本文選題：益腎活血方　切入點(diǎn)：人絨毛膜促性腺激素(HCG)注射液　出處：《河南中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:通過(guò)觀察及研究治療組、對(duì)照組的腎虛血瘀型LUFS的排卵率,探討中藥口服加灌腸聯(lián)合HCG注射液治療未破裂卵泡黃素化綜合征(luteinized unruptured follicle syndrome,LUFS)的優(yōu)勢(shì),為臨床應(yīng)用及推廣提供客觀依據(jù)。方法:隨機(jī)收集2014年10月至2015年10月于河南中醫(yī)學(xué)院第一附屬醫(yī)院婦科門診就診的符合診斷與納入標(biāo)準(zhǔn)的LUFS患者60例,完全隨機(jī)分為兩組,以益腎活血方口服+活血灌腸方灌腸+HCG注射液為治療組,共30例;以注射用絨促性素(human chorionic gonadotropin,HCG)注射液為對(duì)照組,共30例。療程為3個(gè)月經(jīng)周期。觀察兩組治療后排卵率;比較兩組治療前后注射HCG注射液(注射前)當(dāng)天血LH水平;比較兩組治療前后中醫(yī)證候積分。結(jié)果:(1)入組患者在年齡、病程、不孕類型、治療前中醫(yī)證候積分及血LH水平經(jīng)統(tǒng)計(jì)學(xué)分析,均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),說(shuō)明兩組基線資料具有可比性。治療組治療前后的中醫(yī)證候經(jīng)統(tǒng)計(jì)學(xué)分析,有統(tǒng)計(jì)學(xué)意義(P0.05),對(duì)照組治療前后的中醫(yī)證候經(jīng)統(tǒng)計(jì)學(xué)分析,無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);(3)治療組排卵率71.9%,對(duì)照組排卵率52.9%,兩組排卵率經(jīng)統(tǒng)計(jì)學(xué)分析,有統(tǒng)計(jì)學(xué)意義(P0.05);(4)治療組治療前后血LH水平經(jīng)統(tǒng)計(jì)學(xué)分析,有統(tǒng)計(jì)學(xué)意義(P0.05);對(duì)照組治療前后血LH水平經(jīng)統(tǒng)計(jì)學(xué)分析,無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);兩組治療后血LH水平經(jīng)統(tǒng)計(jì)學(xué)分析,有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:(1)中藥口服加灌腸聯(lián)合HCG注射液對(duì)腎虛血瘀型LUFS患者的中醫(yī)臨床證候有改善作用;(2)中藥口服加灌腸聯(lián)合HCG注射液對(duì)腎虛血瘀型LUFS患者的排卵率有提高作用;(3)中藥口服加灌腸聯(lián)合HCG注射液能提高腎虛血瘀型LUFS患者HCG注射當(dāng)天(注射前)的LH水平;(4)治療組對(duì)改善中醫(yī)臨床證候、提高排卵率及提高血LH水平的效果均優(yōu)于對(duì)照組。
[Abstract]:Objective: to observe and study the ovulation rate of LUFS of kidney deficiency and blood stasis type in the treatment group and control group, and to explore the advantages of traditional Chinese medicine plus enema combined with HCG injection in the treatment of unruptured unruptured follicle syndromes. Methods: from October 2014 to October 2015, 60 LUFS patients who met the criteria of diagnosis and inclusion in gynecological clinic of the first affiliated Hospital of Henan College of traditional Chinese Medicine were randomly divided into two groups. 30 cases were treated with Yishen Huoxue decoction, 30 cases were treated with Huoxue enema recipe enema HCG injection, 30 cases were treated with chorionic chorionic gonadotropin (HCG) injection for injection, the course of treatment was 3 menstrual cycles. The ovulation rate was observed after treatment in both groups. Serum LH levels before and after injection of HCG injection (before injection) were compared between the two groups, and TCM syndromes scores before and after treatment were compared. Results: age, course of disease, type of infertility, Before treatment, the scores of TCM syndromes and serum LH levels were not statistically significant (P 0.05), which indicated that the baseline data of the two groups were comparable, and the TCM syndromes before and after treatment in the treatment group were statistically analyzed. There was significant difference in the ovulation rate of the treatment group (71.9%) and the control group (52.9%). The ovulation rate of the two groups was statistically analyzed. Serum LH levels before and after treatment in the treatment group were statistically significant, while in the control group, there was no statistical significance in the blood LH level before and after treatment; after treatment, the serum LH level in the two groups was statistically analyzed. Conclusion the Chinese medicine oral enema combined with HCG injection can improve the clinical syndromes of LUFS patients with kidney deficiency and blood stasis syndrome. Conclusion the ovulation of LUFS patients with kidney deficiency and blood stasis type treated by Chinese medicine oral administration plus enema combined with HCG injection can be improved by traditional Chinese medicine oral administration and enema combined with HCG injection. The oral administration of traditional Chinese medicine plus enema combined with HCG injection can improve the LH level of LUFS patients with kidney deficiency and blood stasis on the same day (before injection) the treatment group can improve the clinical syndromes of traditional Chinese medicine. The effect of increasing ovulation rate and serum LH level was better than that of control group.
【學(xué)位授予單位】：河南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R271.9

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