋)脾腎虧虛,濕濁潴留證,能顯著改善患者尿頻、尿急、遇勞即發(fā)、神疲乏力、腰膝酸軟、頭暈耳鳴等脾腎虧虛,濕濁潴留證的中醫(yī)證候表現(xiàn),能顯著改善尿菌及臨床癥狀,從而顯示出無(wú)比山藥丸加減方治療本病的優(yōu)勢(shì)。
[Abstract]:Objective: to observe the clinical effect of Heishan pills plus and subtractive prescription in the treatment of chronic urinary tract infection with deficiency of spleen and kidney and retention of dampness, and to evaluate the clinical effect and safety of the treatment of chronic urinary tract infection. To enrich the treatment of chronic urinary tract infection with Chinese medicine to provide new ideas, reduce the use of antibiotics to provide a theoretical basis. Methods: 60 patients were randomly divided into trial group (n = 30) and control group (n = 30). The control group was treated with basic therapy plus compound Shiwei capsule, and the experimental group was treated with the decoction of Chinese medicine of the addition and subtractive prescription of Cengshan pills on the basis of basic treatment. Both groups were treated for 4 weeks. Before and after treatment, the changes of WBCU, bacterial culture in middle urine and TCM symptoms and syndromes were observed. All the data were processed on SPSS17.0 statistical software for significant difference (P0.05). P0.01 was very significant difference (P0.05) was no significant difference. Results: the curative effect of TCM syndromes: the cure rate of the experimental group was 3.33, the effective rate was 56.67, the effective rate was 40.00, the total effective rate was 100, the control group was 3.33, the effective rate was 83.33, the inefficiency was 13.33and the total effective rate was 86.67. There was a significant statistical difference in symptom scores before and after treatment in the trial group (P 0.01. 0. 2) physical and chemical indexes: compared with the control group, After treatment, the quantitative score of TCM in the experimental group was significantly better than that in the control group (p0.01g), the effect of urinary leukocyte was better than that of the control group (p0.05), and the effect of bacterial culture in the middle segment of urine was better than that of the control group (p0.05.) the safety of the experimental group was not significantly improved before and after treatment. And all in the normal range. The clinical application is safe and has no obvious side effects. Conclusion: the treatment of deficiency of spleen and kidney, retention of dampness and turbidity in patients with chronic urinary tract infection (Laolin) by adding and reducing prescription of Dingshan pills can significantly improve the frequency of urine, urination urgency, imminent fatigue, weakness of waist and knee, dizziness, tinnitus and other deficiency of spleen and kidney. The TCM syndromes of dampness retention syndrome can significantly improve the urine bacteria and clinical symptoms, thus showing the advantages of Heishanshan pills plus and minus prescription in the treatment of this disease.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：R277.5

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