本文選題：失眠 + 馬來西亞��； 參考：《福建中醫(yī)藥大學(xué)》2016年博士論文

【摘要】：目的：通過溫膽湯加味治療馬來西亞地區(qū)痰熱內(nèi)擾型失眠的臨床觀察,評價(jià)其臨床效應(yīng)并探討其臨床機(jī)制,為馬來西亞痰熱內(nèi)擾型失眠的治療提供安全、有效的方法。方法：選擇2015年4月至2016年3月在馬來西亞霹靂怡保仁愛醫(yī)院與霹靂金寶德安堂藥行門診就診,符合課題納入、排除標(biāo)準(zhǔn)的120例痰熱內(nèi)擾型失眠患者為研究對象,予溫膽湯加味科學(xué)濃縮中藥顆粒劑,連續(xù)治療4周,治療后觀察患者的臨床療效,比較治療前后中醫(yī)證候?qū)W積分、匹茲堡睡眠質(zhì)量指數(shù)量表(PSQI)積分的差異性,評價(jià)調(diào)膽和胃,清熱化痰,健脾安神法對失眠病人的治療作用。結(jié)果：本次研究共搜集120例符合納入、排除標(biāo)準(zhǔn)的病例,其中男性28例,占23.3%,女性92例,占76.6%,平均年齡45.75±10.72歲。治療后痊愈8例、顯效62例、有效42例、無效8例,所占比率分別為6.66%、51.66%、35%及6.66%,總有效率達(dá)93.3%。匹茲堡睡眠質(zhì)量指數(shù)量表(PSQI)積分比較：治療前積分17.40±2.509,治療后積分5.17±3.206,治療前后PSQI分?jǐn)?shù)采用配對Z檢驗(yàn),有統(tǒng)計(jì)學(xué)意義(P0.05),即治療后較治療前PSQI評分降低。中醫(yī)癥候?qū)W積分比較：治療前積分23.63±3.970,治療后積分6.50±4.605,治療前后采用配對Z檢驗(yàn),有統(tǒng)計(jì)學(xué)意義(P0.05),即治療后較治療前中醫(yī)癥候?qū)W評分降低。結(jié)論：通過本研究得出,溫膽湯加味治療馬來西亞地區(qū)痰熱內(nèi)擾型失眠癥狀明顯改善,睡眠治療明顯提高,臨床療效顯著�！罢{(diào)膽和胃,清熱化痰,健脾安神”法是治療痰熱內(nèi)擾失眠的有效法則。
[Abstract]:Objective: To evaluate the clinical effects and clinical mechanism of Wendan Decoction in the treatment of phlegm heat internal disturbance in Malaysia area, and to explore its clinical mechanism, and provide a safe and effective method for the treatment of insomnia in Malaysia's phlegm heat internal disturbance. Methods: from April 2015 to March 2016, Ipoh benevolent hospital and thunderbolt in Malaysia were selected. 120 cases of insomnia patients with phlegm heat internal disturbance were taken as the research object, and the clinical curative effect was observed after treatment for 4 weeks, and the TCM syndrome scores before and after treatment were compared with the Pittsburgh sleep quality index scale (PSQI). The difference of the score, evaluate the therapeutic effect of gall and stomach, heat clearing and phlegm, invigorating spleen and Anshen on insomnia patients. Results: 120 cases were collected in this study, including 28 cases of male, 23.3%, 92 women, 76.6% and 45.75 10.72 years old. After treatment, 8 cases were cured, 62 cases were markedly effective, 42 cases effective, 8 cases null and void, The ratio was 6.66%, 51.66%, 35% and 6.66%, and the total effective rate was compared with the 93.3%. Pittsburgh sleep quality index (PSQI) score: 17.40 + 2.509 before treatment and 5.17 + 3.206 after treatment. The PSQI score before and after treatment was statistically significant (P0.05), that is, lower than the pre treatment PSQI score after treatment. Integral comparison: the score was 23.63 + 3.970 before treatment and 6.50 + 4.605 after treatment. The matched Z test before and after treatment had statistical significance (P0.05), that is to say, the score of TCM syndrome was lower than before treatment. Conclusion: through this study, it is concluded that the symptoms of phlegm heat internal disturbance in Malaysia area are obviously improved and sleep treatment is treated by this study. The method of regulating gallbladder and stomach, clearing away heat and resolving phlegm, strengthening spleen and tranquilizing mind are effective rules for treating insomnia caused by phlegm heat.
【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：博士
【學(xué)位授予年份】：2016
【分類號(hào)】：R256.23
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本文編號(hào)：1915857