本文選題：心血管衰老　切入點：西北燥證　出處：《新疆醫(yī)科大學》2016年碩士論文

【摘要】：目的:探討烏魯木齊、伊犁兩地區(qū)漢族心血管衰老規(guī)律及與西北燥證的相關(guān)關(guān)系,為新疆地區(qū)心血管衰老的防治提供理論依據(jù)。方法:從烏魯木齊、伊犁兩地區(qū)共篩選474例自我評價健康的漢族居民,采用現(xiàn)場調(diào)查、實驗室檢測、心臟彩超檢查相結(jié)合的方法,比較烏魯木齊、伊犁兩地區(qū)漢族心血管衰老規(guī)律的差異,分析西北燥證與心血管衰老規(guī)律的相關(guān)關(guān)系。結(jié)果:(1)心血管衰老相關(guān)指標:1)血壓指標:SBP、PP、PPI;2)腎功能指標:BUN、Cr、Cys C、ALBU;3)心臟彩超指標:AD、LA、LVDd、LVDs、RA、RV、PA、LVEF。(2)烏魯木齊、伊犁兩地區(qū)漢族心血管衰老相關(guān)指標中SBP、PP、PPI、BUN、Cr、Cys C、AD、LA、LVDd、LVDs、RA、RV、PA指標均隨增齡逐漸上升,而ALBU、LVEF指標均隨增齡逐漸下降,其中可以作為心血管衰老標志物的指標有:SBP、PP、BUN、Cys C、ALBU、LA、LVDd、LVDs、RV、LVEF。(3)烏魯木齊、伊犁兩地區(qū)漢族西北燥證罹患率均隨增齡呈上升趨勢,烏魯木齊漢族西北燥證罹患率高于伊犁漢族(P0.05)。(4)相同年齡組,不同地區(qū)間比較:1)30-44歲組、45-59歲組:烏魯木齊漢族心血管衰老進展較伊犁漢族為快,在這兩個年齡組烏魯木齊漢族西北燥證罹患率亦較伊犁漢族為高,其中45-59歲組兩地區(qū)西北燥證罹患率比較差異有統(tǒng)計學意義(P0.05);2)60-74歲組:兩地區(qū)漢族心血管衰老均迅速進展,伊犁漢族心血管衰老進展較烏魯木齊漢族為快,該年齡組烏魯木齊漢族西北燥證罹患率較伊犁漢族略高,但伊犁漢族西北燥證罹患率上升幅度明顯大于烏魯木齊漢族,60-74歲組兩地區(qū)西北燥證罹患率比較差異無統(tǒng)計學意義(P0.05);3)≥75歲組:烏魯木齊漢族心血管衰老進展較伊犁漢族略快,但伊犁漢族西北燥證罹患率較烏魯木齊漢族略高,此年齡組兩地區(qū)西北燥證罹患率比較差異無統(tǒng)計學意義(P0.05)。(5)兩地區(qū)漢族西北燥證組SBP、PP、PPI、BUN、Cr、Cys-C、AD、LA、LVDd、LVDs、RA、RV、PA指標均較非西北燥證組高,同時ALBU、LVEF指標均較非西北燥證組為低,其中LA、LVDd、LVDs、RA、RV、PA、LVEF指標西北燥證組與非西北燥證組比較差異有統(tǒng)計學意義(P0.05)。結(jié)論:(1)隨著年齡增長,烏魯木齊、伊犁兩地區(qū)漢族心血管衰老進程并非恒速。(2)30-44歲組、45-59歲組兩地區(qū)漢族心血管衰老緩慢進展,烏魯木齊漢族心血管衰老進程較伊犁漢族為快,在這兩個年齡組烏魯木齊漢族西北燥證罹患率亦較伊犁漢族為高;在四個年齡組中,60-74歲組兩地區(qū)漢族心血管衰進程最快,該年齡段伊犁漢族心血管衰老進程較烏魯木齊漢族為快,此年齡組烏魯木齊漢族西北燥證罹患率較伊犁漢族為高,但伊犁漢族西北燥證罹患率上升幅度明顯大于烏魯木齊漢族;≥75歲組兩地區(qū)漢族心血管衰老進程緩慢,再次表現(xiàn)為烏魯木齊漢族心血管衰老進程較伊犁漢族略快,此年齡組伊犁漢族西北燥證罹患率較烏魯木齊漢族為高。(3)烏魯木齊、伊犁兩地區(qū)漢族心血管衰老進展與西北燥證存在相關(guān)關(guān)系,西北燥證是影響心血管衰老進程的主要加速因素之一。
[Abstract]:Objective: To investigate the relationship between Urumqi and Yili in two areas of cardiovascular aging laws of Han and Northwest Dryness Syndrome, and provide a theoretical basis for the prevention and treatment of cardiovascular aging in Xinjiang area. Methods: from Urumqi, Yili two areas were selected in 474 cases health self evaluation of Han residents, including field investigation, laboratory test methods, echocardiography the combination of comparative differences in Urumqi, Yili two areas Han cardiovascular aging laws, correlation analysis between Northwest Dryness Syndrome and cardiovascular aging law. Results: (1) related indicators of cardiovascular aging: 1) blood pressure index: SBP, PP, PPI; 2) renal function index: BUN, Cr, Cys, C, ALBU; 3) echocardiography indicators: AD, LA, LVDd, LVDs, RA, RV, PA, LVEF. (2) in Urumqi, Yili province two related indicators of cardiovascular aging in SBP, PP, PPI, BUN, Cr, Cys, C, AD, LA, LVDd, LVDs, RA, RV, PA indexes with age increased gradually, and A LBU, LVEF were decreased gradually with aging, which can be used as a marker of cardiovascular aging index: SBP, PP, BUN, Cys, C, ALBU, LA, LVDd, LVDs, RV, LVEF. (3) in Urumqi, Yili province two NDS rate increases with age increased Urumqi Han NDS was higher than that of Han nationality in Yili (P0.05). (4) the same age group, comparison between different regions: 1) 30-44 years old group, 45-59 years old group: progress in Urumqi Han Han Yili is cardiovascular aging fast, the attack rate is also high in the Yili in two age groups in Urumqi Han Xi North dryness, of which 45-59 years old group in two areas of Northwest Dryness Syndrome rate had significant difference (P0.05); 2) 60-74 groups: the two areas are Han cardiovascular aging rapidly, in Yili Han nationality and Han nationality in Urumqi with cardiovascular aging fast, the age group of Han nationality in Urumqi of Northwest Dryness Syndrome 緗規(guī)偅鐜囪緝浼婄妬姹夋棌鐣ラ珮,浣嗕紛鐘佹眽鏃忚タ鍖楃嚗璇佺焦鎮(zhèn)ｇ巼涓婂崌騫呭害鏄庢樉澶т簬涔岄瞾鏈ㄩ綈姹夋棌,60-74宀佺粍涓ゅ湴鍖鴻タ鍖楃嚗璇佺焦鎮(zhèn)ｇ巼姣旇緝宸紓鏃犵粺璁″鎰忎箟(P0.05);3)鈮，

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