本文選題：慢性阻塞性肺疾病急性加重期　切入點(diǎn)：貧血　出處：《成都中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：探討AECOPD合并貧血的血紅蛋白值分布及AECOPD合并貧血的患病率、貧血類型和貧血程度；探討年齡、BMI、病程、急性加重時(shí)間、住院時(shí)間等指標(biāo)與AECOPD合并貧血是否具有相關(guān)性；探討AECOPD合并貧血的中醫(yī)證型分布規(guī)律,從而為臨床中西醫(yī)結(jié)合防治AECOPD合并貧血提供一定的理論基礎(chǔ)。方法：①記錄血紅蛋白值,觀察血紅蛋白值分布情況,并根據(jù)血紅蛋白值進(jìn)行分組,統(tǒng)計(jì)各組的患病率,分析其貧血類型及貧血程度;②記錄性別、年齡、吸煙、居住地、BMI、病程、急性加重時(shí)間、住院時(shí)間等,運(yùn)用SPSS 17.0軟件進(jìn)行統(tǒng)計(jì)學(xué)分析,比較上述指標(biāo)在各組之間是否具有統(tǒng)計(jì)學(xué)差異；③記錄AECOPD合并貧血患者的中醫(yī)證型及舌質(zhì)、舌苔、脈象等,分析其分布規(guī)律。結(jié)果：①341例AECOPD中合并貧血者70例(20.53%),合并高血紅蛋白者18例(5.28%),血紅蛋白正常者253例(74.19%)；②貧血類型：正細(xì)胞性貧血48例(68.57%),小細(xì)胞性低色素性貧血19例(27.14%),巨幼細(xì)胞性貧血3例(4.29%)；③貧血程度：輕度貧血58例(82.86%),中度貧血12例(17.14%),重度、極重度貧血均0例；④運(yùn)用SPSS 17.0統(tǒng)計(jì)分析：貧血組平均年齡較高血紅蛋白血癥組高,貧血組BMI較高血紅蛋白血癥組低；貧血組平均住院時(shí)間較高血紅蛋白血癥組長(zhǎng),貧血組急性加重時(shí)間較高血紅蛋白血癥組短；住院時(shí)間、急性加重時(shí)間、年齡、BMI在貧血組與高血紅蛋白血癥組間比較,差異具有統(tǒng)計(jì)學(xué)意義(P0.05),而病程在貧血組與高血紅蛋白血癥組間比較,差異不具有統(tǒng)計(jì)學(xué)意義(P0.05)；住院時(shí)間、急性加重時(shí)間、病程、年齡、BMI在各貧血組間比較,差異均不具有統(tǒng)計(jì)學(xué)意義(P0.05);⑤70例AECOPD合并貧血證型中實(shí)證50例(71.43%),虛證12例(17.14%),虛實(shí)夾雜8例(11.43%),實(shí)證中濕證者28例(56.00%)。結(jié)論:①ECOPD合并貧血的患病率為20.53%,AECOPD合并高血紅蛋白血癥的患病率為5.28%；②貧血程度以輕度貧血為主,貧血類型以正細(xì)胞性貧血為主；③隨著血紅蛋白水平的下降,疾病急性加重時(shí)間縮短、住院時(shí)間延長(zhǎng);④AECOPD合并貧血的發(fā)生與年齡、營(yíng)養(yǎng)狀況有關(guān)；⑤AECOPD合并貧血的證型分布以實(shí)證為主,虛證次之,實(shí)證中以濕證多見(jiàn)。
[Abstract]:Objective: to investigate the distribution of hemoglobin value in AECOPD complicated with anemia, the prevalence, type and degree of anemia in AECOPD, and the correlation between age, course of disease, time of acute exacerbation, length of hospitalization and AECOPD with anemia. In order to provide a theoretical basis for the prevention and treatment of AECOPD with anemia by combining traditional Chinese medicine and western medicine, the distribution of TCM syndromes in AECOPD complicated with anemia was discussed. Methods the hemoglobin value was recorded at 1: 1 and the distribution of hemoglobin value was observed. The patients were divided into groups according to hemoglobin value, the prevalence rate of each group was counted, the type of anemia and the degree of anemia were analyzed, the sex, age, smoking, BMIs, course of disease, time of acute exacerbation, time of hospitalization, etc. SPSS 17.0 software was used to make statistical analysis, and to compare whether the above indexes had statistical difference among the groups. The TCM syndromes, tongue coating, pulse and so on were recorded in patients with AECOPD complicated with anemia. Results among 1341 cases of AECOPD, 70 cases had anemia, 18 cases had high hemoglobin, 253 cases had normal hemoglobin and 74.19 cases had anemic type: 48 cases of normal cell anemia (48 cases), 68.57% of anemia, 19 cases of small cell hypochromic anemia (27.14). 3 cases of megaloblastic anemia (4. 29%): 58 cases with mild anemia (82.86%), 12 cases with moderate anemia (17. 14%) with severe anemia, SPSS 17.0 statistical analysis showed that the average age of anemia group was higher than that of high hemoglobinemia group, the BMI of anemia group was lower than that of hyperhemoglobinemia group, the average hospitalization time of anemia group was higher than that of hyperhemoglobinemia group, and that of anemia group was higher than that of high hemoglobinemia group. The acute exacerbation time of anemia group was shorter than that of hyperhemoglobinemia group; the time of hospitalization, acute exacerbation time, age and BMI were compared between anemia group and hyperhemoglobinemia group. The difference was statistically significant (P 0.05), but there was no significant difference in the course of disease between anemia group and hyperhemoglobinemia group (P 0.05), the duration of hospitalization, acute exacerbation time, course of disease, age and BMI were compared among the anemia groups, and there was no significant difference in the course of disease between the anemia group and the hyperhemoglobinemia group. The difference was not statistically significant in 50 cases of AECOPD with anemia syndrome, 12 cases of deficiency syndrome and 17.14% of deficiency syndrome, 8 cases of deficiency syndrome and 8 cases of deficiency syndrome, and 28 cases of dampness syndrome with anemia in 28 cases. Conclusion the prevalence rate of W1 ECOPD with anemia is 20.53 AECOPD with hyperhemoglobin. The prevalence of anemia was 5.28% and mild anemia was the main anemia. With the decrease of hemoglobin level, the acute exacerbation time of the disease was shortened, and the occurrence of 4AECOPD complicated with anemia was prolonged with age, and the distribution of the syndrome type of 5AECOPD with anemia related to nutritional status was mainly positive. Deficiency syndrome followed by dampness syndrome.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

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