發(fā)布時(shí)間：2018-05-02 17:34

  本文選題：偏頭痛 + 針刺��； 參考：《重慶醫(yī)科大學(xué)學(xué)報(bào)》2017年10期

【摘要】：目的:系統(tǒng)評(píng)價(jià)針刺對(duì)比藥物對(duì)偏頭痛的預(yù)防治療療效及安全性,為針刺的臨床應(yīng)用提供循證依據(jù)。方法:檢索Pubmed、The Cochrane library、EMBASE、CBM、VIP、Wan Fang Data和CNKI,檢索時(shí)間為建庫至2015年12月,收集針刺和藥物對(duì)偏頭痛的預(yù)防治療的隨機(jī)對(duì)照研究。篩選合格的文獻(xiàn)并提取相關(guān)數(shù)據(jù),結(jié)局?jǐn)?shù)據(jù)按照隨訪時(shí)間分為隨機(jī)后3~4月和隨機(jī)后5~6月2個(gè)亞組,最后進(jìn)行Meta分析。結(jié)果:根據(jù)納入排除標(biāo)準(zhǔn)篩選后共納入研究7項(xiàng),包含1285名偏頭痛患者。Meta分析結(jié)果顯示,針刺組和藥物組在隨機(jī)分組后隨訪3~4月的治療有效率(RR=1.24,95%CI=1.04~1.47,P=0.020)、偏頭痛天數(shù)(SMD=-0.30,95%CI=-0.45~-0.16,P=0.000)、頭痛程度(SMD=-0.32,95%CI=-0.52~-0.11,P=0.000)有統(tǒng)計(jì)學(xué)差異,隨機(jī)分組后隨訪5~6月的偏頭痛天數(shù)(MD=-0.66,95%CI=-1.18~-0.13,P=0.010)、頭痛程度(SMD=-0.31,95%CI=-0.47~-0.15,P=0.000)也有統(tǒng)計(jì)學(xué)意義;而隨機(jī)分組后隨訪5~6月的治療有效率(RR=1.18,95%CI=0.97~1.43,P=0.110)2組間無統(tǒng)計(jì)學(xué)差異;因此針刺組相對(duì)藥物治療組,治療有效率更大、偏頭痛天數(shù)更少,頭痛程度更輕。不良反應(yīng)率由于異質(zhì)性較大(I2=77%),通過描述性分析認(rèn)為針刺不良反應(yīng)率較藥物小。結(jié)論:針刺相對(duì)藥物對(duì)偏頭痛的預(yù)防治療有更好的治療效應(yīng)及安全性,但還需要更多的優(yōu)質(zhì)試驗(yàn)進(jìn)一步增強(qiáng)循證依據(jù)。
[Abstract]:Objective: to evaluate the efficacy and safety of acupuncture contrast drugs in the prevention and treatment of migraine, and to provide evidence-based basis for the clinical application of acupuncture. Methods: the Cochrane libraryary EMBASE (CBM) VIPA Wan Fang Data and CNKI were searched. The retrieval time was established until December 2015. The randomized controlled study of acupuncture and drug therapy for migraine was collected. According to the follow-up time, the outcome data were divided into two subgroups: random 3 ~ 4 months and random 5 ~ 6 months. Finally, Meta analysis was performed. Results: according to the exclusion criteria, a total of 7 subjects were included in the study, including 1285 migraine patients. Meta-analysis showed that, 閽堝埡緇勫拰鑽墿緇勫湪闅忔満鍒嗙粍鍚庨殢璁，

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