本文選題：輕度認知障礙 + 老年人　； 參考：《福建中醫(yī)藥大學》2017年碩士論文

【摘要】：目的:本文旨在探討福州市輕度認知障礙(mild cognitive impairment,MCI)老年人中醫(yī)證素分布規(guī)律及其與影響因素的關系,為MCI證素特征研究及中醫(yī)藥防治MCI提供理論依據(jù)。方法:采用橫斷面調(diào)查研究設計,收集福州市306名社區(qū)MCI老年人中醫(yī)證候信息及影響因素情況,采用證素辨證法,計算證素頻率和證素診斷輕重程度,利用描述性分析,卡方檢驗,秩和檢驗等方法綜合分析MCI老年人中醫(yī)證素與影響因素的相關性。結果:1.MCI老年人的中醫(yī)證素特征:病位證素主要以肝(150,49.02%)、腎(148,48.37%)為主,其次為心(95,31.05%)、心神(腦)(62,20.26%)、膽(57,18.63%);主要虛性證素為陽虛(177,57.84%)、血虛(170,55.56%)、陰虛(164,53.59%)、氣虛(156,50.98%);主要實性證素為:痰(103,33.66%)、氣滯(100,32.68%)、濕(70,22.88%)、熱(41,13.40%)。2.證素與性別的關系:女性肝、腎、心證素頻率較男性高(P0.05);在心證素診斷輕重程度上,女性在輕度頻率較男性為低,中度、重度頻率為高(P0.05)。3.證素與年齡的關系:70歲及以上MCI老年人在陽虛、血虛、陰虛、氣虛證素的頻率高于60-69歲MCI老年人(P0.05);在陽虛證素診斷輕重程度上,60-69歲MCI老年人在輕度、中度頻率分布較70歲以上MCI老年人高,重度頻率為低(P0.05);在血虛證素診斷輕重程度上,60-69歲MCI老年人在輕度頻率分布較70歲以上MCI老年人高,中度、重度頻率分布為低(P0.05)。4.證素與吸煙的關系:無吸煙習慣的MCI老年人在血虛、氣虛證素頻率上較有吸煙習慣的MCI老年人高(P0.05)。5.證素與飲酒的關系:在肝證素診斷輕重程度上,有飲酒習慣的MCI老年人在輕度的頻率分布較無飲酒習慣的MCI老年人為低,在中度、重度的頻率分布為高(P0.05);在氣虛證素診斷輕重程度上,有飲酒習慣的MCI老年人在輕度頻率分布為高,在中度、重度頻率分布為低(P0.05)。6.證素與家族癡呆病史的關系:不同家族癡呆病史的MCI老年人在中醫(yī)證素頻率與證素診斷輕重程度上差異均無統(tǒng)計學意義(P0.05)。7.證素與高血壓病史的關系:有高血壓病史的MCI老年人在陰虛證素診斷輕重程度分布上較無高血壓病史的MCI老年人在輕度頻率分布上為高,在中度、重度頻率分布上為低(P0.05)。8.證素與有無規(guī)律運動的關系:有規(guī)律運動的MCI老年人腎、心、心神(腦)、陽虛、血虛、氣虛證素頻率較無規(guī)律運動的MCI老年人低(P0.05)。9.證素與職業(yè)勞動方式的關系:以腦力勞動為主的MCI老年人在陽虛證素頻率上較以體力勞動為主的MCI老年人低(P0.05);在膽、氣滯證素診斷輕重程度上,以體力勞動作為職業(yè)勞動方式為主的MCI老年人在中度和重度頻率分布上較以腦力勞動作為職業(yè)勞動方式為主的MCI老年人為高,輕度頻率分布為低(P0.05)。結論:1.MCI老年人病位證素主要在肝、腎、心、心神(腦)、膽;病性證素主要為陽虛、血虛、陰虛、氣虛、痰、氣滯、濕、熱。2.MCI老年人證素特點在一定程度上與性別、年齡、吸煙情況、飲酒情況、高血壓病史、有無規(guī)律運動及職業(yè)勞動方式有關。
[Abstract]:Objective: the purpose of this paper is to explore the distribution of TCM syndrome in mild cognitive impairment (MCI) and its relationship with the influencing factors in Fuzhou, and to provide a theoretical basis for the study of MCI characteristics and the prevention and control of traditional Chinese medicine (MCI). Methods: a cross-sectional study was designed to collect the traditional Chinese medicine of the 306 elderly people in the community of Fuzhou. Syndrome differentiation and syndrome differentiation method were used to calculate the degree of syndrome factor frequency and the degree of diagnosis of syndrome elements. The correlation between TCM syndrome factors of MCI aged people and influencing factors was analyzed by descriptive analysis, chi square test, rank test and other methods. Results: the characteristics of TCM syndrome in 1.MCI elderly were mainly liver (150,49.02 %), 148,48.37%, followed by 95,31.05%, 62,20.26%, and 57,18.63%; the main deficiency syndrome is Yang deficiency (177,57.84%), blood deficiency (170,55.56%), yin deficiency (164,53.59%), and Qi deficiency (156,50.98%); the main real syndrome is the relationship between phlegm (103,33.66%), Qi Stagnation (100,32.68%), wet (70,22.88%), heat (41,13.40%) and sex: The frequency of female liver, kidney and heart syndrome was higher than that of male (P0.05); in the degree of diagnosis of cardiac syndrome, women were lower than men in mild frequency, moderate and severe frequency was higher (P0.05).3. syndrome and age: the frequency of MCI aged 70 and above in Yang deficiency, blood deficiency, yin deficiency and Qi deficiency syndrome was higher than that of 60-69 years old MCI elderly (P0.05); in Yang Deficiency Syndrome The grade of MCI aged 60-69 years old was mild, the moderate frequency was higher than that of MCI older than 70 years old, and the severe frequency was low (P0.05). In the degree of diagnosis of blood deficiency syndrome, the mild frequency distribution of MCI aged 60-69 years was higher than that of MCI older people above 70 years old, and the moderate and severe frequency distribution was low (P0.05).4. syndrome and smoking. Department: the relationship between high (P0.05).5. (P0.05).5. syndrome and alcohol consumption of elderly people who have no smoking habit in the frequency of blood deficiency and Qi deficiency than that of smoking habits: in the degree of liver syndrome, the mild frequency distribution of MCI aged people with drinking habits is lower than that of MCI elderly people who have no drinking habits, and the moderate and severe frequency distribution is in the moderate and severe frequency. High (P0.05); in the severity of qi deficiency syndrome, the mild frequency distribution of MCI aged people with drinking habit was high, and the relationship between the moderate and severe frequency distribution was low (P0.05).6. syndrome and the family history of dementia: there was no statistical difference between the MCI elderly in the history of different family dementia and the degree of diagnosis of TCM syndrome. The relationship between the significance (P0.05).7. syndrome and the history of hypertension: the MCI elderly in the history of hypertension are higher in the severity of the diagnosis of yin deficiency syndrome than in the mild frequency distribution of the MCI elderly without the history of hypertension. The relationship between the moderate and severe frequency distribution is the relationship between the low (P0.05).8. syndrome and the irregular movement: the regular movement of MCI The relationship between the elderly people with kidney, heart, heart, heart (brain), Yang deficiency, blood deficiency and Qi deficiency syndrome is lower (P0.05).9. syndrome factor and occupational labor mode of MCI elderly people with no regular movement: the MCI elderly with mental labor are lower than those of MCI elderly with physical labor (P0.05) in the frequency of Yang deficiency syndrome, and the severity of the diagnosis of bile and qi stagnation is in the degree of severity. MCI elderly people with physical labor as the main mode of labor are higher in moderate and severe frequency than those of MCI with mental labor as the main working mode of labor, and the light frequency distribution is low (P0.05). Conclusion: the main symptoms of 1.MCI in the elderly are liver, kidney, heart, heart (brain) and gallbladder, and the main syndromes of the disease are Yang deficiency and blood deficiency, Yin deficiency, Qi deficiency, phlegm, qi stagnation, dampness, and heat.2.MCI are related to sex, age, smoking, drinking, history of hypertension, irregular movement and occupational labor.

【學位授予單位】：福建中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R277.7

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