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補(bǔ)腎活血湯治療人流術(shù)后腎虛血瘀型月經(jīng)過少的臨床研究

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  本文選題:人流術(shù)后 + 月經(jīng)過少。 參考:《福建中醫(yī)藥大學(xué)》2016年碩士論文


【摘要】:目的:分析補(bǔ)腎活血湯對改善患者臨床癥狀,增加經(jīng)量、行經(jīng)時(shí)間、子宮內(nèi)膜厚度,改善子宮螺旋動脈血流方面的作用;客觀評價(jià)補(bǔ)腎活血湯治療人流術(shù)后腎虛血瘀型月經(jīng)過少的臨床療效。方法:收集符合納入標(biāo)準(zhǔn)的人流術(shù)后腎虛血瘀型月經(jīng)過少的患者共60例,隨機(jī)分為采用補(bǔ)腎活血湯治療的治療組;戊酸雌二醇、黃體酮膠囊序貫治療的對照組,每組各30例。觀察比較治療前后兩組患者經(jīng)量、行經(jīng)時(shí)間、子宮內(nèi)膜厚度、子宮螺旋動脈血流參數(shù)、中醫(yī)證候積分的差異;比較兩組中醫(yī)證候療效及綜合療效的差異。結(jié)果:1.經(jīng)量的比較:兩組治療前后月經(jīng)失血圖積分比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組月經(jīng)失血圖積分組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05),說明兩組治療后均可增加經(jīng)量,治療組優(yōu)于對照組。2.行經(jīng)時(shí)間的比較:兩組行經(jīng)時(shí)間治療前后比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組行經(jīng)時(shí)間組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05),說明兩組治療后均可延長行經(jīng)時(shí)間,治療組優(yōu)于對照組。3.子宮內(nèi)膜厚度的比較:兩組治療前后子宮內(nèi)膜厚度比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組子宮內(nèi)膜厚度組間比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05),說明兩組治療后均可增加患者子宮內(nèi)膜厚度,作用無差異。4.子宮螺旋動脈血流參數(shù)的比較:兩組治療前后子宮螺旋動脈S/D、阻力指數(shù)、搏動指數(shù)比較,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組子宮螺旋動脈S/D、阻力指數(shù)、搏動指數(shù)組間比較,差異均有統(tǒng)計(jì)學(xué)意義(P0.05),說明治療后兩組的子宮螺旋動脈血流均得到改善,治療組優(yōu)于對照組。5.中醫(yī)證候積分的比較:兩組治療前后中醫(yī)證候積分比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后兩組中醫(yī)證候積分組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05),說明兩組治療后均可改善患者臨床癥狀,治療組優(yōu)于對照組。6.中醫(yī)證候療效的比較:治療組中醫(yī)證候總有效率為96.67%;對照組中醫(yī)證候總有效率為83.33%。兩組中醫(yī)證候療效比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。說明治療組中醫(yī)證候療效優(yōu)于對照組。7.綜合療效比較:治療組綜合療效總有效率為96.7%,對照組綜合療效總有效率為83.33%,兩組綜合療效比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。說明治療組綜合療效優(yōu)于對照組。結(jié)論:運(yùn)用補(bǔ)腎活血湯治療人流術(shù)后腎虛血瘀型月經(jīng)過少,在增加子宮內(nèi)膜厚度方面與對照組(戊酸雌二醇+黃體酮膠囊)治療療效相當(dāng);但在改善臨床癥狀、增加經(jīng)量、延長經(jīng)期、改善子宮螺旋動脈血流方面,優(yōu)于對照組(戊酸雌二醇+黃體酮膠囊)治療;顯示了中醫(yī)藥治療本病的優(yōu)越性,為中醫(yī)辨證治療本病提供客觀依據(jù)。
[Abstract]:Objective: to analyze the effect of Bushen Huoxue decoction on improving clinical symptoms, increasing menstrual volume, menstrual time, endometrial thickness and improving the blood flow of uterine spiral artery. Objective to evaluate the clinical efficacy of Bushen Huoxue decoction (BUST) in the treatment of deficiency of kidney and blood stasis type of menstruation. Methods: a total of 60 patients with insufficient menstruation of kidney deficiency and blood stasis type were collected and randomly divided into treatment group treated with Bushen Huoxue decoction and control group treated with estradiol valerate and progesterone capsules. To observe and compare the difference between the two groups before and after treatment in terms of menstrual volume, menstrual time, endometrial thickness, uterine spiral artery blood flow parameters, TCM syndromes integral, and compare the curative effect and comprehensive curative effect of TCM syndromes between the two groups. The result is 1: 1. Comparison of the two groups before and after treatment, the difference was statistically significant (P 0.05); after treatment, the difference was statistically significant (P 0.05), indicating that both groups could increase the menstrual volume after treatment. The treatment group was superior to the control group. Comparison of menstrual time: there was a significant difference between the two groups before and after treatment, and the difference between the two groups after treatment was statistically significant (P 0.05), indicating that the menstrual time of the two groups could be prolonged after treatment. The treatment group was superior to the control group. Comparison of endometrial thickness: there was significant difference in endometrial thickness between the two groups before and after treatment (P 0.05). The difference was not statistically significant (P 0.05), indicating that both groups could increase the endometrial thickness after treatment. Comparison of blood flow parameters of uterine spiral artery: there were statistically significant differences in uterine spiral artery S / D, resistance index and pulsatile index between the two groups before and after treatment, and there were significant differences between the two groups before and after treatment (P < 0.05); after treatment, there was a comparison between the two groups of uterine spiral artery S / D, resistance index and pulsatile index. The difference was statistically significant (P 0.05), indicating that the uterine spiral artery blood flow of the two groups were improved after treatment, and the treatment group was better than the control group. 5. Comparison of TCM syndromes integral: the difference between the two groups before and after treatment was statistically significant (P 0.05); after treatment, the difference was statistically significant between the two groups, indicating that the two groups could improve the clinical symptoms of the patients after treatment. The treatment group was superior to the control group. Comparison of TCM syndrome efficacy: the total effective rate of TCM syndrome in the treatment group was 96.677.The total effective rate of TCM syndrome in the control group was 83.33. The difference between the two groups was statistically significant (P 0.05). It shows that the therapeutic effect of TCM syndrome in the treatment group is better than that in the control group. Comprehensive curative effect comparison: the total effective rate of comprehensive curative effect in the treatment group was 96.77.The total effective rate in the control group was 83.33.The difference between the two groups was statistically significant (P 0.05). The comprehensive curative effect of the treatment group was better than that of the control group. Conclusion: the application of Bushen Huoxue decoction in the treatment of excessive menstruation due to deficiency of kidney and blood stasis after abortion is comparable to that of control group (estradiol valerate progesterone capsule) in increasing the thickness of endometrium, but it can improve the clinical symptoms and increase the amount of menstruation. Prolonging menstrual period and improving uterine spiral artery blood flow were superior to control group (estradiol valerate progesterone capsule), which showed the superiority of traditional Chinese medicine in treating this disease and provided objective basis for TCM syndrome differentiation treatment.
【學(xué)位授予單位】:福建中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2016
【分類號】:R271.111

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