本文選題：潰瘍性結(jié)腸炎 + 緩解期��； 參考：《中華中醫(yī)藥雜志》2017年07期

【摘要】：目的:對(duì)中醫(yī)特色慢病管理治療潰瘍性結(jié)腸炎(UC)的近期、遠(yuǎn)期療效、預(yù)防復(fù)發(fā)及其安全性作出科學(xué)評(píng)價(jià)。方法:采用隨機(jī)、對(duì)照的方法,選擇UC緩解期患者60例,隨機(jī)分為兩組:治療組給予中醫(yī)特色慢病管理模式,對(duì)照組給予目前西醫(yī)對(duì)維持緩解UC有效的所有藥物作為對(duì)照,其中,以艾迪莎(美沙拉嗪)為主。療程均為6個(gè)月,每月隨訪記錄癥狀,主要觀察臨床癥狀療效、復(fù)發(fā)率、臨床活動(dòng)指數(shù)及內(nèi)鏡指數(shù)的變化、生活質(zhì)量、不良反應(yīng)和費(fèi)用。結(jié)果:治療6個(gè)月后,治療組與對(duì)照組相比,復(fù)發(fā)率相當(dāng)且不良反應(yīng)少,改善癥狀持久穩(wěn)定,并改善貧血等全身癥狀,提高腸道黏膜愈合質(zhì)量,減少醫(yī)療費(fèi)用,提高生活質(zhì)量。結(jié)論:中醫(yī)慢病管理治療UC緩解期有一定的優(yōu)勢(shì)和發(fā)展?jié)摿?具有價(jià)廉、有效、安全等優(yōu)點(diǎn),值得進(jìn)一步深入研究、探討并推廣。
[Abstract]:Objective: to evaluate the short term and long term curative effect, prevention and safety of ulcerative colitis (UC) treated by management of characteristic chronic diseases of traditional Chinese medicine (TCM). Methods: sixty UC patients in remission period were randomly divided into two groups: the treatment group was treated with traditional Chinese medicine (TCM) characteristic chronic disease management model, and the control group was treated with all the drugs that were effective in maintaining the remission of UC. Among them, the main is Edessa (Mesalazine). The course of treatment was 6 months. The symptoms were recorded every month. The changes of clinical symptoms, recurrence rate, clinical activity index and endoscopic index, quality of life, adverse reactions and expenses were observed. Results: after 6 months of treatment, the recurrence rate of the treatment group was equal to that of the control group, and the adverse reactions were less, the symptoms were improved and the systemic symptoms such as anemia were improved, the healing quality of intestinal mucosa was improved, the medical expenses were reduced, and the quality of life was improved. Conclusion: the management of chronic diseases in TCM has some advantages and development potential in the remission period of UC. It has the advantages of cheap, effective and safe, which is worthy of further study, discussion and popularization.
【作者單位】： 武漢市中西醫(yī)結(jié)合醫(yī)院消化科;廣東省中醫(yī)院廣州中醫(yī)藥大學(xué)第二臨床醫(yī)學(xué)院;
【基金】：國(guó)家中醫(yī)臨床研究基地業(yè)務(wù)建設(shè)科研專項(xiàng)課題(No.JDZX2012085)~~
【分類號(hào)】：R259

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