本文選題：痰熱清注射液 + 慢性阻塞性肺疾病急性加重期��； 參考：《廣西中醫(yī)藥大學(xué)學(xué)報(bào)》2017年01期

【摘要】：[目的]觀察痰熱清注射液對慢性阻塞性肺疾病(COPD)急性加重期痰熱郁肺證患者血清超敏C反應(yīng)蛋白(hsCRP)、白細(xì)胞介素-6(IL-6)、白細(xì)胞介素-10(IL-10)的影響。[方法]采取隨機(jī)對照的方法將70例COPD急性加重期痰熱郁肺證患者隨機(jī)分為對照組和治療組,每組各35例,對照組給予抗感染、止咳化痰、解痙平喘等常規(guī)治療,治療組在對照組常規(guī)治療基礎(chǔ)上加用痰熱清注射液20 ml/d治療,療程為7 d。分別于治療前后進(jìn)行癥候評分及檢測血清中hs-CRP、IL-6、IL-10水平。[結(jié)果]治療組總有效率為94.3%,對照組總有效率為77.1%,兩組療效對比,差異具有統(tǒng)計(jì)學(xué)意義(P0.05);治療組治療后癥狀、體征積分明顯下降,且優(yōu)于對照組(P0.05);兩組治療后血清hs-CPR、IL-6水平降低(P0.05),血清IL-10水平升高(P0.05),且治療組優(yōu)于對照組(P0.05)。[結(jié)論]痰熱清注射液可降低COPD急性加重期痰熱郁肺證患者血清中hs-CRP、IL-6水平,提高IL-10水平,治療COPD急性加重期痰熱郁肺證患者有明確的療效。
[Abstract]:[objective] to observe the effect of Tanreqing injection on serum hypersensitive C-reactive protein (hsCRPN), interleukin-6 (IL-6) and interleukin-10 (IL-10) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPDD). [methods] 70 patients with acute exacerbation of COPD were randomly divided into two groups: control group (n = 35) and treatment group (n = 35). The control group was given routine treatment such as anti-infection, relieving cough and eliminating phlegm, and relieving spasm and asthma. The treatment group was treated with Tanreqing injection for 20 ml/d on the basis of routine treatment in the control group for 7 days. The symptom score and the level of hs-CRP IL-6 and IL-10 in serum were measured before and after treatment. [results] the total effective rate of the treatment group was 94.3 and the total effective rate of the control group was 77.1. The difference between the two groups was statistically significant (P 0.05). It was better than the control group (P 0.05), and the serum hs-CPR IL-6 level was lower than that of the control group (P 0.05), the serum IL-10 level was increased (P 0.05), and the treatment group was superior to the control group (P 0.05). [conclusion] Tanreqing injection can decrease the serum hs-CRP IL-6 level and increase the IL-10 level in the patients with phlegm-heat stagnation lung syndrome in acute exacerbation of COPD. It has a definite curative effect on the patients with phlegm-heat stagnation lung syndrome in acute exacerbation of COPD.
【作者單位】： 廣西中醫(yī)藥大學(xué)附屬瑞康醫(yī)院;
【分類號】：R259

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本文編號：1856093