本文選題：肺間質(zhì)纖維化　切入點(diǎn)：分期　出處：《山東中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:探討肺間質(zhì)纖維化(PF)患者的中醫(yī)體質(zhì)分布規(guī)律,有助于PF患者的早期診斷,并為PF患者提供個(gè)體化治療方案。方法:通過搜集2013年9月到2016年1月入住山東省中醫(yī)院的138例肺間質(zhì)纖維化患者,并根據(jù)臨床癥狀、肺功能、HRCT表現(xiàn)分為三期。采用問卷及電話回訪的方式對(duì)患者的基本情況和中醫(yī)體質(zhì)進(jìn)行調(diào)查。統(tǒng)計(jì)不同的體質(zhì)類型在肺間質(zhì)纖維化患者三期中的分布情況,將調(diào)查得到的數(shù)據(jù)建立數(shù)據(jù)庫(kù)利用單因素方差分析和卡方檢驗(yàn)分析得出體質(zhì)類型與肺間質(zhì)纖維化患者病情程度的相關(guān)性。結(jié)果:1.138例肺間質(zhì)纖維化患者中男女患者比例為2:1。2.138例肺間質(zhì)纖維化患者的主要體質(zhì)類型是氣虛質(zhì)、血瘀質(zhì),所占比例分別為21.01%和18.84%,其次為痰濕質(zhì)和陰虛質(zhì),所占比例分別為16.67%和14.49%。3.肺間質(zhì)纖維化早期患者中痰濕質(zhì)所占比例最大,為32.14%,其次為濕熱質(zhì)和血瘀質(zhì),分別為25%和17.86%。慢性遷延期患者中氣虛質(zhì)所占比例最大,為30%,其次為血瘀質(zhì)和痰濕質(zhì),分別為21.43%和15.71%。晚期患者中陰虛質(zhì)(30%)、陽(yáng)虛質(zhì)(20%)所占比例較大,其次為氣虛質(zhì)(17.5%)、血瘀質(zhì)(15%)。結(jié)論:1.肺間質(zhì)纖維化患者在性別上,男性多于女性。2.肺間質(zhì)纖維化患者體質(zhì)類型主要是氣虛質(zhì)、血瘀質(zhì);早期以痰濕質(zhì)為主,慢性遷延期以氣虛質(zhì)為主,晚期以陰虛質(zhì)為主。3.肺間質(zhì)纖維化患者的嚴(yán)重程度和中醫(yī)體質(zhì)相關(guān)。
[Abstract]:Objective: to investigate the distribution of TCM constitution in patients with pulmonary interstitial fibrosis (PF), and to help the early diagnosis of PF patients. Methods: 138 patients with pulmonary interstitial fibrosis admitted to Shandong traditional Chinese Medicine Hospital from September 2013 to January 2016 were collected, and according to the clinical symptoms, HRCT findings of pulmonary function were divided into three stages. The basic status of patients and TCM physique were investigated by questionnaire and telephone interview. The distribution of different physique types in three stages of pulmonary interstitial fibrosis was analyzed. The data obtained from the investigation were established in a database. The relationship between the physical types and the severity of pulmonary interstitial fibrosis was obtained by univariate ANOVA and chi-square test. Results among 1.138 patients with pulmonary interstitial fibrosis, male and female were involved in the study. The main physical type of 2: 1.2.138 patients with pulmonary interstitial fibrosis was qi deficiency. The proportion of blood stasis was 21.01% and 18.84% respectively, followed by phlegm dampness and yin deficiency, accounting for 16.67% and 14.49.3.The proportion of phlegm dampness was the largest in the early stage of pulmonary interstitial fibrosis (32.14), followed by dampness and blood stasis. The proportion of qi deficiency was 30, followed by blood stasis and phlegm dampness, which were 21.43% and 15.71%, respectively. Secondly, Qi deficiency is 17.5m and blood stasis is 150.Conclusion 1. In the patients with pulmonary interstitial fibrosis, male is more than female in sex. The physique types of pulmonary interstitial fibrosis are mainly qi deficiency and blood stasis, and phlegm and dampness are the main types in the early stage. The chronic prolongation period was mainly qi deficiency and the late stage was yin deficiency. 3. The severity of pulmonary interstitial fibrosis was related to the constitution of traditional Chinese medicine.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

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