基于數(shù)據(jù)挖掘的藏醫(yī)藥治療高原紅細胞增多癥方劑組方用藥規(guī)律分析
發(fā)布時間:2018-05-19 21:13
本文選題:藏醫(yī)藥 + HAPC。 參考:《遼寧中醫(yī)雜志》2017年11期
【摘要】:目的:基于數(shù)據(jù)挖掘方法,運用中醫(yī)傳承輔助平臺軟件(V2.5),分析《四部醫(yī)典》等藏醫(yī)藥書籍中治療HAPC方劑的組方用藥規(guī)律,為進一步挖掘藏醫(yī)治療HAPC方案及新藥的研發(fā)提供參考。方法:HAPC屬于藏醫(yī)血隆病的范疇,俗稱"多血癥"。為揭示藏醫(yī)藥治療該病方劑組方用藥規(guī)律,通過整理《四部醫(yī)典》等藏醫(yī)藥書籍中的相關治療方劑,應用中醫(yī)傳承輔助平臺軟件(V2.5),構(gòu)建藏醫(yī)治療HAPC的方劑數(shù)據(jù)庫,采用軟件集成的數(shù)據(jù)挖掘方法,進行頻次統(tǒng)計、組方規(guī)律、關聯(lián)規(guī)則分析、新方分析和證型分布。結(jié)果:收集了治療HAPC的210首方劑,確定了處方中藥物出現(xiàn)的頻次、常用藥對及組合,其中使用頻率最高的10味藥分別是訶子、木香、紅花、余甘子、肉豆蔻、豆蔻、丁香、土木香、天竺黃、毛訶子,累計用藥頻率達33.19%。發(fā)現(xiàn)支持度≥20%,置信度≥0.9的關聯(lián)規(guī)則共演化得出新處方11首。結(jié)論:用藥頻率較高藏藥的藥性均以針對血型HAPC治療為主,依次是隆型、赤巴型、培根型、木布病等5種分型,體現(xiàn)了該病在不同分型下有不同的治療原則和組方用藥規(guī)律,為藏醫(yī)臨床辨證論治和進一步新藥開發(fā)提供了科學意義及數(shù)據(jù)支撐。
[Abstract]:Objective: based on the method of data mining, using the software of traditional Chinese Medicine (TCM) inheriting and assisting platform, the author analyzed the rule of prescription for treating HAPC in four medical books, so as to provide a reference for further excavating the scheme of Tibetan medicine for treating HAPC and the research and development of new drugs. Methods: HAP-PC belongs to the category of blood Carina disease of Tibetan medicine, commonly known as "polyaemia". In order to reveal the prescriptions of Tibetan medicine for treating this disease, the database of Tibetan medicine HAPC was constructed by sorting out the related prescriptions in the Tibetan medicine books, and using the software of Chinese medicine heritage assistant platform (V2.5). The data mining method of software integration is used to carry out frequency statistics, square rule, association rule analysis, new side analysis and pattern distribution. Results: 210 prescriptions for the treatment of HAPC were collected, and the frequency, frequency and combination of the drugs in the prescriptions were determined. Among them, the 10 drugs with the highest frequency of use were Fructus chebula, Amur, Cardamom, cardamom and clove, respectively. Civil incense, Tianzhu yellow, Chexotic, cumulative drug use frequency of 33.19. It is found that the association rules with support 鈮,
本文編號:1911707
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