本文選題：復(fù)方四黃膏 + 早期肛裂　； 參考：《華北理工大學》2016年碩士論文

【摘要】：目的觀察復(fù)方四黃膏治療早期肛裂的臨床效果,評價其對早期肛裂的止血,止痛,改善便秘,促進愈合以及裂口抑菌作用。方法選取符合標準的150例早期肛裂患者,根據(jù)隨機數(shù)字表選取一行,數(shù)字除以3,余數(shù)為0為復(fù)方四黃膏組,余數(shù)為1為肛泰軟膏組,余數(shù)為2為肛泰栓組,多余n例數(shù)則從中選1例,在隨機數(shù)字表中選下一隨機數(shù)除以n,所得余數(shù)為編號順序,將此順序號調(diào)整到例數(shù)較少組,直到三組例數(shù)相同。三組患者應(yīng)用30℃溫生理鹽水清洗患處,干凈脫脂棉擦干后,復(fù)方四黃膏組取復(fù)方四黃膏1g涂于裂口處,干凈脫脂棉球固定;肛泰軟膏組取肛泰軟膏1g涂于裂口處,干凈脫脂棉球固定;肛泰栓組取肛泰栓1枚納肛,干凈脫脂棉球固定。每日兩次,其中一次于早晨便后,一次為睡前。從用藥第一天開始,采用視覺模糊評分法與WHO評分法結(jié)合觀察統(tǒng)計患者第1、3、7天各疼痛程度例數(shù);記錄三組出血停止時間,便秘改善時間,裂口愈合時間;統(tǒng)計三組裂口愈合中痊愈、有效以及無效例數(shù),分析比較三組有效率;通過抑菌實驗檢測抑菌環(huán)直徑并評分,統(tǒng)計第1、3、7天各評分例數(shù)比較三組對于細菌的抑制作用。對上述觀察指標進行統(tǒng)計學分析,并進行兩兩比較,分析統(tǒng)計結(jié)果。結(jié)果治療后1d三組疼痛程度比較,差異無統(tǒng)計學意義;治療后3、7d三組疼痛程度,差異有統(tǒng)計學意義,復(fù)方四黃膏組止痛效果強于肛泰軟膏組,強于肛泰栓組;兩兩比較顯示,復(fù)方四黃膏組止痛效果強于肛泰軟膏組,強于肛泰栓組,肛泰軟膏組強于肛泰栓組;三組便血停止時間比較,差異有統(tǒng)計學意義,復(fù)方四黃膏組止血效果強于肛泰軟膏組,強于肛泰栓組;兩兩比較結(jié)果顯示復(fù)方四黃膏組強于肛泰軟膏組,強于肛泰栓組;肛泰軟膏組強于肛泰栓組;裂口愈合時間三組比較,差異有統(tǒng)計學意義,復(fù)方四黃膏組促進裂口愈合作用強于肛泰軟膏組,強于肛泰栓組;兩兩比較結(jié)果顯示復(fù)方四黃膏組促進裂口愈合作用強于肛泰軟膏組,強于肛泰栓組;肛泰軟膏組強于肛泰栓組;便秘改善時間三組比較顯示差異有統(tǒng)計學意義,肛泰栓組對于便秘的改善作用強于肛泰軟膏組,強于肛泰栓組;兩兩比較結(jié)果顯示復(fù)方四黃膏組與肛泰軟膏組對于便秘改善作用差異無統(tǒng)計學意義;抑菌實驗三組比較,第1天,差異有統(tǒng)計學意義,復(fù)方四黃膏組抑菌作用強于肛泰軟膏組,強于肛泰栓組;兩兩比較結(jié)果顯示復(fù)方四黃膏組抑菌作用強于肛泰軟膏組,強于肛泰栓組;肛泰軟膏組抑菌作用與肛泰栓組無差異;第3、7天,差異無統(tǒng)計學意義;三組總療效比較,差異有統(tǒng)計學意義,且三組出現(xiàn)不良反應(yīng)者未經(jīng)治療自愈。結(jié)論復(fù)方四黃膏具有止血、減輕疼痛、促進愈合、改善便秘、增加治愈效果的功效,可以有效治療早期肛裂便血、疼痛、便秘的癥狀,對于裂口感染具有抑菌作用,臨床療效良好,經(jīng)濟實用,值得推廣使用。
[Abstract]:Objective to observe the clinical effect of compound Sihuang ointment in the treatment of early anal fissure, and to evaluate its effect on hemostasis, pain relief, constipation improvement, healing and fissure bacteriostasis. Methods 150 patients with early anal fissure were selected. According to the random number table, the number was divided by 3, the remainder was 0 as the compound Sihuang ointment group, the remainder was 1 as the anal Tai ointment group, and the remaining number was 2 in the Shatai suppository group. In the random number table, the next random number divided by n is selected, and the remainder is in the numbering order, and the sequence number is adjusted to the group with fewer cases until the three groups have the same number. The patients in the three groups were cleaned with warm saline at 30 鈩，

本文編號：1802232