本文選題：金玉教授 + 學(xué)術(shù)思想��； 參考：《北京中醫(yī)藥大學(xué)》2016年博士論文

【摘要】：目的：1.收集、整理、總結(jié)、繼承發(fā)揚(yáng)金玉教授的學(xué)術(shù)思想特點(diǎn)及臨床經(jīng)驗(yàn)和技術(shù)專長。2.通過以蘇格木勒-7味丸為主要方藥,評價(jià)其治療“赫依布日勒得森病”的療效及安全性,進(jìn)一步證明蒙藥治療“赫依布日勒得森病”的臨床療效,提高“赫依布日勒得森病”的蒙醫(yī)藥診治及臨床治療知識,用科學(xué)的方法證明其療效,為臨床用藥提供可靠的科學(xué)依據(jù)。方法：1.根據(jù)跟師筆記及典型醫(yī)案、老師的專著、科研成果等系統(tǒng)回顧導(dǎo)師的學(xué)術(shù)思想淵源,充分掌握指導(dǎo)老師的臨床經(jīng)驗(yàn)、診病特點(diǎn)、用藥經(jīng)驗(yàn)等,全面收集、整理、繼承金玉教授的學(xué)術(shù)思想及臨床經(jīng)驗(yàn)。(1)收集、整理指導(dǎo)老師的學(xué)術(shù)思想如下：①治療“布日勒德森病”要以“血以調(diào)為補(bǔ)得”,以“調(diào)氣血,熱寒平衡交替施治”理念：②注重赫依其蘇,強(qiáng)調(diào)平衡及滋補(bǔ)：③改善胃、脾、心、肝、腎的功能,達(dá)到平衡子宮及卵巢的功能；④注重蒙醫(yī)的整體觀思想及治療婦科病時(shí)與婦女特性相結(jié)合為主：⑤強(qiáng)調(diào)改善腎臟功能,增加精華治療疾病的目的：⑥注重胃及脾的功能：⑦根據(jù)癥狀引導(dǎo)治療：⑧臨床治療中注重靈活應(yīng)用藥物：⑨強(qiáng)調(diào)骨骼損傷時(shí)分期辯證用藥。(2)收集、整理指導(dǎo)老師的臨床經(jīng)驗(yàn)如下：本研究中主要整理了指導(dǎo)老師治療原發(fā)性痛經(jīng)、子宮出血、不孕癥、子宮肌瘤、外陰白斑、“赫依布日勒得森病”、乳腺的齊蘇布日勒德森病等治療婦科疾病的臨床經(jīng)驗(yàn)。整理了治療關(guān)節(jié)黃水病、心律不齊、胃病、肺赫依為主的咳嗽病、遺精病、齊蘇希日型頭痛病等其他系統(tǒng)疾病的臨床經(jīng)驗(yàn)。2.在本研究中經(jīng)過整理研究指導(dǎo)老師的學(xué)術(shù)思想和臨床經(jīng)驗(yàn),并結(jié)合本人的臨床專業(yè),觀察以蘇格木勒-7味丸為主要方藥治療“赫依布日勒得森病”的臨床療效及安全性。3.選取符合納入標(biāo)準(zhǔn)的80例“巴達(dá)干赫依型”赫依布日勒得森病患者,隨機(jī)分為治療組及對照組,每組40例,治療組早：蘇格木勒-7味丸15粒飯前口服,中午：通拉嘎-5味丸15粒飯后口服,晚：蘇格木勒-7味丸15粒以阿嘎如-35味散5克送服。對照組：中藥舒更片,3片日三次飯后溫水送服。總療程為8周,觀察指標(biāo)為患者一般信息、生命體征；安全指標(biāo)有肝腎功能、血常規(guī)；療效性指標(biāo)為各種癥狀變化及女性激素E2(雌二醇),FSH(卵泡刺激素),LH(黃體生成激素)的變化等。各指標(biāo)在治療前后檢查一次,并進(jìn)行組內(nèi)治療前后及組間對比分析。結(jié)果：1.收集、整理指導(dǎo)老師的學(xué)術(shù)思想如下：治療“布日勒德森病”要以“血以調(diào)為補(bǔ)得”,以“調(diào)氣血,熱寒平衡交替施治”理念：注重赫依其蘇,強(qiáng)調(diào)平衡及滋補(bǔ)；改善胃、脾、心、肝、腎的功能,達(dá)到平衡子宮及卵巢的功能；注.重蒙醫(yī)的整體觀思想及治療婦科病時(shí)與婦女特性相結(jié)合為主：強(qiáng)調(diào)改善腎臟功能,增加精華治療疾病的目的：注重胃及脾的功能：根據(jù)癥狀引導(dǎo)治療：臨床治療中注重靈活應(yīng)用藥物：強(qiáng)調(diào)骨骼損傷時(shí)分期辯證用藥。2.收集、整理指導(dǎo)老師的臨床經(jīng)驗(yàn)如下：本研究中主要整理了指導(dǎo)老師治療原發(fā)性痛經(jīng)、子宮出血、不孕癥、子宮肌瘤、外陰白斑、“赫依布日勒得森病”、乳腺的齊蘇布日勒德森病等治療婦科疾病的臨床經(jīng)驗(yàn)。整理了治療關(guān)節(jié)黃水病、心律不齊、胃病、肺赫依為主的咳嗽病、遺精病、齊蘇希日型頭痛病等其他系統(tǒng)疾病的臨床經(jīng)驗(yàn)。3.以蘇格木勒-7味丸為主的蒙藥治療“赫依布日勒得森病”的療效平價(jià)顯示：治療組總有效率為94.59%,對照組為84.21%,兩組間有顯著性差異(P0.05),治療組優(yōu)于對照組；兩組癥狀的總數(shù)對比后,治療前兩組無顯著性差異(P0.05),治療后治療組改善癥狀方面優(yōu)于對照組；各癥狀兩組除了白帶增多外其他癥狀治療前后有顯著性差異(P0.05)；兩組E2、FSH、LH激素水平治療前對比無顯著性差異(P0.05),治療后兩組的E2均升高,FSH、LH水平均下降,治療組作用優(yōu)于對照組(P0.05)；血常規(guī),肝腎功能等安全性指標(biāo)檢查結(jié)果顯示：治療前后組內(nèi)對比和組間對照無顯著性差異(P0.05)。結(jié)論：1.傳承名老蒙醫(yī)學(xué)術(shù)思想是發(fā)展蒙醫(yī)藥的重要途徑。收集、整理并總結(jié)金玉教授的學(xué)術(shù)思想和臨床經(jīng)驗(yàn)、用藥手法,對蒙醫(yī)婦科學(xué)術(shù)的發(fā)展具有重要的意義,并對婦科疑難病的診治將起到一定的推動(dòng)作用。2.指導(dǎo)老師對“赫依布日勒得森病”的診治方面具有獨(dú)特的見解和臨床經(jīng)驗(yàn),并療效可靠。3.本研究結(jié)果顯示：蒙藥蘇格木勒-7味丸為主要方藥的蒙藥治療“赫依布日勒得森病”的療效確切,且在改善各種癥狀優(yōu)于對照組(舒更片組)；蒙藥組對E2、FSH、LH激素水平改善優(yōu)于對照組。4.以蒙藥蘇格木勒-7味丸為主要方藥的蒙藥治療“赫依布日勒得森病”方法安全且無毒副作用,臨床應(yīng)推廣應(yīng)用。創(chuàng)新點(diǎn)：1.首次全面系統(tǒng)整理總結(jié)了金玉教授的學(xué)術(shù)思想及臨床經(jīng)驗(yàn),尤其總結(jié)了辯證診治婦科病的獨(dú)到見解及獨(dú)特的診療特色,對蒙醫(yī)婦科學(xué)術(shù)發(fā)展具有重要意義,同時(shí)對蒙醫(yī)婦科疑難疾病的治療將起到一定的推動(dòng)作用。2.根據(jù)古籍文獻(xiàn)記載及指導(dǎo)老師對本病的蒙醫(yī)藥診治的見解和觀點(diǎn)及臨床經(jīng)驗(yàn),創(chuàng)新性提出了自己的觀點(diǎn)。①“赫依布日勒得森病”病因雖然是“巴達(dá)干赫依”但是赫依增多,齊蘇滋補(bǔ)缺乏,赫依齊蘇失調(diào)也是主要的病因。②方面食用生冷食物及受寒冷、淋雨等使體內(nèi)“赫依、希日、巴達(dá)干”失調(diào),引起“赫依布日勒得森病”。病根隨血流到達(dá)各臟腑形成全身性疾病。另一方面社會及家庭的因素使思想壓力過重,使病情加重。③隨著人的年齡增長各種臟腑功能減弱,赫依齊蘇滋補(bǔ)缺乏引起,子宮及卵巢的功能衰退,赫依齊蘇失調(diào)引起發(fā)病。④治療：降巴達(dá)干赫依,調(diào)節(jié)赫依齊蘇失調(diào),改善腎功能,根據(jù)癥狀辯證施治為原則,治療藥物的選擇上把晚上口服的蘇格木勒-7味丸以調(diào)節(jié)依齊蘇失調(diào),改善睡眠的阿嘎如-35味散為引子,為達(dá)到徹底治療本病的基礎(chǔ)上確立了該項(xiàng)研究,用科學(xué)的方法證明了其療效。3.首次科學(xué)研究證明了蒙藥蘇格木勒-7味丸為主要方藥,治療“赫依布日勒得森病”的臨床療效。
[Abstract]:Objective: 1. collecting, sorting, summarizing, inheriting the academic thought characteristics, clinical experience and technical expertise of Professor Jinyu,.2. through using Suge Mu Le -7 pill as the main prescription to evaluate the curative effect and safety of the treatment of "heyllolde disease", and further prove the clinical effect of the Mongolian medicine for the treatment of "heyllolde disease". The knowledge of medical treatment and clinical treatment of "Helby Le de Sen's disease" has been proved by scientific methods to provide a reliable scientific basis for clinical medication. Methods: 1. according to the notes of the teachers and typical medical cases, teachers' monographs, scientific research results and so on, the academic thought origin of tutors is reviewed, and the instructor's clinical practice is fully mastered. Experience, diagnosis characteristics, use of drug experience and so on, comprehensive collection, sorting, and inheriting the academic thought and clinical experience of Professor Jinyu. (1) collect and organize the teacher's academic ideas as follows: (1) to treat "brierson disease" with "blood to be mended", "Qi and blood, heat and cold balance alternately governing" concept: (2) pay attention to Heyi Su, strong Balance and nourish: improve the function of the stomach, spleen, heart, liver and kidney to balance the function of the uterus and the ovary; (4) pay attention to the overall concept of the Mongolian medicine and the combination of the women's characteristics when treating gynecologic diseases: 5. Emphasize the improvement of the function of the kidney and the order of the essence to treat the disease: (6) pay attention to the function of the stomach and the spleen: 7 according to the symptoms. The clinical experience of the teacher is summarized as follows: (2) the clinical experience of the teacher is collated and arranged as follows: This study mainly arranges the instructor to treat primary dysmenorrhea, uterine bleeding, infertility, uterine myoma, vulvar leukoplakia, "leiblaadson disease", mammary gland The clinical experience in the treatment of gynecologic diseases, such as subeb and rerederson's disease, and the clinical experience in the treatment of other systemic diseases such as yellow water disease, arrhythmia, gastric disease, lung HIRI based cough, eachnoid disease, Qi suhi type headache, and other systemic diseases.2. were collated and studied to guide the academic thought and clinical experience of the teacher in this study. According to my clinical specialty, the clinical efficacy and safety of the sugE Koller -7 pill as the main prescription for the treatment of "herb's disease" was observed and the.3. was selected in 80 cases of "Bada kouyi type" patients, which were randomly divided into the treatment group and the treatment group, 40 cases in each group, and the treatment group early: sug Mu Le -7 Oral pill 15 tablets before the meal oral, noon: Tong La GA -5 pill after 15 pills orally, late: sug Mu Le -7 pill 15 pills with a qua like -35 powder 5 grams of clothing. Control group: Chinese medicine Shu more tablets, 3 days after the three meal warm water delivery. The total course of treatment is 8 weeks, the observation index is the patient general information, life signs; safety indicators have liver and kidney function, blood routine; The curative effects were the changes of various symptoms and the changes of female hormone E2 (estradiol), FSH (follicle stimulating hormone), and the changes of LH (luteinizing hormone). Each index was examined once before and after treatment, and before and after treatment in the group, and before and after the comparison and analysis. Results: 1., the academic thoughts of the teacher were collected as follows: the treatment of "buerlerderson's disease" We should take "blood to adjust" to "regulate qi and blood, heat and cold balance alternately" concept: pay attention to h Yi Su, emphasize balance and nourishment, improve the function of stomach, spleen, heart, liver, kidney, to balance the function of the uterus and the ovary; note. The idea of the overall view of the heavy Mongolian medicine and the combination of the treatment and treatment of gynecopathy with the women's characteristics: emphasize the improvement The function of the kidney is to increase the essence of the treatment of the disease: pay attention to the function of the stomach and spleen: according to the symptom guided therapy: pay attention to the flexible application of drugs in the clinical treatment: emphasize the collection of.2. and the clinical experience of the teacher as follows: the master should arrange the instructor to treat the primary dysmenorrhea in this study. Clinical experience in the treatment of gynecologic diseases, such as uterine bleeding, infertility, uterine leiomyoma, leukoplakia, "hiriblerderson's disease", sircilson's disease in the breast, and other clinical experiences in the treatment of gynecologic diseases. The therapeutic parity of.3. with sugolen -7 pill in the treatment of "herb's disease" showed that the total effective rate of the treatment group was 94.59%, the control group was 84.21%, the two groups had significant difference (P0.05), and the treatment group was superior to the control group. After the total of the two groups of symptoms, there was no significant difference between the two groups (P0.05) before treatment and treatment after treatment. The symptoms in the treatment group were better than those in the control group; there were significant differences between the two groups before and after the treatment of other symptoms (P0.05). There was no significant difference in the levels of E2, FSH, and LH in the two groups before treatment (P0.05). After treatment, the E2 of two groups increased, the average of FSH, LH water decreased, and the effect of the treatment group was better than the control group (P0.05); blood routine routine was better than the control group. The results of liver and kidney function and other safety indicators showed that there was no significant difference between the groups before and after treatment and between the groups (P0.05). Conclusion: 1. the thought of inheriting the name and old Mongolian medicine is an important way to develop Mongolian medicine. The exhibition has important significance, and it will play a certain role in the diagnosis and treatment of gynecologic difficult diseases..2. instructor has unique views and clinical experience on the diagnosis and treatment of "hiturdidison disease", and the result is reliable, and the results of.3. study show that Mongolian medicine sug Mu Le -7 pill is the main prescription for the treatment of "heria day". The curative effect of lolson's disease is better than that of the control group (Shu Keng tablet group); the improvement of E2, FSH, LH hormone in the Mongolian medicine group is better than that of the control group.4. with the Mongolian medicine sugolen -7 pill as the main prescription for the treatment of "herb's disease" method and non toxic side effect, and the clinical application should be applied. Innovation point: 1 For the first time, the academic thought and clinical experience of Professor Jinyu were summarized and summarized in a comprehensive system, and the unique views and unique diagnosis and treatment features of the dialectical diagnosis and treatment of gynecologic diseases were summarized, which was of great significance to the academic development of the gynecologic diseases in Mongolian medicine. At the same time, the treatment of the difficult diseases of the Mongolian medicine and gynecologic diseases would be promoted by.2. according to the literature of the ancient books. And instructor's views and clinical experience on the medical and medical treatment of this disease, and the clinical experience, and the innovative point of view. (1) the cause of "hitchisaisson disease" is "Bada dry hitai" but the increase of hitaigan, the deficiency of Qi Su, the disorder of heria Qi Su is also the main cause. On the other hand, the social and family factors make the ideological pressure too heavy and aggravate the condition. The function decline of the uterus and ovary, the disorder caused by the heritii su. 4 treatment: lowering the badha dry hiyi, regulating the disorder of heritii, improving the function of the kidney, improving the function of the kidney, according to the dialectical treatment of symptoms. In order to achieve a thorough treatment of the disease, this study was established, and a scientific method was used to prove that the first scientific study of its curative effect.3. proved that the Mongolian medicine Suge Mu Le -7 pill is the main prescription for the treatment of "herb's disease".

【學(xué)位授予單位】：北京中醫(yī)藥大學(xué)
【學(xué)位級別】：博士
【學(xué)位授予年份】：2016
【分類號】：R29

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