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補(bǔ)腎調(diào)周法聯(lián)合微刺激干預(yù)卵巢低反應(yīng)不孕患者的臨床研究

發(fā)布時(shí)間:2018-04-21 03:30

  本文選題:補(bǔ)腎調(diào)周法 + 微刺激; 參考:《中國中西醫(yī)結(jié)合雜志》2017年05期


【摘要】:目的觀察補(bǔ)腎調(diào)周法聯(lián)合微刺激對(duì)卵巢低反應(yīng)(poor ovarian response,POR)不孕患者臨床療效的影響,探討在POR患者行控制性促排卵周期中運(yùn)用補(bǔ)腎調(diào)周法的可行性和有效性。方法將76例POR患者隨機(jī)分為治療組(38例)和對(duì)照組(38例),對(duì)照組采用微刺激方案,治療組在對(duì)照組基礎(chǔ)上運(yùn)用補(bǔ)腎調(diào)周中藥,療程為3個(gè)月。比較兩組腎陰虛證候改善情況、促性腺激素(Gn)天數(shù)、Gn用量、注射人絨毛膜促性腺激素(HCG)日雌二醇(E_2)水平、獲卵數(shù)、MⅡ卵數(shù)、MⅡ卵受精率、優(yōu)質(zhì)胚胎數(shù)、優(yōu)質(zhì)胚胎率、周期取消率、移植日子宮內(nèi)膜厚度、生化妊娠率和臨床妊娠率。結(jié)果治療組總有效率94.7%(36/38)高于對(duì)照組[76.3%(29/38)](P0.05)。治療后治療組獲卵數(shù)、MⅡ卵數(shù)、優(yōu)質(zhì)胚胎數(shù)、優(yōu)質(zhì)胚胎率及移植日子宮內(nèi)膜厚度均優(yōu)于對(duì)照組(P0.05,P0.01);治療組Gn天數(shù)、Gn用量、HCG日E_2、MⅡ卵受精率、周期取消率、生化妊娠率及臨床妊娠率與對(duì)照組比較,差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論補(bǔ)腎調(diào)周法能增加POR患者超促排卵周期的獲卵數(shù)、MⅡ卵數(shù),提高優(yōu)質(zhì)胚胎率,增加子宮內(nèi)膜厚度,提高妊娠率。
[Abstract]:Objective to observe the effect of tonifying the kidney and regulating the week combined with micro-stimulation on the clinical efficacy of the method of tonifying the kidney and regulating the weeks of ovulation in patients with POR by using the method of tonifying the kidney and regulating the weeks of ovulation. Methods 76 patients with POR were randomly divided into treatment group (n = 38) and control group (n = 38). The improvement of kidney yin deficiency syndrome, the dosage of gonadotropin Gnn and the level of estradiol E 2 on the day of HCG injection were compared between the two groups, and the fertilization rate of M 鈪,

本文編號(hào):1780756

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