補(bǔ)腎滋血湯治療月經(jīng)過(guò)少腎虛證的臨床研究
發(fā)布時(shí)間:2018-03-26 05:32
本文選題:月經(jīng)過(guò)少 切入點(diǎn):腎虛證 出處:《廣西中醫(yī)藥大學(xué)》2016年碩士論文
【摘要】:目的:觀察補(bǔ)腎滋血湯對(duì)月經(jīng)過(guò)少患者經(jīng)量的影響,研究補(bǔ)腎滋血湯治療月經(jīng)過(guò)少的臨床效果。方法:本研究病例來(lái)自2014年1月至2015年12月期間,在廣西中醫(yī)藥大學(xué)附屬瑞康醫(yī)院婦科門(mén)診就診的60例患者。符合月經(jīng)過(guò)少腎虛證的診斷、辯證標(biāo)準(zhǔn)。病例隨機(jī)分為觀察組和對(duì)照組各30例。觀察組給予補(bǔ)腎滋血湯,每日1付,水煎后分2次內(nèi)服;對(duì)照組給予烏雞白鳳丸,每次1丸,1日2次溫水送服,兩組治療3個(gè)月經(jīng)周期后,隨訪3個(gè)月。觀察患者月經(jīng)量、色、質(zhì)及行經(jīng)時(shí)間的改善情況,以及臨床癥狀、子宮內(nèi)膜厚度、性激素、基礎(chǔ)體溫的改善情況,觀察結(jié)果經(jīng)spss20.0統(tǒng)計(jì)學(xué)軟件分析后,判定兩組藥物的有效性和安全性。結(jié)果:1.兩組對(duì)患者經(jīng)量的影響:觀察組治療前后經(jīng)量評(píng)分由20.60±6.19分上升至50.20±11.60分,對(duì)照組治療前后經(jīng)量評(píng)分由20.90±6.01分上升至42.87±13.49分,兩組治療前后比較,差異有統(tǒng)計(jì)學(xué)意義(p0.01),治療后兩組經(jīng)量均有所增加。治療后兩組經(jīng)量評(píng)分差值比較,差異有統(tǒng)計(jì)學(xué)意義(p0.05),觀察組療效優(yōu)于對(duì)照組。兩組治療后隨訪經(jīng)量改善的療效比較,觀察組治愈率為16.67%,顯效率為46.67%,有效率為23.33%,總有效率為86.67%;對(duì)照組治愈率為3.33%,顯效率為36.67%,有效率為30.00%,總有效率為70.00%,治療后兩組間比較,差異有統(tǒng)計(jì)學(xué)意義(p0.05),觀察組療效優(yōu)于對(duì)照組。2.兩組癥狀的改善情況:觀察組治療前后癥狀總積分由19.60±5.42下降至5.73±4.66,對(duì)照組治療前后癥狀總積分由18.20±5.88下降至7.73±5.87,兩組治療前后比較,差異有統(tǒng)計(jì)學(xué)意義(p0.01)。治療后兩組癥狀總積分差值比較,差異有統(tǒng)計(jì)學(xué)意義(p0.01),觀察組療效優(yōu)于對(duì)照組。3.兩組對(duì)性激素、子宮內(nèi)膜、基礎(chǔ)體溫的影響:兩組改善子宮內(nèi)膜厚度比較,差異均有統(tǒng)計(jì)學(xué)意義(p0.01),兩組均可明顯促進(jìn)黃體中期的子宮內(nèi)膜增生和修復(fù)。治療后兩組間比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(p0.05),兩組藥物對(duì)黃體中期子宮內(nèi)膜厚度的改善情況無(wú)明顯差異。兩組改善性激素情況比較,補(bǔ)腎滋血湯可輕微升高血清早卵泡期的FSH值和E值(p0.05)。對(duì)T、PRL、LH值均沒(méi)有明顯影響(p0.05)。烏雞白鳳丸對(duì)FSH、E、T、PRL、LH值均沒(méi)有明顯影響(p0.05)。兩組藥物對(duì)治療前后BBT的改善情況均無(wú)明顯影響(p0.05)。4.兩組綜合療效比較:觀察組治愈率為16.67%,顯效率為33.33%,有效率為40.00%,總有效率為90.00%;對(duì)照組治愈率為3.34%,顯效率為23.33%,有效率為50.00%,總有效率為76.67%,治療后兩組間比較,差異有統(tǒng)計(jì)學(xué)意義(p0.05),觀察組療效優(yōu)于對(duì)照組。結(jié)論:補(bǔ)腎滋血湯治療月經(jīng)過(guò)少具有良好臨床療效。
[Abstract]:Objective: to observe the effect of Bushen Zixue decoction on menstrual insufficiency, and to study the clinical effect of Bushen Zixue decoction on menorrhagia. Methods: this study was conducted from January 2014 to December 2015. Sixty patients in the gynecological clinic of Ruikang Hospital affiliated to Guangxi University of traditional Chinese Medicine. According to the diagnosis and dialectical standard of deficiency of menstruation and kidney syndrome, the cases were randomly divided into observation group and control group, 30 cases each. The observation group was given Bushen Zixue decoction, 1 payment per day. The control group was given Wuji Baifeng pills (1 pill each time, 2 times a day with warm water). After 3 menstrual cycles, the two groups were followed up for 3 months. The improvement of menstrual volume, color, quality and menstrual time were observed. And the improvement of clinical symptoms, endometrial thickness, sex hormone and basic body temperature. The results were analyzed by spss20.0 statistical software. Results the effect of the two groups on the patients' dosages was determined. Results: before and after treatment, the menstrual volume score of the observation group increased from 20.60 鹵6.19 to 50.20 鹵11.60, and that of the control group increased from 20.90 鹵6.01 to 42.87 鹵13.49, and that of the control group increased from 20.90 鹵6.01 to 42.87 鹵13.49, and that of the control group increased from 20.90 鹵6.01 to 42.87 鹵13.49 before and after treatment. The difference between the two groups before and after treatment was statistically significant (p 0.01), and the volume of the two groups increased after treatment. The difference was statistically significant (P 0.05). The curative effect of the observation group was better than that of the control group. In the observation group, the cure rate was 16.67, the markedly effective rate was 46.67, the effective rate was 23.33 and the total effective rate was 86.67; in the control group, the cure rate was 3.33; the markedly effective rate was 36.67; the effective rate was 30.007; and the total effective rate was 70.00.After the treatment, the two groups were compared. The effect of observation group was better than that of control group. The symptom score of observation group decreased from 19.60 鹵5.42 to 5.73 鹵4.66 before and after treatment, and that of control group decreased from 18.20 鹵5.88 to 7.73 鹵5.87 before and after treatment. The difference was statistically significant (P 0.01). After treatment, the difference in the total score of symptoms between the two groups was statistically significant. The curative effect of the observation group was better than that of the control group .3.The effect of the two groups on sex hormone, endometrium and basic body temperature: the two groups improved the thickness of endometrium. The difference was statistically significant (P 0.01). Both groups could significantly promote endometrial hyperplasia and repair in the middle luteal phase. There was no significant difference in endometrial thickness between the two groups, and there was no significant difference between the two groups in improving the endometrial thickness in the middle luteal phase. Bushen Zixue decoction can slightly increase the FSH value and E value of serum early follicle phase (P 0.05). There is no significant effect on the serum FSH value and E value of Bushen Zixue decoction. There is no significant effect of Wuji Baifeng Pill on BBT before and after treatment. There is no significant effect of Wuji Baifeng Pill on BBT before and after treatment. Comparison between the two groups: the cure rate in the observation group was 16.67, the effective rate was 33.33, the effective rate was 40.003, the total effective rate was 90.00.The cure rate in the control group was 3.34, the effective rate was 23.33, the effective rate was 50.00,the total effective rate was 76.677.After the treatment, the two groups were compared. The difference was statistically significant (P 0.05). The curative effect of the observation group was better than that of the control group. Conclusion: Bushen Zixue decoction has good clinical effect in treating menorrhagia.
【學(xué)位授予單位】:廣西中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類(lèi)號(hào)】:R271.111
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