自擬愈潰方維持緩解脾腎陽(yáng)虛型潰瘍性結(jié)腸炎的臨床療效研究
發(fā)布時(shí)間:2018-05-04 07:02
本文選題:自擬愈潰方 + 潰瘍性結(jié)腸炎; 參考:《遼寧中醫(yī)藥大學(xué)》2016年碩士論文
【摘要】:目的:觀察自擬愈潰方加減維持緩解脾腎陽(yáng)虛型潰瘍性結(jié)腸炎的臨床療效。方法:41例脾腎陽(yáng)虛型潰瘍性結(jié)腸炎患者隨機(jī)分為兩組,治療組20例,給予自擬愈潰方加減口服,對(duì)照組21例,給予美沙拉秦緩釋顆粒劑(艾迪莎)口服。兩組均隨訪治療1年。觀察兩組患者維持緩解率、依從性及不良反應(yīng)發(fā)生情況。結(jié)果:1.試驗(yàn)結(jié)束時(shí),治療組和對(duì)照組分別有15例和10例處于維持緩解期,Kaplan-Meier生存曲線顯示治療組在潰瘍性結(jié)腸炎維持緩解方面略優(yōu)于對(duì)照組,但差異無(wú)統(tǒng)計(jì)學(xué)意義。2.兩組患者均無(wú)不良反應(yīng)發(fā)生。3.依從性方面,治療組脫落2例,對(duì)照組脫落6例,差異無(wú)統(tǒng)計(jì)學(xué)差異。結(jié)論:1.自擬愈潰方維持緩解脾腎陽(yáng)虛型潰瘍性結(jié)腸炎是有效的,在抗復(fù)發(fā)方面療效確切;2.自擬愈潰方維持緩解脾腎陽(yáng)虛型潰瘍性結(jié)腸炎是安全的。
[Abstract]:Objective: to observe the clinical effect of self-made Yukui prescription on relieving ulcerative colitis with deficiency of spleen and kidney yang. Methods 41 patients with ulcerative colitis with deficiency of spleen and kidney yang were randomly divided into two groups: the treatment group (n = 20) was treated with self-made Yukui decoction, and the control group (n = 21) was given mezalazine sustained release granule (Adiza). Both groups were followed up for 1 year. The maintenance remission rate, compliance and adverse reactions were observed in both groups. The result is 1: 1. At the end of the trial, 15 cases in the treatment group and 10 cases in the control group were in the maintenance stage of remission. Kaplan-Meier survival curve showed that the treatment group was slightly superior to the control group in the maintenance and remission of ulcerative colitis, but the difference was not statistically significant. There were no adverse reactions. 3. 3 in both groups. In terms of compliance, there were 2 cases in treatment group and 6 cases in control group. Conclusion 1. The self-made Yukui recipe is effective in relieving ulcerative colitis with deficiency of spleen and kidney yang and is effective in anti-recurrence. Self-made Yukui recipe is safe to relieve ulcerative colitis due to deficiency of spleen and kidney yang.
【學(xué)位授予單位】:遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類號(hào)】:R259
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本文編號(hào):1842064
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