本文選題：活血化瘀中藥復(fù)方 + 糖尿病周圍神經(jīng)病變��； 參考：《遼寧中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:系統(tǒng)的評價活血化瘀中藥復(fù)方治療糖尿病周圍神經(jīng)病變(diabetic peripheral neuropathy,DPN)的臨床療效。方法:系統(tǒng)檢索中、英文數(shù)據(jù)庫活血化瘀中藥復(fù)方治療DPN的隨機(jī)對照試驗(yàn)(RCT),英文文獻(xiàn)數(shù)據(jù)庫包括Pubmed、The Cochrane Library、Embase,中文文獻(xiàn)數(shù)據(jù)庫包括中國知網(wǎng)數(shù)據(jù)庫(CNKI)、萬方數(shù)據(jù)庫(Wanfang Data)、維普中文科技期刊數(shù)據(jù)庫、中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫(CBM)。通過兩人獨(dú)立篩選研究資料,并交叉所得研究資料,如遇分歧,則請教專業(yè)的統(tǒng)計學(xué)老師,本研究采用Cochrane提供的Review Manager 5.3軟件對本研究資料進(jìn)行統(tǒng)計學(xué)分析。結(jié)果:1.本研究共納入了14篇文獻(xiàn),合計1075例糖尿病周圍神經(jīng)病變患者。臨床有效率的Meta分析顯示納入各研究之間無明顯統(tǒng)計學(xué)差異(Chi2=5.45,P=0.96㧐0.1,I2=0%),兩組間臨床有效率具有顯著地統(tǒng)計學(xué)差異(P㩳0.00001)。2.在改善糖尿病周圍神經(jīng)病變患者的運(yùn)動神經(jīng)傳導(dǎo)速度(MCV)以及感覺神經(jīng)傳導(dǎo)速度(SCV)方面,兩組間的Meta分析結(jié)果均顯示P㩳0.00001。結(jié)論:活血化瘀中藥復(fù)方可有效改善糖尿病周圍神經(jīng)病變患者的臨床癥狀,提高運(yùn)動及感覺神經(jīng)傳導(dǎo)速度。
[Abstract]:Objective: to evaluate the clinical effect of traditional Chinese medicine for promoting blood circulation and removing blood stasis in the treatment of diabetic peripheral neuropathy (peripheral).Methods: in the system search,A randomized controlled trial of promoting blood circulation and removing blood stasis in the treatment of DPN was conducted. The English literature database included Pubmedus, the Cochrane Library Embase, the Chinese literature database including the Chinese knowledge Web database, the Wanfang data base, the Weipu Chinese science and technology periodical database.Chinese Biomedical Literature Database (CBM).The data of the study were screened independently by two people, and the data were crossed. If there were any differences, we should consult a professional statistics teacher. The data of this study were analyzed by Review Manager 5.3 software provided by Cochrane.The result is 1: 1.This study included 14 articles, a total of 1075 patients with diabetic peripheral neuropathy.Meta analysis showed that there was no significant difference between the two groups in the clinical efficacy. There was no significant statistical difference between the two groups in the clinical response rate of the two groups (P < 0.05). The clinical response rate of the two groups was significantly different (P < 0.05).In improving motor nerve conduction velocity (MCV) and sensory nerve conduction velocity (SCV) in patients with diabetic peripheral neuropathy, the results of Meta analysis between the two groups showed that P0. 0001.Conclusion: the prescription of promoting blood circulation and removing blood stasis can effectively improve the clinical symptoms of patients with diabetic peripheral neuropathy and improve the motor and sensory nerve conduction velocity.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R259;R277.7
，

本文編號：1736682