本文選題：柏硝祛毒洗劑　切入點：肛裂　出處：《華北理工大學》2016年碩士論文

【摘要】：目的觀察柏硝祛毒洗劑熏洗用于肛裂術(shù)后的臨床表現(xiàn),通過比較患者術(shù)后疼痛、水腫、出血、創(chuàng)面愈合以及抑菌的評分差異,證實柏硝祛毒洗劑防治肛裂術(shù)后常見并發(fā)癥的臨床療效。方法選取符合標準的120例肛裂患者,隨機分為治療組(柏硝祛毒洗劑)和對照組(金玄痔科熏洗液),兩組患者術(shù)前以及術(shù)后常規(guī)治療一致,并對術(shù)前兩組的性別、病程、年齡以及術(shù)后的切口數(shù)目、術(shù)后當天的疼痛、水腫、出血的癥狀評分和術(shù)后當天創(chuàng)面的面積經(jīng)進行比較,判斷兩組是否具有可比性。肛裂術(shù)后,治療組以100ml柏硝祛毒洗劑兌900ml溫水熏洗,對照組予金玄痔科熏洗散兌1000ml溫水熏洗,55g/次,并控制兩組保持相同的熏洗時間與溫度。對術(shù)后的疼痛、水腫、出血進行癥狀量化評分,并分別記錄兩組術(shù)后用藥0、3、6、9d的癥狀評分以及創(chuàng)面愈合面積、創(chuàng)面愈合率以及創(chuàng)面愈合的時間;于術(shù)后用藥3、6、9d換藥時取患者創(chuàng)面少許分泌物進行抑菌實驗,測量抑菌環(huán)直徑,對抑菌環(huán)直徑進行評分,并記錄兩組患者治療后的總體療效和治療期間患者的不良反應,以統(tǒng)計學分析處理進行比較。結(jié)果兩組術(shù)前的性別、病程、年齡,以及術(shù)后的切口數(shù)目、術(shù)后當天的疼痛、水腫、出血的癥狀評分和術(shù)后當天創(chuàng)面的面積的比較,P0.05,差異無統(tǒng)計學意義,具有可比性。兩組術(shù)后用藥3、6、9d的疼痛、水腫、出血的評分以及創(chuàng)面愈合面積、創(chuàng)面愈合率較術(shù)后當天比較,P0.05,差異具有統(tǒng)計學意義;且治療組優(yōu)于照組,P0.05。兩組術(shù)后用藥3、6、9d的抑菌評分較術(shù)后當天比較,P0.05;且治療組優(yōu)于照組,P0.05。兩組術(shù)后創(chuàng)面愈合時間及術(shù)后用藥21d總療效比較,P0.05。治療期間,治療組10名患者見肛門瘙癢,對照組13名患者見肛門瘙癢,無特殊處理后癥狀好轉(zhuǎn),未對本次研究產(chǎn)生影響,兩組均未見其他不良反應。結(jié)論1柏硝祛毒洗劑熏洗用于肛裂術(shù)后,可明顯減輕術(shù)疼痛、水腫、出血癥狀,并能促進傷口愈合,縮短傷口愈合時間。2柏硝祛毒洗劑熏洗對肛裂術(shù)后傷口抑菌效果顯著,可防治傷口感染,安全有效,適宜臨床推廣。
[Abstract]:Objective to observe the clinical manifestations after anal fissure treated by fumigation and washing with antidoxide lotion, and to compare the scores of pain, edema, bleeding, wound healing and bacteriostasis after operation in patients with anal fissure. Methods 120 patients with anal fissure were selected. The two groups were randomly divided into two groups: the treatment group and the control group. The two groups had the same routine treatment before and after operation, and the gender, course of disease, age and the number of incisions after operation were the same in the two groups. The scores of pain, edema and bleeding on the day after operation were compared with the area of the wound on the day after operation. After anal fissure operation, the treatment group was fumigated with 100ml antitoxic lotion and 900ml warm water. The control group was treated with Jinxuan hemorrhoids fumigation powder and 1000ml warm water fumigation washing powder 55g / time, and the control group maintained the same fumigation time and temperature. The symptom scores, wound healing area, wound healing rate and wound healing time of the two groups were recorded respectively, and a little secretion of the wound was taken from the patients for bacteriostasis test, and the diameter of the bacteriostasis ring was measured. The diameter of the bacteriostasis ring was evaluated, and the overall curative effect and adverse reactions during the treatment were recorded. Results the sex, course, age of the two groups before operation were compared by statistical analysis. There was no significant difference in the number of incisions, pain, edema, bleeding symptom score and wound area on the day of operation (P 0.05). There was no significant difference between the two groups, and there was no significant difference between the two groups. The score of bleeding, the area of wound healing and the rate of wound healing were significantly higher than those on the day of operation (P 0.05). The bacteriostasis score of the two groups was better than that of the control group (P 0.05), and that of the treatment group was better than that of the irradiation group (P 0.05). The healing time of the wound and the total curative effect of 21 days after treatment were compared between the two groups during the treatment period. In the treatment group, 10 patients had anal itching, while in the control group, 13 patients had anal itching. Conclusion 1 fumigation and washing with antidotal lotion for anal fissure can significantly relieve pain, edema, bleeding symptoms and promote wound healing after anal fissure. The time of wound healing was shortened. 2. Fumigation and washing with Bahnite dispel toxin lotion had obvious effect on bacteriostasis after anal fissure operation. It could prevent and cure wound infection, and was safe and effective. It was suitable for clinical application.
【學位授予單位】：華北理工大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R266

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