本文選題：“祛瘀生新”療法 + 帶狀皰疹后神經(jīng)痛��； 參考：《南京中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：評(píng)價(jià)“祛瘀生新”療法對(duì)帶狀皰疹后神經(jīng)痛患者疼痛及生活質(zhì)量的改善情況,探討此療法對(duì)不同疼痛性質(zhì)PHN療效的差異性及時(shí)效性。方法：將符合納入標(biāo)準(zhǔn)的40例PHN患者隨機(jī)分為治療組、對(duì)照組,每組20例,設(shè)立A組為治療組,采用“祛瘀生新”療法；B組為藥物對(duì)照組,采用口服加巴噴丁的治療。治療周期為3周,分別于治療后第1、2、3周后觀察療效。觀察治療前后三組患者視覺(jué)疼痛模擬量表(VAS)、McGill疼痛積分表、阿森斯失眠量表(AIS)的評(píng)定結(jié)果,并根據(jù)評(píng)價(jià)標(biāo)準(zhǔn)對(duì)療效進(jìn)行評(píng)估。結(jié)果：1.兩組總有效率分別是95%和85%,比較具有顯著差異(P0.05),A組優(yōu)于B組。2.兩組患者治療3周后的VAS積分、AIS的比較具有顯著性差異(P0.05),A組優(yōu)于B組。兩組患者治療第1周的VAS評(píng)分下降值比較,P0.05,兩組之間有顯著性差異,A組在治療第一周時(shí)對(duì)疼痛的改善程度優(yōu)于B組。3.兩組患者治療前后McGill計(jì)分比較,P0.01,均有顯著性差異,兩組治療后McGill計(jì)分和兩組治療前后差值比較,P0.05,差異均有統(tǒng)計(jì)學(xué)意義。A組患者刺痛、熱灼痛、觸痛、跳痛、牽扯痛的McGill計(jì)分與B組相比,具有顯著差異(P0.05),其中對(duì)觸痛的改善效果最為明顯。B組患者刀割痛、撕裂痛的McGill計(jì)分與A組相比,具有顯著差異(P0.05)。結(jié)論：1.“祛瘀生新”療法能夠有效改善PHN患者疼痛程度及睡眠質(zhì)量2.“祛瘀生新”療法治療PHN的止痛起效速度明顯優(yōu)于口服加巴噴丁,起效時(shí)間更短；3.“祛瘀生新”療法對(duì)于觸痛、刺痛、熱灼痛、牽扯痛、跳痛的改善程度優(yōu)于口服加巴噴丁,且對(duì)觸痛的改善程度最為顯著,口服加巴噴丁療對(duì)刀割樣痛、撕裂樣痛的改善效果更好。
[Abstract]:Objective: to evaluate the improvement of pain and quality of life in patients with post herpes zoster neuralgia treated with Quyu Shengxin (QXT), and to explore the difference and time effect of this therapy in treating PHN with different pain. Methods: forty patients with PHN were randomly divided into treatment group (n = 20) and control group (n = 20). Group A was set up as treatment group, group B was treated with "Quyu Shengxin" as drug control group, and treated by oral administration of gabapentin. The treatment period was 3 weeks and the curative effect was observed 3 weeks after treatment. The evaluation results of visual pain analogue scale (VASA) McGill's pain score scale (AIS) and AIS scale before and after treatment were observed and the curative effect was evaluated according to the evaluation criteria. The result is 1: 1. The total effective rates of the two groups were 95% and 85%, respectively. There was a significant difference in VAS scores between the two groups after 3 weeks of treatment. Group A was better than group B. There was significant difference between the two groups in the decrease of VAS score in the first week of treatment (P 0.05). The improvement of pain in group A was better than that in group B at the first week of treatment (P 0.05). There was significant difference in McGill score between the two groups before and after treatment (P 0.01). The difference between the two groups in McGill score and the difference between the two groups before and after treatment was significant (P 0.05). The difference was statistically significant in group A. the patients in group A had stinging pain, heat burning pain, tenderness and jumping pain. There was significant difference in McGill score between group B and group B. among them, the effect of improving tenderness was the most obvious. The McGill score of group B was significantly different from that of group A (P 0.05). Conclusion 1. Quyu Shengxin therapy can effectively improve the pain degree and sleep quality of PHN patients. The analgesic effect of "Quyu Shengxin" therapy on PHN was significantly faster than that of oral gabapentin, and the effective time was much shorter than that of gabapentin. The improvement degree of "Quyu Shengxin" therapy for tenderness, stinging, heat burning, pulling pain and jumping pain was better than that of oral gabapentin, and the improvement degree of tenderness was the most obvious. The effect of tearing pain is better.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：R275.9

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