本文選題：枇杷清肺飲加減　切入點(diǎn)：生物敷料　出處：《南京中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：觀察枇杷清肺飲加減方聯(lián)合靚芙康復(fù)貼敷料治療輕中度尋常痤瘡的臨床療效和安全性。方法：將90例中醫(yī)辨證為肺經(jīng)風(fēng)熱證的尋常痤瘡患者,隨機(jī)分三組：A組、B組及C組各30例,其中C組1例失訪,最后89例患者進(jìn)入統(tǒng)計(jì)分析。A組采用枇杷清肺飲加減聯(lián)合靚芙康復(fù)貼敷料進(jìn)行治療；B組,單用枇杷清肺飲加減進(jìn)行治療；C組單用靚芙康復(fù)貼敷料進(jìn)行治療；治療4周后進(jìn)行療效判定。治療前后根據(jù)總皮損數(shù)目的變化作臨床療效評(píng)價(jià)；根據(jù)中醫(yī)證候積分變化情況進(jìn)行中醫(yī)證候的療效評(píng)價(jià)；根據(jù)皮膚臨床狀況總積分變化情況作皮膚臨床改善情況的評(píng)價(jià)。根據(jù)安全性指標(biāo)變化情況做安全性評(píng)價(jià)。結(jié)果：經(jīng)4周治療后,三組患者總皮損數(shù)均較治療前下降,治療前后差異均有統(tǒng)計(jì)學(xué)意義(P0.05),相較于C組, A、B兩組的下降幅度更大。治療結(jié)束后A組的總有效率為80.00%,B組總有效率為50.00%,C組總有效率為20.69%,三組臨床療效比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。三組治療后肺經(jīng)風(fēng)熱證的癥狀及體征均較治療前改善,與之相應(yīng)的中醫(yī)證候總積分與治療前相比也均有顯著性差異(P0.05),治療結(jié)束后A組、B組及C組中醫(yī)證候療效的總有效率分別為76.67%、70%和17.24%,A、B兩組比較中醫(yī)證候療效無顯著性差異(P0.05),且均顯著優(yōu)于C組(P0.05)。在改善皮膚臨床情況方面,治療中采用靚芙康復(fù)貼敷料的A組與C組,治療后兩組患者皮膚臨床情況總積分均較治療前顯著下降(P0.05),而B組患者治療前后無顯著性差異(P0.05)。治療結(jié)束后三組患者均未出現(xiàn)嚴(yán)重不良反應(yīng),A組3例與B組2例,服中藥后出現(xiàn)輕度胃部不適,調(diào)整服藥時(shí)間及服藥方法后,不適癥狀消失。治療前后各項(xiàng)指標(biāo)均在正常參考值范圍之內(nèi)。結(jié)論：枇杷清肺飲加減聯(lián)合靚芙康復(fù)貼敷料治療輕中度尋常痤瘡,安全有效,可以作為治療輕中度尋常痤瘡臨床選擇,為其治療提供了新思路；聯(lián)合治療組在治療的同時(shí),對(duì)患者的皮膚情況起到改善作用,可以增加患者的舒適度及滿意度,提高患者的依從性。
[Abstract]:Objective: to observe the clinical efficacy and safety of loquat Qingfei decoction combined with Liangfukangtan dressing in the treatment of mild to moderate acne vulgaris. Methods: 90 cases of acne vulgaris with syndrome differentiation of lung meridian and wind heat were treated with traditional Chinese medicine. They were randomly divided into three groups: 30 cases in group A, 30 cases in group B and 30 cases in group C. among them, one case in group C was lost, and 89 cases in group A were treated with loquat Qingfei Yin plus subtraction plus Fuliangfu plaster dressing, and group B was treated by adding and subtracting loquat Qingfei Yin with Fuliangfu plaster. The treatment group C was treated with Liangfu rehabilitation plaster alone, the curative effect was judged after 4 weeks of treatment, and the clinical curative effect was evaluated according to the changes of the total number of skin lesions before and after treatment. To evaluate the curative effect of TCM syndrome according to the change of TCM syndromes integral; The clinical improvement of skin was evaluated according to the total integral change of skin clinical condition and the safety evaluation was made according to the change of safety index. Results: after 4 weeks of treatment, the total number of skin lesions in the three groups was lower than that before treatment. The difference before and after treatment was statistically significant (P 0.05). Compared with group C, the decrease of Agna B group was greater. After the treatment, the total effective rate of group A was 80.00cm. The total effective rate of group B was 50.00cm. The total effective rate of group C was 20.69. There was a difference among the three groups in clinical efficacy. After treatment, the symptoms and signs of lung meridian heat syndrome in the three groups were improved compared with those before treatment. There were significant differences in the total integral of TCM syndromes compared with those before treatment. After the treatment, the total effective rates of TCM syndromes in group A and group C were 76.67% and 17.24% respectively. There was no significant difference between group A and group C in TCM syndromes. The difference of P0.05 was significantly better than that of group C in improving the clinical condition of skin. Group A and group C were treated with Liangfu rehabilitation dressing. After treatment, the total clinical score of skin in both groups was significantly lower than that before and after treatment, but there was no significant difference between group B and group B. after the treatment, there were no serious adverse reactions in group A (3 cases) and group B (2 cases). After taking traditional Chinese medicine, there is mild stomach discomfort, after adjusting the time and method of taking medicine, All indexes were within the normal reference value before and after treatment. Conclusion: it is safe and effective to treat mild to moderate acne vulgaris by adding and subtracting loquat Qingfei Yin and Liangfu Kangfeng paste dressing. It can be used as a clinical choice for the treatment of mild to moderate acne vulgaris, and provides a new idea for the treatment of acne vulgaris. The combined treatment group can improve the skin condition of the patients and increase the comfort and satisfaction of the patients. Improve compliance of patients.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R275.9

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 王召昆;;枇杷清肺飲加減治療痤瘡28例療效觀察[J];云南中醫(yī)中藥雜志;2006年06期

2 劉興亞;劉丹妮;;枇杷清肺飲加味治療痤瘡82例[J];吉林中醫(yī)藥;2007年04期

3 衷學(xué)軍;肖延華;楊紅衛(wèi);曾偉剛;肖鳳儀;焦敏;肖群益;;枇杷清肺飲合小柴胡湯治療痤瘡78例[J];四川中醫(yī);2009年07期

4 王光亞;陳詠梅;;枇杷清肺飲加味治療座瘡82例[J];中國現(xiàn)代藥物應(yīng)用;2009年21期

5 陳中偉;;枇杷清肺飲加味治療痤瘡65例臨床觀察[J];中醫(yī)藥導(dǎo)報(bào);2010年05期

6 馬友;;枇杷清肺飲治療痤瘡120例[J];中國民間療法;2010年07期

7 翟軍俊;;加減枇杷清肺飲治療痤瘡[J];中國民族民間醫(yī)藥;2010年23期

8 馬天龍;;枇杷清肺飲加減治療粉刺84例療效顯著[J];內(nèi)蒙古中醫(yī)藥;2013年23期

9 許光倉;孔瑞龍;;枇杷清肺飲治療痤瘡療效觀察[J];實(shí)用中醫(yī)藥雜志;2013年07期

10 孫剛;;中藥枇杷清肺飲治痤瘡96例[J];中國社區(qū)醫(yī)師;1989年01期

相關(guān)會(huì)議論文 前3條

1 王思農(nóng);;枇杷清肺飲加減治療20例尋常痤瘡療效觀察[A];中華中醫(yī)藥學(xué)會(huì)皮膚科分會(huì)第七次學(xué)術(shù)年會(huì)、2010年重慶四川中西醫(yī)結(jié)合皮膚性病學(xué)術(shù)年會(huì)、全國中西醫(yī)結(jié)合診療皮膚性病新進(jìn)展新技術(shù)學(xué)習(xí)班論文匯編[C];2010年

2 陳元慶;趙桂琴;林順姬;;五花枇杷清肺飲治療痤瘡90例的觀察[A];2003中國中西醫(yī)結(jié)合皮膚性病學(xué)術(shù)會(huì)議論文匯編[C];2003年

3 譚笑;;中醫(yī)如何治療粉刺[A];首屆中國中醫(yī)藥美容學(xué)術(shù)交流大會(huì)論文匯編[C];2004年

相關(guān)重要報(bào)紙文章 前1條

1 李萍;中醫(yī)打贏“粉刺”戰(zhàn)[N];保健時(shí)報(bào);2004年

相關(guān)碩士學(xué)位論文 前10條

1 滕超;枇杷清肺飲治療尋常痤瘡系統(tǒng)評(píng)價(jià)及肺經(jīng)風(fēng)熱證臨床觀察[D];云南中醫(yī)學(xué)院;2016年

2 胡君;枇杷清肺飲加減聯(lián)合靚芙康復(fù)貼敷料治療輕中度尋常痤瘡的臨床療效觀察[D];南京中醫(yī)藥大學(xué);2016年

3 劉立;枇杷清肺飲加減治療新加坡中國兩地尋常性痤瘡的臨床觀察[D];南京中醫(yī)藥大學(xué);2009年

4 姜正斌;痤瘡的發(fā)病情況探討及枇杷清肺飲加減治療尋常痤瘡的臨床觀察[D];南京中醫(yī)藥大學(xué);2010年

5 王帥;枇杷清肺飲對(duì)女性尋常性痤瘡患者血清雄激素（主要是睪酮）水平的影響[D];浙江中醫(yī)藥大學(xué);2013年

6 周軼;果酸聯(lián)合枇杷清肺飲加減方治療尋常型痤瘡的臨床療效觀察[D];南京中醫(yī)藥大學(xué);2010年

7 熊潔勤;枇杷清肺飲加減治療尋常性痤瘡的臨床研究[D];南京中醫(yī)藥大學(xué);2006年

8 王洋洋;枇杷清肺飲聯(lián)合火針治療尋常痤瘡的臨床觀察[D];黑龍江中醫(yī)藥大學(xué);2015年

9 解杰;枇杷清肺飲加減內(nèi)服配合交泰丸填臍療法治療肺胃血熱證青年痤瘡臨床研究[D];山東中醫(yī)藥大學(xué);2010年

10 陳鋮;針刺結(jié)合枇杷清肺飲治療肺經(jīng)風(fēng)熱型尋常痤瘡的臨床觀察[D];湖北中醫(yī)藥大學(xué);2013年

，

本文編號(hào)：1659659