本文選題：毒性彌漫性甲狀腺腫　切入點(diǎn)：心理穩(wěn)定性　出處：《中華中醫(yī)藥雜志》2017年02期 　論文類(lèi)型：期刊論文

【摘要】：目的:探討新發(fā)毒性彌漫性甲狀腺腫(Graves)病患者日間功能、睡眠質(zhì)量、心理穩(wěn)定性的變化。方法:采用現(xiàn)況調(diào)研及病例對(duì)照研究方法,調(diào)查新發(fā)Graves病患者581例及健康對(duì)照800名。被調(diào)查者填寫(xiě)一般資料量表、憤怒郁怒體質(zhì)調(diào)查表、匹茲堡睡眠質(zhì)量指數(shù)量表(PSQI)、疲勞評(píng)定量表(FAI)�；厥諉�(wèn)卷,進(jìn)行病例對(duì)照的多因素非條件Logistic回歸分析。結(jié)果:多數(shù)新發(fā)Graves病患者日間功能差、睡眠質(zhì)量下降、心理穩(wěn)定性下降等發(fā)生的風(fēng)險(xiǎn)較大。心理穩(wěn)定性下降發(fā)生風(fēng)險(xiǎn)存在性別差異,女性患者發(fā)生風(fēng)險(xiǎn)較大。睡眠質(zhì)量下降表現(xiàn)在多維度,不同年齡、性別表現(xiàn)的維度不同。年齡大者表現(xiàn)為入睡所需時(shí)間延長(zhǎng),其發(fā)生風(fēng)險(xiǎn)度最大為健康對(duì)照組的1.235倍。不足30歲者僅在疲勞時(shí)心理穩(wěn)定性下降。結(jié)論:Graves病為心身疾病,臨床診治時(shí)除典型癥狀外應(yīng)注意患者有無(wú)日間功能障礙、睡眠質(zhì)量下降、心理穩(wěn)定性變差等,不同性別、年齡階段問(wèn)診側(cè)重點(diǎn)不同,針對(duì)不同癥狀給予相應(yīng)的藥物或心理治療,以提高抗甲狀腺藥物治療效果。
[Abstract]:Objective: to investigate the changes of daytime function, sleep quality and psychological stability in patients with new toxic diffuse goiter Graves disease. 581 newly diagnosed patients with Graves disease and 800 healthy controls were investigated. The respondents filled out general information scale, anger depression constitution questionnaire, Pittsburgh Sleep quality Index scale and fatigue rating scale. Multivariate conditional Logistic regression analysis was performed on the patients with Graves disease. Results: most of the newly diagnosed Graves patients had a higher risk of poor daytime function, lower sleep quality and lower psychological stability. Female patients are at greater risk. Sleep quality decline is manifested in multiple dimensions, different ages, different dimensions of gender performance. Older women show longer time to fall asleep. The maximum risk of the disease was 1.235 times of that of the healthy control group. The psychological stability of the patients under 30 years of age decreased only when they were tired. Conclusion: Graves disease is a psychosomatic disease. In clinical diagnosis and treatment, attention should be paid to whether the patients have daytime dysfunction except for typical symptoms. In order to improve the therapeutic effect of antithyroid drugs, the quality of sleep was decreased, the psychological stability became worse, and the emphasis of consultation was different in different gender and age stage, and the corresponding drugs or psychotherapy were given to different symptoms in order to improve the therapeutic effect of antithyroid drugs.
【作者單位】： 濟(jì)南市中心醫(yī)院內(nèi)分泌科;聊城市人民醫(yī)院;山東中醫(yī)藥大學(xué)基礎(chǔ)醫(yī)學(xué)院;
【基金】：國(guó)家重點(diǎn)基礎(chǔ)研究發(fā)展計(jì)劃(973計(jì)劃)項(xiàng)目(No.2006CB504800)~~
【分類(lèi)號(hào)】：R259

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