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朝醫(yī)方“萬(wàn)金文武湯”加減治療2型糖尿病的臨床研究

發(fā)布時(shí)間:2018-03-19 20:54

  本文選題:萬(wàn)金文武湯 切入點(diǎn):2型糖尿病 出處:《延邊大學(xué)》2016年碩士論文 論文類型:學(xué)位論文


【摘要】:目的:通過(guò)朝醫(yī)方《萬(wàn)金文武湯》加減對(duì)太陰人2型糖尿病(氣陰兩虛型)的臨床療效分析,評(píng)價(jià)朝醫(yī)藥在治療2型糖尿病的有效性和臨床價(jià)值,并為朝醫(yī)治療該病提供科學(xué)依據(jù)。方法:將2014年1月至2016年1月期間,延邊朝醫(yī)醫(yī)院和延邊中醫(yī)醫(yī)院門診及住院部收治的太陰人2型糖尿病患者60例,隨機(jī)分為治療組和對(duì)照組各30例,兩組均采用基礎(chǔ)治療,糖尿病知識(shí)教育、個(gè)體化的營(yíng)養(yǎng)治療和運(yùn)動(dòng)療法。對(duì)照組口服二甲雙胍,每次0.5g,每日3次;治療組在口服二甲雙胍基礎(chǔ)上加服萬(wàn)金文武湯(海松子12g、葛根20g、黃芩12g、藁本12g、天門冬6g、麥門冬6g、桔梗6g、白芷6g、大黃6g、升麻6g、萊菔子6g五味子6g)治療。4周為1個(gè)療程,治療3個(gè)療程后,觀察臨床癥狀變化并統(tǒng)計(jì)分析比較治療前后空腹血糖、餐后2小時(shí)血糖、糖化血紅蛋白、總膽固醇、甘油三酯、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇、中醫(yī)癥狀積分等指標(biāo)的變化情況,根據(jù)療效判定標(biāo)準(zhǔn),進(jìn)行療效評(píng)價(jià)。結(jié)果:總有效率:治療組優(yōu)于對(duì)照組(P0.05);臨床癥狀:治療組改善臨床癥狀的程度明顯優(yōu)于對(duì)照組(P0.05);血糖及糖化血紅蛋白:兩組均能降低FPG、2hPG、HbAlc,治療組明顯較對(duì)照組的療效更高(P0.05);血脂:治療組能夠明顯調(diào)節(jié)異常改變的血脂,其改善效果優(yōu)于對(duì)照組(P0.05)。結(jié)論:朝醫(yī)方《萬(wàn)金文武湯》加減聯(lián)合西藥治療太陰人2型糖尿病療效確切,在控制血糖,改善臨床癥狀等方面優(yōu)于單純西醫(yī)藥治療。
[Abstract]:Objective: to evaluate the effectiveness and clinical value of Korean medicine in the treatment of type 2 diabetes mellitus (deficiency of qi and yin) by adding and subtracting Wanjin Wenwu decoction. Methods: from January 2014 to January 2016, 60 patients with type 2 diabetes mellitus of Taiyin were treated in Yanbian Korean Medical Hospital and Yanbian traditional Chinese Medicine Hospital. They were randomly divided into treatment group (n = 30) and control group (n = 30). Both groups were treated with basic treatment, knowledge education of diabetes mellitus, individualized nutrition therapy and exercise therapy. The treatment group was treated with Wanjin Wenwu decoction (sea pine seed 12g, Pueraria lobata 20g, Scutellaria baicalensis 12g, ligustilium ligusticum 12g, Aspergillus asparagus 6g, Radix angelicae dahurica 6g, Rhubarb 6g, Radix Cassiae 6g, Raphani seed 6g Schisandra chinensis 6g) on the basis of oral metformin. After 3 courses of treatment, the changes of clinical symptoms were observed and compared with those before and after treatment, including fasting blood glucose, 2 hours postprandial blood glucose, glycosylated hemoglobin, total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol. The change of TCM symptom integral and other indexes, according to the criteria of curative effect, Results: the total effective rate: the treatment group was superior to the control group (P 0.05N); the clinical symptom: the treatment group improved the clinical symptoms obviously than the control group (P 0.05); the blood sugar and glycosylated hemoglobin: both groups could reduce the FPG2hPGN HbAlc, the treatment group was obviously better than the control group. The therapeutic effect was higher than that of the control group (P 0.05). Blood lipid: the treatment group was able to regulate the abnormal blood lipid obviously. Conclusion: the combination of Chinese medicine and western medicine is effective in the treatment of Taiyin type 2 diabetes mellitus. It is superior to western medicine in controlling blood sugar and improving clinical symptoms.
【學(xué)位授予單位】:延邊大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類號(hào)】:R29

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1 申君哲;朝醫(yī)方“萬(wàn)金文武湯”加減治療2型糖尿病的臨床研究[D];延邊大學(xué);2016年

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