本文選題：消化性潰瘍　切入點(diǎn)：肝胃郁熱　出處：《長春中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:通過觀察抑瘍顆粒治療消化性潰瘍(肝胃郁熱型)的臨床療效,以證明本方能明顯改善患者的臨床癥狀,對(duì)提高消化性潰瘍(肝胃郁熱型)的治療水平具有積極意義。方法:本研究取符合消化性潰瘍(肝胃郁熱型)診斷標(biāo)準(zhǔn)的患者72例,隨機(jī)分為治療組和對(duì)照組各36例。其中治療組:給予由長春中醫(yī)藥大學(xué)附屬醫(yī)院免煎藥房提供的抑瘍顆粒,1付溫水沖服300ml,150ml日2次早晚口服;對(duì)照組:給予由大連泛美藥業(yè)有限公司(批準(zhǔn)文號(hào):國藥準(zhǔn)字Z10970079)生產(chǎn)的潰得康顆粒,10g/次,2次/日口服。兩組療程均為28天。經(jīng)統(tǒng)計(jì)學(xué)分析,以中醫(yī)癥候評(píng)定標(biāo)準(zhǔn)和胃鏡作為評(píng)價(jià)指標(biāo)進(jìn)行評(píng)定。結(jié)果:1、本研究實(shí)際入組72例,脫落及剔除病例均為0例,兩組患者依從性良好。2、療效分析治療28天后,兩組治療后癥狀總積分比較,經(jīng)統(tǒng)計(jì)學(xué)處理,P0.01,有統(tǒng)計(jì)學(xué)意義。治療后次要癥狀比較,在改善喜冷飲、嘈雜、便秘等癥狀方面,經(jīng)統(tǒng)計(jì)學(xué)處理,P0.05,無統(tǒng)計(jì)學(xué)意義。在改善吞酸、情緒抑郁或煩躁易怒癥狀方面,治療組優(yōu)于對(duì)照組,經(jīng)統(tǒng)計(jì)學(xué)處理,P0.05,有統(tǒng)計(jì)學(xué)意義。治療后兩組中醫(yī)證候療效比較,治療組的中醫(yī)證候療效優(yōu)于對(duì)照組,經(jīng)統(tǒng)計(jì)學(xué)處理,P0.05,有統(tǒng)計(jì)學(xué)意義。治療后兩組胃鏡療效比較,經(jīng)統(tǒng)計(jì)學(xué)處理,P0.05,無統(tǒng)計(jì)學(xué)意義。3、兩組患者在服藥期間均未發(fā)生不良反應(yīng)事件。結(jié)論:抑瘍顆粒治療組可以有效地治療消化性潰瘍(肝胃郁熱型),臨床療效優(yōu)于潰得康顆粒,兩組藥物均能有效地改善中醫(yī)證候。但抑瘍顆�？梢愿纳莆鸽涮弁�、口干口苦、胃脘部灼熱、吞酸、情緒抑郁或煩躁易怒等癥狀,值得臨床進(jìn)一步研究。
[Abstract]:Objective: to observe the clinical effect of Yaoyang granule in the treatment of peptic ulcer (liver-stomach stagnation and heat type), so as to prove that the prescription can obviously improve the clinical symptoms of the patients. Methods: 72 cases of peptic ulcer (hepatogastric stagnation and heat type) who met the diagnostic criteria of peptic ulcer (liver-stomach stagnation) were studied. The patients in the treatment group were randomly divided into treatment group (n = 36) and control group (n = 36). The control group was given 10g of Kuidekang granules produced by Dalian Pan am Pharmaceutical Co., Ltd (approval symbol: Z10970079) twice a day. The course of treatment in both groups was 28 days. The evaluation criteria of TCM symptoms and gastroscopy were used as the evaluation criteria. Results: one, 72 cases were actually included in this study, and 0 cases were dropped off and eliminated. The compliance of the two groups was good. The therapeutic effect was analyzed 28 days after treatment. The total score of symptoms after treatment in the two groups was statistically analyzed (P 0.01), which was statistically significant. After treatment, there was no statistical significance in the improvement of symptoms such as cold drinks, noise, constipation and other symptoms, such as cold drinks, noise, constipation, etc. In terms of emotional depression or irritability and irritability, the treatment group was better than the control group, and the treatment group was better than the control group. After statistical treatment, P 0.05, there was statistical significance. After treatment, the curative effect of gastroscope was compared between the two groups. There were no adverse events in both groups. Conclusion: YYYG treatment group can effectively treat peptic ulcer (liver and stomach stagnation and heat type), and the clinical effect is better than Kuidekang granule. Both drugs can effectively improve TCM syndromes, but Yiyang granule can improve the symptoms of epigastric pain, dry mouth, burning heat, acid swallow, emotional depression or irritability and irritability, and so on, which is worthy of further clinical study.
【學(xué)位授予單位】：長春中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

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