本文選題：原發(fā)性血小板增多癥　切入點(diǎn)：證素　出處：《南京中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：統(tǒng)計(jì)分析臨床原發(fā)性血小板增多癥(essential thrombocythemia, ET)患者的證候,進(jìn)行證素評分,探討各證素的分布特點(diǎn),以期為ET的中醫(yī)辨證論治提供新的思路和方法。方法：對84例明確診斷ET且符合納入標(biāo)準(zhǔn)的患者進(jìn)行相關(guān)證候采集,然后應(yīng)用證素積分方法,統(tǒng)計(jì)分析出ET相關(guān)主要證素,并從性別、年齡、危險(xiǎn)分層等角度進(jìn)行差異性比較。結(jié)果：根據(jù)ET主要證素積分的統(tǒng)計(jì)和分析,概述如下：1.ET的主要證素分布情況：病位以肝為主要證素,脾、腎次之,累及經(jīng)絡(luò)、心神等；病性證素：陰虛、血瘀、氣虛、氣滯的證素積分最高,血虛、陽亢、陽虛次之,涉及寒、濕、熱等。此外,未絕經(jīng)的女性患者,胞宮在病位證素中有重要意義。2.從性別角度進(jìn)行證素比較：男、女組進(jìn)行病位證素比較未見明顯差異；病性證素分析顯示,女性患者血瘀征象較男性患者明顯,且機(jī)體更容易受寒、濕的影響。3.從各年齡段分析：各年齡段主要病位證素都為肝,且無明顯差異；中、老年患者其脾、腎二臟功能失調(diào)較年輕患者明顯,累及心神、經(jīng)絡(luò)出現(xiàn)相關(guān)癥狀更明顯。從病性看,高年齡段更陽虛、氣虛、血虛更明顯,低年齡段氣滯、陽亢、陰虛更明顯。4.高危、低危組證素積分比較結(jié)果示：高危組ET患者病位累及脾、腎、心神、經(jīng)絡(luò)較低危組更明顯,氣滯、血瘀、氣虛、陽虛、血虛等相關(guān)征象也較低危組明顯；而陽亢、陰虛相關(guān)表現(xiàn)多在低危組出現(xiàn)。結(jié)論：ET病位主要在肝,累及脾、腎,對心神、經(jīng)絡(luò)、胞宮(女性)的結(jié)構(gòu)和功能有較大影響：ET的病因病機(jī)多為虛實(shí)夾雜,以氣虛、陰虛為本虛,氣滯、血瘀為標(biāo)實(shí),久病兼夾陽虛、血虛表現(xiàn)。女性患者瘀象較男性明顯；高危及老年患者虛損征象明顯,臨床在活血化瘀祛邪的同時更應(yīng)重視扶正固本。
[Abstract]:Objective: to analyze the syndromes of patients with essential thrombocytopenia (et), to evaluate the syndromes, and to explore the distribution characteristics of the syndromes in patients with essential thrombocytopenia (et). Methods: 84 patients with et who met the inclusion criteria were collected with relevant syndromes, and then the main syndromes of et were statistically analyzed by using the integral method of syndromes. Results: according to the statistics and analysis of et's main syndromes, the distribution of et's main syndromes was summarized as follows: liver was the main syndromes, spleen and kidney were the second. Involving the meridians, the heart and the mind, the factors of disease syndrome: yin deficiency, blood stasis, qi deficiency, qi stagnation, the highest score of syndromes, blood deficiency, hyperactivity of yang, yang deficiency, and so on. In addition, women with unmenopausal women are involved in cold, dampness, heat, etc. There was no significant difference between male and female in the comparison of syndromes from the gender point of view, and the analysis of the factors of disease syndrome showed that the blood stasis sign of female patients was more obvious than that of male patients. And the body is more susceptible to cold and dampness. 3. Analysis from different ages: the main syndromes of all age groups are liver, and there is no significant difference; in middle and old patients, the dysfunction of spleen, kidney and viscera is more obvious than that of young patients, involving heart and mind. The symptoms related to meridians were more obvious. From the point of view of disease, the high age group had more yang deficiency, qi deficiency, blood deficiency more obvious, lower age group qi stagnation, yang hyperactivity, yin deficiency more obvious .4. high risk, The results showed that the disease position of et patients in high risk group involved spleen, kidney, heart and spirit, meridian and meridian were more obvious than those in low risk group, Qi stagnation, blood stasis, qi deficiency, yang deficiency, blood deficiency and other related signs were more obvious than those in low risk group, while hyperactivity of yang was more obvious than that of low risk group. Conclusions the disease position of 1: et is mainly in liver, spleen, kidney, the structure and function of heart and spirit, meridian and phratry (female). The etiology and pathogenesis of et is mostly composed of deficiency of qi and deficiency of yin, which is based on deficiency of qi and deficiency of yin, and it is mainly caused by deficiency of qi, deficiency of yin, deficiency of yin and deficiency of yin, which has great influence on the structure and function of the meridians and meridians. Qi stagnation, blood stasis as the standard solid, long illness and Yang deficiency, blood deficiency performance. Female patients with blood stasis is more obvious than men, high risk and elderly patients with deficiency signs are obvious, the clinical practice in promoting blood circulation to remove blood stasis and evil should pay more attention to strengthening and strengthening the root at the same time.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R259

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 朱文鋒;黃碧群;陳新宇;;病性證素辨別的意義與方法[J];中醫(yī)藥學(xué)刊;2006年02期

2 匡艷紅;朱文鋒;黃碧群;王榮田;匡艷芳;;方劑主治證的證素分析[J];湖南中醫(yī)藥大學(xué)學(xué)報(bào);2008年06期

3 戴芳;唐亞平;周艷;王飛;龔超奇;朱文鋒;;裂紋舌與病性證素相關(guān)性的研究[J];遼寧中醫(yī)雜志;2010年11期

4 戴芳;唐亞平;周艷;王飛;龔超奇;朱文鋒;;黃苔與病性證素關(guān)系的研究[J];時珍國醫(yī)國藥;2011年09期

5 黃碧群,朱鎮(zhèn)華;“證素”及其與相關(guān)概念的關(guān)系[J];中醫(yī)研究;2005年06期

6 朱文鋒;;構(gòu)建“證素辨證”新體系的意義[J];浙江中醫(yī)藥大學(xué)學(xué)報(bào);2006年02期

7 楊東寧;;腦梗死分期與中醫(yī)病性證素的關(guān)系[J];光明中醫(yī);2011年10期

8 王勇;謝世平;梁潤英;郭選賢;李丹;施淼;薛敏;郭曉輝;;基于文獻(xiàn)的艾滋病病性證素分布規(guī)律研究[J];遼寧中醫(yī)雜志;2011年11期

9 朱文鋒,甘慧娟;證素內(nèi)容的辨析[J];中醫(yī)藥導(dǎo)報(bào);2005年01期

10 黃浩;唐亞平;戴芳;龔超奇;周艷;王飛;朱文鋒;;紫舌與病性證素相關(guān)性的研究[J];時珍國醫(yī)國藥;2013年07期

相關(guān)會議論文 前3條

1 吳同玉;楊雪梅;李燦東;林端宜;;血糖與濕病性證素的相關(guān)分析[A];中華中醫(yī)藥學(xué)會中醫(yī)診斷學(xué)分會2007’年會論文集[C];2007年

2 黃碧群;;中醫(yī)辨證實(shí)訓(xùn)教學(xué)改革方案[A];中華中醫(yī)藥學(xué)會中醫(yī)診斷學(xué)分會第十次學(xué)術(shù)研討會論文集[C];2009年

3 姜亞軍;;腦梗死患者血小板-單核細(xì)胞聚集物水平與中風(fēng)病性證素的關(guān)系研究[A];2010中國醫(yī)師協(xié)會中西醫(yī)結(jié)合醫(yī)師大會摘要集[C];2010年

相關(guān)重要報(bào)紙文章 前3條

1 朱文鋒 黃碧群 陳新宇;病性證素辨別的意義與方法[N];中國中醫(yī)藥報(bào);2006年

2 朱文鋒 張華敏;證素的八項(xiàng)基本特征[N];中國中醫(yī)藥報(bào);2006年

3 黃碧群 朱曉華 朱文鋒;證素概念的辨析[N];中國中醫(yī)藥報(bào);2006年

相關(guān)碩士學(xué)位論文 前9條

1 孫玉琴;小兒咳嗽變異性哮喘中醫(yī)證素與環(huán)境因素相關(guān)性研究[D];云南中醫(yī)學(xué)院;2016年

2 黃燕;原發(fā)性血小板增多癥的中醫(yī)證素初探[D];南京中醫(yī)藥大學(xué);2016年

3 蔡秋芳;腦梗死患者血小板—單核細(xì)胞聚集物水平與中風(fēng)病性證素的關(guān)系研究[D];南京中醫(yī)藥大學(xué);2008年

4 韓惠慧;短暫性腦缺血發(fā)作分型與中醫(yī)證侯的相關(guān)性研究[D];河北醫(yī)科大學(xué);2011年

5 楊禾欣;進(jìn)行性肌營養(yǎng)不良癥分型病情分級及實(shí)驗(yàn)室指標(biāo)與中醫(yī)證候的相關(guān)性研究[D];河北醫(yī)科大學(xué);2008年

6 馮婉枝;慢性淋巴細(xì)胞性甲狀腺炎中醫(yī)證素及與客觀指標(biāo)相關(guān)性分析[D];廣州中醫(yī)藥大學(xué);2014年

7 王岫崢;后循環(huán)梗死分期分型與中醫(yī)主證關(guān)系的研究[D];河北醫(yī)科大學(xué);2010年

8 劉娟娟;基于現(xiàn)代名老中醫(yī)經(jīng)驗(yàn)的喘病辨證與方藥規(guī)律的初步研究[D];河南中醫(yī)學(xué)院;2014年

9 官涵;子宮肌瘤中醫(yī)證素特點(diǎn)研究[D];福建中醫(yī)藥大學(xué);2014年

，

本文編號：1660398